Announcements Trials
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Phase

Phase 2 3Phase NA 2Phase 1 2Phase 1/2 1

Status

Withdrawn 1Terminated 1

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Head & Neck 2

Conditions

Neoplasms 2012Carcinoma, Non-Small-Cell Lung 1227Breast Neoplasms 1215Leukemia, Myeloid, Acute 967Neoplasm Metastasis 902Melanoma 777Colorectal Neoplasms 751Multiple Myeloma 725Lymphoma 725Ovarian Neoplasms 675Pancreatic Neoplasms 665Lymphoma, Non-Hodgkin 659Prostatic Neoplasms 657Recurrence 636Precursor Cell Lymphoblastic Leukemia-Lymphoma 585Lung Neoplasms 560Leukemia, Lymphocytic, Chronic, B-Cell 555Glioblastoma 527Leukemia 486Lymphoma, Large B-Cell, Diffuse 440Lymphoma, Follicular 418Brain Neoplasms 414Squamous Cell Carcinoma of Head and Neck 389Stomach Neoplasms 387Carcinoma, Renal Cell 385Myelodysplastic Syndromes 382Carcinoma, Hepatocellular 368Advanced Solid Tumors 357Lymphoma, Mantle-Cell 345Glioma 342

Interventions

Metformin 1Biopsy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1 × Interventional × Erythroplasia × Clear all
NCT05536037 2025-05-15

Metformin for the Prevention of Oral Cancer in Patients With Oral Premalignant Lesions

Thomas Jefferson University

Phase 1 Terminated
4 enrolled
Head & Neck

Erythroplasia, Leukoplakia, Mouth Neoplasms

NCT03939364 2021-10-19

This Study is to Evaluate the Safety and Pharmacokinetics of SBS-101 in Patients With Oral Premalignant Lesions

Skyline Biosciences

Phase 1 Withdrawn
Head & Neck

Erythroplasia, Leukoplakia, Oral

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