Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Terminated 1Active not recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Head & Neck 2

Conditions

Breast Neoplasms 84Neoplasm Metastasis 59Prostatic Neoplasms 57Leukemia, Myeloid, Acute 57Melanoma 49Multiple Myeloma 47Colorectal Neoplasms 44Lung Neoplasms 43Pancreatic Neoplasms 39Carcinoma, Non-Small-Cell Lung 38Lymphoma 37Neoplasms 30Myelodysplastic Syndromes 30Leukemia, Lymphocytic, Chronic, B-Cell 30Squamous Cell Carcinoma of Head and Neck 28Lymphoma, Large B-Cell, Diffuse 25Triple Negative Breast Neoplasms 24Ovarian Neoplasms 24Burkitt Lymphoma 21Rectal Neoplasms 20Lymphoma, Follicular 19Colonic Neoplasms 19Uterine Cervical Neoplasms 18Stomach Neoplasms 18Sarcoma 18Precursor Cell Lymphoblastic Leukemia-Lymphoma 18Carcinoma, Renal Cell 18Lymphoma, Mantle-Cell 17Glioma 17Head and Neck Neoplasms 16

Interventions

Metformin 3Biopsy 2Surveys and Questionnaires 1Spectrometry, Fluorescence 1Specimen Handling 1Optical Imaging 1Molecular Diagnostic Techniques 1Aminolevulinic Acid 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Erythroplasia × Biopsy × Clear all
NCT05237960 2026-04-20

Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia

University of Arizona

Phase 2 Active not recruiting
34 enrolled
Head & Neck

Erythroplasia, Leukoplakia, Oral

NCT05536037 2025-05-15

Metformin for the Prevention of Oral Cancer in Patients With Oral Premalignant Lesions

Thomas Jefferson University

Phase 1 Terminated
4 enrolled
Head & Neck

Erythroplasia, Leukoplakia, Mouth Neoplasms

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