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Phase

Phase 1 1

Status

Completed 3Withdrawn 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 9Leukemia, Myeloid, Acute 8Leukemia 8Lymphoma 7Myelodysplastic Syndromes 5Leukemia, Myeloid, Chronic-Phase 5Graft vs Host Disease 5Central Nervous System Neoplasms 5Leukemia, Myeloid, Accelerated Phase 4Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Lymphoma, Non-Hodgkin 3Lymphoma, Large B-Cell, Diffuse 3Leukemia, Myelogenous, Chronic, BCR-ABL Positive 3Leukemia, Lymphocytic, Chronic, B-Cell 3Leukemia, Biphenotypic, Acute 3Burkitt Lymphoma 3Breast Neoplasms 3Waldenstrom Macroglobulinemia 2Sezary Syndrome 2Primary Myelofibrosis 2Myeloproliferative Disorders 2Mycosis Fungoides 2Lymphoma, T-Cell, Cutaneous 2Lymphoma, Mantle-Cell 2Lymphoma, Large-Cell, Immunoblastic 2Lymphoma, Large-Cell, Anaplastic 2Lymphoma, Follicular 2Lymphoma, Extranodal NK-T-Cell 2Lymphoma, B-Cell, Marginal Zone 2Leukemia, Myelomonocytic, Chronic 2

Interventions

Magnetic Resonance Spectroscopy 3Temozolomide 2thymoglobulin 1gallium Ga 68 dotatate 1fludarabine phosphate 1Thiotepa 1Tacrolimus 1Stem Cell Transplantation 1Radiotherapy 1Nivolumab 1Mycophenolic Acid 1Methotrexate 1Melphalan 1Hematopoietic Stem Cell Transplantation 1Gadolinium DTPA 1Etoposide 1Erlotinib Hydrochloride 1Biopsy 1Bandages 1Azacitidine 1Antilymphocyte Serum 12-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Withdrawn × Ependymoma × Methotrexate × Clear all
NCT06466798 2026-01-08

Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS Malignancies

The University of Texas Health Science Center, Houston

Phase 1 Withdrawn
CNS

Ependymoma, Medulloblastoma, Central Nervous System Neoplasms

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