Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Terminated 1Active not recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Head & Neck 2

Conditions

Breast Neoplasms 68Prostatic Neoplasms 44Leukemia, Myeloid, Acute 35Melanoma 34Lung Neoplasms 28Carcinoma, Non-Small-Cell Lung 28Pancreatic Neoplasms 26Myelodysplastic Syndromes 23Multiple Myeloma 23Colorectal Neoplasms 23Leukemia, Lymphocytic, Chronic, B-Cell 22Neoplasms 21Squamous Cell Carcinoma of Head and Neck 19Neoplasm Metastasis 19Lymphoma, Large B-Cell, Diffuse 19Rectal Neoplasms 16Lymphoma, Mantle-Cell 14Carcinoma, Renal Cell 14Triple Negative Breast Neoplasms 13Stomach Neoplasms 13Precursor Cell Lymphoblastic Leukemia-Lymphoma 13Colonic Neoplasms 13Lymphoma, Follicular 12Uterine Cervical Neoplasms 11Ovarian Neoplasms 11Leukemia, Myelomonocytic, Chronic 11Head and Neck Neoplasms 11Esophageal Neoplasms 11Myeloproliferative Disorders 10Mouth Neoplasms 9

Interventions

Metformin 2Biopsy 2Surveys and Questionnaires 1Spectrometry, Fluorescence 1Specimen Handling 1Optical Imaging 1Molecular Diagnostic Techniques 1Aminolevulinic Acid 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
OTHER × Erythroplasia × Biopsy × Clear all
NCT05237960 2026-04-20

Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia

University of Arizona

Phase 2 Active not recruiting
34 enrolled
Head & Neck

Erythroplasia, Leukoplakia, Oral

NCT05536037 2025-05-15

Metformin for the Prevention of Oral Cancer in Patients With Oral Premalignant Lesions

Thomas Jefferson University

Phase 1 Terminated
4 enrolled
Head & Neck

Erythroplasia, Leukoplakia, Mouth Neoplasms

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