Announcements Trials
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Phase

Phase 2 1Phase 1/2 1

Status

Recruiting 1Active not recruiting 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Gastrointestinal 2Thoracic 1Plasma cell 1Other hematologic neoplasm 1Lymphoid 1Head & Neck 1Gynecologic 1Genitourinary 1Dermatologic 1CNS 1Breast 1

Conditions

Breast Neoplasms 76Neoplasm Metastasis 12Neoplasms 8Ovarian Neoplasms 6Endometrial Neoplasms 6Pancreatic Neoplasms 5Carcinoma, Renal Cell 5Sarcoma 4Neoplasms by Site 4Lymphoma, Non-Hodgkin 4Breast Diseases 4Squamous Cell Carcinoma of Head and Neck 3Multiple Myeloma 3Lymphoma 3Lung Neoplasms 3Liposarcoma 3Kidney Neoplasms 3Head and Neck Neoplasms 3Glioma 3Wilms Tumor 2Uterine Cervical Neoplasms 2Triple Negative Breast Neoplasms 2Sarcoma, Ewing 2Rhabdomyosarcoma 2Rhabdoid Tumor 2Recurrence 2Prostatic Neoplasms 2Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Osteosarcoma 2Neuroectodermal Tumors, Primitive, Peripheral 2

Interventions

pembrolizumab 27Oxaliplatin 24Paclitaxel 22Fluorouracil 21Carboplatin 18Leucovorin 16Cisplatin 16Capecitabine 16Radiotherapy 15Nivolumab 12Drug Therapy 12Radiation 10Trastuzumab 9Surgical Procedures, Operative 9Immunotherapy 8Magnetic Resonance Spectroscopy 7Esophagectomy 7Blood Specimen Collection 7Taxes 6tislelizumab 5durvalumab 5Surveys and Questionnaires 5Specimen Handling 5Radiotherapy, Intensity-Modulated 5Irinotecan 5Immune Checkpoint Inhibitors 5Docetaxel 5Bevacizumab 5Ramucirumab 4Fluorodeoxyglucose F18 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Esophageal Neoplasms × palbociclib × 1 year × Clear all
NCT02465060 2026-06-03

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

National Cancer Institute (NCI)

Phase 2 Active not recruiting
6,452 enrolled 1 FDA
BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther hematologic neoplasmPlasma cellThoracic

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Glioma, Carcinoma, Hepatocellular, Lung Neoplasms, Lymphoma, Melanoma, Multiple Myeloma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms, Thyroid Neoplasms, Uterine Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Hematologic Neoplasms

NCT06753747 2025-12-03

A Trial of the Combination of Afatinib and Palbociclib in Previously Treated Advanced Esophageal Squamous Cell Carcinoma

West China Hospital

Phase 1/2 Recruiting
45 enrolled
Gastrointestinal

Esophageal Neoplasms

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