Clinical Trials

Phase 1/2 Not yet recruiting

Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Recurrence

NCT06639607 2026-03-10

PRiME II

68 enrolled

Diffuse Intrinsic Pontine Glioma, Ependymoma, Medulloblastoma, Recurrence

NCT04238819 2026-03-02

A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

47 enrolled 36 charts

Phase 1/2 Active not recruiting

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Rhabdoid Tumor

NCT06521567 2025-11-12

A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

83 enrolled

CNSDermatologicGastrointestinalLymphoidSarcoma

Fibrolamellar hepatocellular carcinoma, Diffuse Intrinsic Pontine Glioma, Ependymoma, Glioblastoma, Carcinoma, Hepatocellular, Hodgkin Disease, Melanoma, Rhabdomyosarcoma, Osteosarcoma, Hepatoblastoma

NCT06485908 2024-07-03

MEPENDAX

Phase 1/2 Not yet recruiting

40 enrolled

Ependymoma, Medulloblastoma

NCT01721577 2023-05-22

AXL1717

Phase 1/2 Terminated

10 enrolled 8 charts

CNSDermatologicLymphoidOther hematologic neoplasmSarcoma

Astrocytoma, Ependymoma, Glioblastoma, Oligodendroglioma, Gliosarcoma

NCT04730349 2023-03-24

PIVOT IO 020

Phase 1/2 Terminated

15 enrolled 14 charts

Ependymoma, Glioma, Leukemia, Lymphoma, Lymphoma, Non-Hodgkin, Medulloblastoma, Melanoma, Neoplasms, Neuroblastoma, Recurrence, Rhabdomyosarcoma, Sarcoma, Ewing, Leukemia, B-Cell

NCT01024907 2020-12-10

Proton Beam Radiation Therapy in Treating Patients With Low Grade Gliomas

23 enrolled

Astrocytoma, Brain Neoplasms, Ependymoma, Glioma, Oligodendroglioma, Pinealoma

NCT01026493 2017-07-02

Veliparib and Temozolomide in Treating Patients With Recurrent Glioblastoma

257 enrolled 16 charts

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00002752 2014-07-16

Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Cancers

Familial ependymoma, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neoplasm Metastasis, Oligodendroglioma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

NCT00009854 2013-11-06

Carmustine Followed By Surgery in Treating Patients With Recurrent Supratentorial Malignant Glioma or Metastatic Brain Neoplasm

Phase 1/2 Unknown

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Neoplasm Metastasis, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003478 2013-02-20

Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary Brain Tumors

10 enrolled