Clinical Trials

Epilepsy, Neuroblastoma

NCT07460037 2026-03-10

Chinese-Specific Speech Imagery Coding Using High-Density ECoG

Phase NA Recruiting

50 enrolled

Locked-In Syndrome, Aphasia, Dysarthria, Epilepsy, Language Disorders, Speech, Stroke

NCT05104983 2026-01-22

TSC-STEPS

Phase 2 Recruiting

64 enrolled

Epilepsy, Tuberous Sclerosis

NCT04266041 2025-12-12

High-density EEG in Neurological Disorders

122 enrolled 18 charts

Epilepsy, Language, Neoplasms, Stroke

NCT05626634 2025-12-03

Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy

41 enrolled

CDKL5 deficiency disorder, Epilepsy, Epilepsies, Myoclonic, Tuberous Sclerosis, Lennox Gastaut Syndrome

NCT04485104 2025-10-31

Assessment of Adjunctive Cannabidiol Oral Solution (GWP42003-P) in Children With Tuberous Sclerosis Complex (TSC), Dravet Syndrome (DS), or Lennox-Gastaut Syndrome (LGS) Who Experience Inadequately-controlled Seizures

Phase 3 Terminated

3 enrolled 28 charts

Tuberous Sclerosis 1, Tuberous Sclerosis 2, Epilepsy, Epilepsies, Myoclonic, Seizures, Spasms, Infantile, Tuberous Sclerosis, Lennox Gastaut Syndrome

NCT05014841 2025-09-16

The Neural Coding of Speech Across Human Languages

52 enrolled

Phase 3 Active not recruiting

Brain Neoplasms, Epilepsy, Speech

NCT07165262 2025-09-10

ECOG-Anaes

88 enrolled

Brain Neoplasms, Epilepsy

NCT06391294 2025-09-09

Neuronal and Network Mechanisms of Electrocortical Stimulation

65 enrolled

Epilepsy

NCT05989893 2025-08-28

Mapping of Human Cognition

Phase NA Recruiting

75 enrolled

Phase 4 Enrolling by invitation

Brain Neoplasms, Epilepsy, Seizures

NCT02670161 2025-08-24

Quality Improvement and Practice Based Research in Neurology Using the EMR

3,300 enrolled

Brain Concussion, Brain Neoplasms, Epilepsy, Migraine Disorders, Multiple Sclerosis, Parkinson Disease, Restless Legs Syndrome, Stroke, Cognitive Dysfunction

NCT03731455 2025-07-17

WIN

32 enrolled

Epilepsy

NCT05435859 2025-06-08

Functional Organization of the Superior Temporal Gyrus for Speech Perception

60 enrolled

Phase NA Not yet recruiting

Brain Neoplasms, Epilepsy, Speech

NCT06408428 2025-03-12

MicroECoGG

50 enrolled

Phase EARLY_PHASE1 Active not recruiting

Epilepsy, Glioma

NCT05364021 2024-11-08

PACIFIC

Phase 1/2 Completed

52 enrolled

CDKL5 deficiency disorder, Epilepsy, Epilepsies, Myoclonic, Tuberous Sclerosis, Lennox Gastaut Syndrome

NCT02134067 2024-09-05

Dose-escalating, Safety, Tolerability and PK Study of TAS-119 in Combination With Paclitaxel in Patients With Advanced Solid Tumors

Phase 1 Terminated

30 enrolled

Epilepsy, Neoplasms

NCT05029960 2024-08-09

Tolerability and Activity of Brivaracetam (BRV) in Patients With Diffuse Gliomas

30 enrolled

Brain Neoplasms, Epilepsy

NCT04595513 2024-05-16

STOP2

Phase 1/2 Completed

5 enrolled 15 charts

Epilepsy, Tuberous Sclerosis

NCT06412692 2024-05-14

Motivational Interviewing in Adolescents With Epilepsy

LymphoidOther hematologic neoplasm

72 enrolled

Epilepsy, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05664464 2024-05-10

GLUGLIO

Phase 1/2 Recruiting

120 enrolled

Epilepsy, Glioblastoma

NCT04152109 2024-05-08

PICS

Phase NA Recruiting

60 enrolled

Epilepsy, Neoplasms

NCT04987463 2024-02-08

ViRap

Phase 2/3 Unknown

60 enrolled

Epilepsy, Neoplasms, Tuberous Sclerosis

NCT05068869 2023-12-01

Digital Outpatient Services

180 enrolled

Epilepsy, Neoplasms, Personal Satisfaction, Lung Diseases, Interstitial

NCT04344626 2023-10-10

Use of a Tonometer to Identify Epileptogenic Lesions During Pediatric Epilepsy Surgery

Phase NA Withdrawn

Focal Cortical Dysplasia, Brain Neoplasms, Encephalitis, Epilepsy, Gliosis, Sturge-Weber Syndrome, Tuberous Sclerosis, Stroke, Hemimegalencephaly, Polymicrogyria

NCT05534672 2023-08-08

RaRE-TS

Phase 3 Recruiting

200 enrolled

Drug Resistant Epilepsy, Epilepsy, Tuberous Sclerosis

NCT04650204 2023-06-22

Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy

Phase 4 Terminated

4 enrolled 9 charts

Drug Resistant Epilepsy, Epilepsy, Glioma

NCT03944447 2022-06-02

OMNI-Can

Phase 2 Unknown

200,000 enrolled

Classical hematology

Chronic Traumatic Encephalopathy, Brain Injuries, Traumatic, COVID-19, Acquired Immunodeficiency Syndrome, Amyotrophic Lateral Sclerosis, Anemia, Sickle Cell, Anxiety Disorders, Autistic Disorder, Bipolar Disorder, Colitis, Ulcerative, Crohn Disease, Depression, Epilepsy, Fibromyalgia, Tourette Syndrome, Glaucoma, Hepatitis C, Sleep Initiation and Maintenance Disorders, Multiple Sclerosis, Opioid-Related Disorders, Neoplasms, Parkinson Disease, Seizures, Stress Disorders, Post-Traumatic, Inflammatory Bowel Diseases, Coronavirus Infections, Severe Acute Respiratory Syndrome, Chronic Pain

NCT04737174 2022-04-06

ES-481 for Uncontrolled Glioma-Associated Epilepsy and Assessment for Potential Anti-Tumorigenic Effect in Patients With Isocitrate Dehydrogenase 1 (IDH1) Mutant Tumors

Phase 2 Withdrawn

Epilepsy

NCT02451696 2021-09-01

A Pilot Study To Evaluate The Effects of Everolimus on Brain mTOR Activity and Cortical Hyperexcitability in TSC and FCD

15 enrolled 9 charts

Focal Cortical Dysplasia, Epilepsy, Tuberous Sclerosis

NCT03898791 2021-08-05

A Study of LY3295668 Erbumine in Participants With Extensive-stage Small-Cell Lung Cancer

Phase 1 Completed

48 enrolled

Thoracic

Epilepsy, Small Cell Lung Carcinoma

NCT03650452 2021-02-18

ELEKTRA

141 enrolled 24 charts

CDKL5 deficiency disorder, Brain Diseases, Central Nervous System Diseases, Epilepsy, Epilepsies, Myoclonic, Nervous System Diseases, Seizures, Spasms, Infantile, Tuberous Sclerosis, Hypoxia-Ischemia, Brain, Malformations of Cortical Development, Lennox Gastaut Syndrome

NCT03422367 2020-11-06

JETS

64 enrolled

Autistic Disorder, Child Development Disorders, Pervasive, Epilepsy, Tuberous Sclerosis

NCT03356769 2020-06-09

Aspirin as an add-on Treatment of Refractory Epilepsy in Tuberous Sclerosis Complex

Phase 2 Unknown

98 enrolled

Epilepsy, Seizures, Tuberous Sclerosis, Cognitive Dysfunction

NCT03955939 2020-06-01

A Study of LY3295668 Erbumine in Participants With Breast Cancer That Has Spread to Other Parts of the Body

Phase 1 Completed

5 enrolled

Breast

Breast Neoplasms, Epilepsy

NCT03513757 2020-02-21

Dexmedetomidine and Propofol for Pediatric MRI Sedation

Phase 4 Completed

40 enrolled 15 charts

Abdominal Neoplasms, Epilepsy, Headache, Hydrocephalus, Neoplasms, Neurofibromatoses

NCT00179517 2019-07-17

Treatment of Sexual Dysfunction in Hypogonadal Men With Epilepsy With Testosterone and Either Anastrozole or Placebo

40 enrolled 13 charts

EndocrineOther

Epilepsy, Hypogonadism, Erectile Dysfunction, Seizures, Sexual Dysfunction, Physiological, Multiple Endocrine Neoplasia Type 1

NCT03254680 2018-04-30

Turmeric as Treatment in Epilepsy

Phase NA Withdrawn

Epilepsy, Epilepsies, Myoclonic, Seizures, Tuberous Sclerosis, Lennox Gastaut Syndrome

NCT01070316 2017-03-13

Everolimus (RAD001) Therapy for Epilepsy in Patients With Tuberous Sclerosis Complex (TSC)

Phase 1/2 Completed

20 enrolled 8 charts

Epilepsy, Hereditary Sensory and Autonomic Neuropathies, Tuberous Sclerosis

NCT02885207 2016-08-31

IBADEPIF

200 enrolled

Epilepsy, Limbic Encephalitis

NCT01997255 2016-05-05

Adjunctive Everolimus (RAD 001) Therapy for Epilepsy in Children With Sturge-Weber Syndrome (SWS)

Phase 2 Withdrawn

Epilepsy, Glaucoma, Sturge-Weber Syndrome, Port-Wine Stain

NCT02015806 2016-01-11

REMIND

53,480 enrolled

BreastGenitourinary

Mental Disorders, Breast Neoplasms, Cardiovascular Diseases, Depression, Diabetes Mellitus, Epilepsy, Parkinson Disease, Prostatic Hyperplasia, Medication Adherence

NCT00952081 2015-02-09

A Pilot Study to Evaluate Efficacy and Safety of Clevidipine in Neurosurgical Patients

Phase 4 Completed

22 enrolled 5 charts

Brain Neoplasms, Epilepsy, Hypertension

NCT01545518 2014-09-01

IVIG Treatment for Refractory Immune-Related Adult Epilepsy

Phase 2 Terminated

20 enrolled 3 charts

Drug Resistant Epilepsy, Autoimmune Diseases, Epilepsy, Epilepsies, Partial, Autoimmune Diseases of the Nervous System, Limbic Encephalitis

NCT02098759 2014-04-04

EPISTOP

100 enrolled

Epilepsy, Tuberous Sclerosis

NCT00972790 2012-03-01

Scalp Nerve Blocks for Post-Craniotomy Pain

89 enrolled

Aneurysm, Arteriovenous Malformations, Brain Neoplasms, Epilepsy, Supratentorial Neoplasms

NCT00639730 2010-05-27

Use of the Atkins Diet for Children With Sturge Weber Syndrome

Phase 1 Completed

5 enrolled

Epilepsy, Sturge-Weber Syndrome

NCT00571155 2009-08-20

Trial of Levetiracetam in Patients With Primary Brain Tumors and Symptomatic Seizures Who Undergo Surgery

Phase 4 Completed

30 enrolled