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Phase

Phase 3 1Phase 1/2 1

Status

Completed 42Terminated 9Unknown 4Recruiting 2Active not recruiting 2Not yet recruiting 1

Sponsor Class

INDUSTRY 2

Study Type

Interventional 2

Sponsor

Cancer Type

Gastrointestinal 2

Conditions

Colorectal Neoplasms 34Pancreatic Neoplasms 14Neuroblastoma 13Neoplasm Metastasis 11Stomach Neoplasms 9Neoplasms 8Rectal Neoplasms 5Small Cell Lung Carcinoma 4Esophageal Squamous Cell Carcinoma 4Colonic Neoplasms 4Sarcoma, Ewing 3Rhabdomyosarcoma 3Ovarian Neoplasms 3Gastrointestinal Neoplasms 3Breast Neoplasms 3Adenocarcinoma 3Wilms Tumor 2Sarcoma 2Recurrence 2Osteosarcoma 2Ganglioneuroblastoma 2Esophageal Neoplasms 2Endometrial Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Biliary Tract Neoplasms 2Adenocarcinoma Of Esophagus 2Uterine Neoplasms 1Triple Negative Breast Neoplasms 1Stage I Mixed Cell Type Kidney Wilms Tumor 1Solid Tumors 1

Interventions

pembrolizumab 16Radiotherapy 15Drug Therapy 14Paclitaxel 13Cisplatin 12Carboplatin 10Immunotherapy 9Esophagectomy 9Radiation 8Fluorouracil 8Surgical Procedures, Operative 7Capecitabine 7Blood Specimen Collection 7Oxaliplatin 6Nivolumab 6Immune Checkpoint Inhibitors 6Chemoradiotherapy 6nimotuzumab 5Trastuzumab 5130-nm albumin-bound paclitaxel 5sintilimab 4camrelizumab 4Leucovorin 4trastuzumab deruxtecan 3tislelizumab 3patritumab deruxtecan 3Surveys and Questionnaires 3Endoscopy 3Bevacizumab 3toripalimab 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Recruiting × Esophageal Neoplasms × Irinotecan × Clear all
NCT05319730 2026-05-26

MK-3475-06B

Merck Sharp & Dohme LLC

Phase 1/2 Recruiting
230 enrolled
Gastrointestinal

Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT04415853 2025-05-18

Study of Larotinib in Unresectable Advanced or Recurrent Esophageal Cancer

Sunshine Lake Pharma Co., Ltd.

Phase 3 Recruiting
416 enrolled
Gastrointestinal

Esophageal Neoplasms

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