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Phase

Phase 1/2 1

Status

Recruiting 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1Other solid neoplasm 1Head & Neck 1Gastrointestinal 1

Conditions

Squamous Cell Carcinoma of Head and Neck 2Carcinoma, Non-Small-Cell Lung 2Triple Negative Breast Neoplasms 1Tracheal Diseases 1Small Cell Lung Carcinoma 1Salivary Gland Neoplasms 1Recurrence 1Pancreatic Neoplasms 1Neuroblastoma 1Neoplasm Metastasis 1Mesothelioma, Malignant 1Mesothelioma 1Lymphoma, Large B-Cell, Diffuse 1Lung Neoplasms 1Laryngeal Diseases 1Head and Neck Neoplasms 1Esophageal Squamous Cell Carcinoma 1Esophageal Neoplasms 1Carcinoma, Adenoid Cystic 1Breast Neoplasms 1Advanced or Metastatic Solid Tumors 1

Interventions

pembrolizumab 27Oxaliplatin 24Paclitaxel 22Fluorouracil 21Carboplatin 18Leucovorin 16Cisplatin 16Capecitabine 16Radiotherapy 15Nivolumab 12Drug Therapy 12Radiation 10Trastuzumab 9Surgical Procedures, Operative 8Immunotherapy 8Magnetic Resonance Spectroscopy 7Esophagectomy 7Blood Specimen Collection 7Taxes 6tislelizumab 5durvalumab 5Surveys and Questionnaires 5Specimen Handling 5Radiotherapy, Intensity-Modulated 5Irinotecan 5Immune Checkpoint Inhibitors 5Docetaxel 5Bevacizumab 5Ramucirumab 4Fluorodeoxyglucose F18 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Esophageal Neoplasms × Combined Modality Therapy × 1 year × Clear all
NCT03556228 2025-12-11

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

VM Oncology, LLC

Phase 1/2 Recruiting
242 enrolled
GastrointestinalHead & NeckOther solid neoplasmThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Adenoid Cystic, Esophageal Neoplasms, Head and Neck Neoplasms, Laryngeal Diseases, Lung Neoplasms, Mesothelioma, Neoplasm Metastasis, Pancreatic Neoplasms, Salivary Gland Neoplasms, Tracheal Diseases, Small Cell Lung Carcinoma

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