Announcements Trials
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Phase

Phase 1/2 1Phase 1 1

Status

Completed 2

Sponsor Class

NIH 1NETWORK 1

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Sarcoma 1

Conditions

Breast Neoplasms 17Ovarian Neoplasms 15Triple Negative Breast Neoplasms 10Neoplasms 8Fallopian Tube Neoplasms 8Neoplasm Metastasis 7Carcinoma, Non-Small-Cell Lung 5Pancreatic Neoplasms 4Brain Neoplasms 4Astrocytoma 4Stomach Neoplasms 3Recurrence 3Prostatic Neoplasms 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Lymphoma 3Gliosarcoma 3Glioblastoma 3Colonic Neoplasms 3Breast Neoplasms, Male 3Uterine Cervical Neoplasms 2Small Cell Lung Carcinoma 2Rectal Neoplasms 2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Oligodendroglioma 2Melanoma 2Medulloblastoma 2Lymphoma, T-Cell 2Lymphoma, Mantle-Cell 2Lymphoma, Follicular 2Lung Neoplasms 2

Interventions

Temozolomide 13Filgrastim 8Carboplatin 8Radiotherapy 7Magnetic Resonance Spectroscopy 7Etoposide 7Cisplatin 7Cyclophosphamide 6Bevacizumab 6Vincristine 4Thiotepa 4Carmustine 4sargramostim 3Surveys and Questionnaires 3Peripheral Blood Stem Cell Transplantation 3Methotrexate 3Lapatinib 3Irinotecan 3Azacitidine 3veliparib 2alovudine 2aldesleukin 2Tamoxifen 2Radiotherapy, Conformal 2Radiation 2Paclitaxel 2Mental Status and Dementia Tests 2Imatinib Mesylate 2Granulocyte-Macrophage Colony-Stimulating Factor 2Granulocyte Colony-Stimulating Factor 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Completed × Ependymoma × veliparib × Clear all
NCT00994071 2019-12-09

A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
9 enrolled
CNS

Astrocytoma, Brain Neoplasms, Ependymoma, Medulloblastoma, Neuroectodermal Tumors, Primitive

NCT01026493 2017-07-02

Veliparib and Temozolomide in Treating Patients With Recurrent Glioblastoma

Radiation Therapy Oncology Group

Phase 1/2 Completed
257 enrolled 16 charts
CNSSarcoma

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

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