Announcements Trials
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Phase

Phase EARLY_PHASE1 2Phase 2 1

Status

Completed 3Withdrawn 1

Sponsor Class

OTHER 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 140Leukemia 132Lymphoma 90Leukemia, Myeloid, Acute 62Myelodysplastic Syndromes 47Burkitt Lymphoma 46Lymphoma, Non-Hodgkin 44Lymphoma, Large B-Cell, Diffuse 37Breast Neoplasms 37Lymphoma, Mantle-Cell 33Leukemia, Lymphocytic, Chronic, B-Cell 33Hodgkin Disease 32Multiple Myeloma 29Congenital Abnormalities 29Myeloproliferative Disorders 27Lymphoma, Follicular 27Leukemia, Myeloid, Accelerated Phase 27Graft vs Host Disease 27Leukemia, Myelomonocytic, Chronic 25Lymphoma, Large-Cell, Immunoblastic 24Leukemia, Myeloid, Chronic-Phase 24Blast Crisis 24Lymphoma, B-Cell, Marginal Zone 22Leukemia, Myelogenous, Chronic, BCR-ABL Positive 20Anemia, Refractory, with Excess of Blasts 20Recurrence 18Primary Myelofibrosis 17Neoplasms, Plasma Cell 17Dendritic Cell Sarcoma, Interdigitating 17Osteosarcoma 16

Interventions

Temozolomide 13Filgrastim 8Carboplatin 8Radiotherapy 7Magnetic Resonance Spectroscopy 7Etoposide 7Cisplatin 7Cyclophosphamide 6Bevacizumab 6Vincristine 4Thiotepa 4Carmustine 4sargramostim 3Surveys and Questionnaires 3Peripheral Blood Stem Cell Transplantation 3Methotrexate 3Lapatinib 3Irinotecan 3Azacitidine 3veliparib 2alovudine 2aldesleukin 2Tamoxifen 2Radiotherapy, Conformal 2Radiation 2Paclitaxel 2Mental Status and Dementia Tests 2Imatinib Mesylate 2Granulocyte-Macrophage Colony-Stimulating Factor 2Granulocyte Colony-Stimulating Factor 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Completed × Ependymoma × Methotrexate × Clear all
NCT02905110 2025-03-25

Methotrexate and Etoposide Infusions Into the Fourth Ventricle in Children with Recurrent Posterior Fossa Brain Tumors

The University of Texas Health Science Center, Houston

Phase EARLY_PHASE1 Completed
3 enrolled
CNS

Brain Neoplasms, Ependymoma, Medulloblastoma, Rhabdoid Tumor

NCT01737671 2018-01-19

Methotrexate Infusion Into the Fourth Ventricle in Children With Malignant Fourth Ventricular Brain Tumors: A Pilot Study

M.D. Anderson Cancer Center

Phase EARLY_PHASE1 Completed
7 enrolled
CNS

Brain Neoplasms, Ependymoma, Medulloblastoma, Rhabdoid Tumor

NCT00006258 2013-07-18

Combination Chemotherapy Followed by Radiation Therapy in Treating Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma

National Cancer Institute (NCI)

Phase 2 Completed
CNS

Ependymoma, Medulloblastoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive

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