Clinical Trials

Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms

NCT06380816 2026-05-08

A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer

BreastGastrointestinalGynecologicHead & NeckThoracic

167 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT04908111 2026-04-06

A Trial of ChAdOx1 and MVA Vaccines Against MAGE-A3 and NY-ESO-1

Phase 1/2 Suspended

15 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Lung Neoplasms, Neoplasms, Neoplasms, Squamous Cell

NCT07410676 2026-02-18

EBNK-ST-001

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicOther hematologic neoplasmSarcomaThoracic

83 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Bronchogenic, Disease, Esophageal Neoplasms, Glioblastoma, Kidney Neoplasms, Leukemia, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms

NCT07061704 2025-12-08

Oncolytic Virus in Esophageal Squamous Cell Carcinoma

40 enrolled

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT06753747 2025-12-03

A Trial of the Combination of Afatinib and Palbociclib in Previously Treated Advanced Esophageal Squamous Cell Carcinoma

45 enrolled

Esophageal Neoplasms

NCT05176002 2025-11-19

Camrelizumab in Combination With Radiotherapy for Neoadjuvant Esophageal Carcinoma.

25 enrolled

Esophageal Neoplasms

NCT05057013 2025-08-11

A Phase I/IIa Trial of HMBD-001 in Advanced HER3 Positive Solid Tumours

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

81 enrolled

Lethal Congenital Contracture Syndrome 2, Fibromatosis, Gingival, 2, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Prostatic Neoplasms, Castration-Resistant, Triple Negative Breast Neoplasms

NCT07108855 2025-08-07

BRIGHT

10 enrolled

Esophageal Neoplasms, Stomach Neoplasms

NCT05714553 2025-07-18

NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

19 enrolled

Squamous Cell Carcinoma of Head and Neck, Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Esophageal Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT05944237 2025-06-08

HTL0039732 in Participants With Advanced Solid Tumours

EndocrineGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

150 enrolled

Mesothelioma, Malignant, Urinary Bladder Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Pheochromocytoma, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Prostatic Neoplasms, Castration-Resistant

NCT03212469 2025-05-08

ABIMMUNE

GastrointestinalHead & NeckThoracic

54 enrolled

Squamous Cell Carcinoma of Head and Neck, Esophageal Neoplasms, Lung Neoplasms

NCT05964361 2025-04-25

IL15-TransDC

GastrointestinalGynecologic

10 enrolled

Esophageal Neoplasms, Liver Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms

NCT04166721 2025-04-06

WaKING: Wnt and checKpoint INhibition in Gastric Cancer

52 enrolled

Phase 1/2 Enrolling by invitation

Esophageal Neoplasms, Stomach Neoplasms

NCT06690216 2025-03-30

PD-L1-PET

100 enrolled

CNSGastrointestinalHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Glioblastoma

NCT04278287 2024-12-13

Chemoradiotherapy in Unresectable Esophageal Cancer

105 enrolled

Esophageal Neoplasms

NCT06532799 2024-11-12

BAH250

75 enrolled

Adenocarcinoma, Esophageal Neoplasms, Stomach Neoplasms

NCT03486730 2024-10-24

BT1718 in Patients with Advanced Solid Tumours.

72 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms

NCT05187338 2024-06-25

Triplex Checkpoint Inhibitors Therapy for Advanced Solid Tumors

BreastGastrointestinalGynecologicHead & NeckSarcomaThoracic

100 enrolled

Breast Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms

NCT02735239 2024-03-22

Study of Anti-PD-L1 in Combination With Chemo(Radio)Therapy for Oesophageal Cancer

73 enrolled 18 charts

Adenocarcinoma Of Esophagus, Diabetes Mellitus, Insulin-Dependent, 12, Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT02735057 2024-01-18

OSAGE

54 enrolled

Esophageal Neoplasms

NCT03991104 2023-09-21

SOX-based CRT for Esophageal Cancer.

Phase 1/2 Withdrawn

Esophageal Neoplasms

NCT03544736 2023-03-22

Safety and Feasibility of Irradiation and Nivolumab in Esophageal Cancer (INEC)

30 enrolled

Esophageal Neoplasms

NCT05777707 2023-03-21

Neoadjuvant Therapy of PD-1 Blockade Combined With Chemotherapy for Esophageal Carcinoma

89 enrolled

Esophageal Neoplasms

NCT02999893 2021-12-13

APROC

5 enrolled

Esophageal Neoplasms

NCT00193128 2021-11-24

Preoperative Therapy With Oxaliplatin/Docetaxel/Capecitabine and Radiation in Resectable Esophagus Cancer

59 enrolled 8 charts

Esophageal Neoplasms

NCT01217060 2021-04-13

Trimodality Management of T1b Esophageal Cancers

4 enrolled 8 charts

Adenocarcinoma, Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT02120911 2020-07-01

TRAP

40 enrolled

Esophageal Neoplasms

NCT01128387 2019-12-09

Trial of Panitumumab/Cisplatin/Fluorouracil Combined With Radiation in Esophageal Cancer

11 enrolled 10 charts

Esophageal Neoplasms, Neoplasms

NCT02406170 2019-10-22

REPEAT

47 enrolled

Esophageal Neoplasms, Neoplasm Metastasis, Stomach Neoplasms

NCT02318901 2019-10-21

PembroMab

16 enrolled 6 charts

BreastGastrointestinal

Breast Neoplasms, Esophageal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT02843581 2019-09-12

Combination of Cryosurgery and NK Immunotherapy for Advanced Esophageal Cancer

60 enrolled

Esophageal Neoplasms

NCT03292757 2018-11-19

FLOTOR

21 enrolled

Chylothorax, Esophageal Neoplasms

NCT03706326 2018-10-16

CAR T and PD-1 Knockout Engineered T Cells for Esophageal Cancer

20 enrolled

Esophageal Neoplasms

NCT01231399 2017-05-31

Everolimus and Combination Chemotherapy in Treating Patients With Metastatic Stomach or Esophageal Cancer

6 enrolled 8 charts

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Stomach Neoplasms

NCT02273713 2017-05-31

ACTION

154 enrolled

Esophageal Neoplasms, Neoplasm Metastasis

NCT02762474 2017-02-07

Trial of Concurrent Chemoradiotherapy for Locally Advanced Esophageal Cancer

30 enrolled

Esophageal Neoplasms

NCT03013712 2017-01-06

CARTEPC

GastrointestinalGenitourinary

60 enrolled

Colonic Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Pancreatic Neoplasms, Prostatic Neoplasms, Stomach Neoplasms

NCT00588640 2016-08-10

Study of D-Methadone in Patients With Chronic Pain

BreastCNSGastrointestinalGenitourinaryGynecologicHead & Neck

10 enrolled 6 charts

Urinary Bladder Neoplasms, Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Eye Neoplasms, Head and Neck Neoplasms, Otorhinolaryngologic Neoplasms, Pain, Pancreatic Neoplasms, Prostatic Neoplasms, Uterine Neoplasms, Central Nervous System Neoplasms

NCT00544362 2016-05-30

Fluorouracil, Cisplatin, Cetuximab, and Radiation Therapy in Treating Patients With Esophageal Cancer That Can Be Removed by Surgery

33 enrolled

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT00504322 2016-05-04

cd40

Phase 1/2 Withdrawn

Esophageal Neoplasms

NCT02693236 2016-02-26

DC Vaccine Combined With CIK Cells in Patients With Esophagus Cancer

30 enrolled

Esophageal Neoplasms

NCT00130936 2016-02-15

Study of Epirubicin (Pharmorubicin®), Carboplatin (Paraplatin®) and Capecitabine (Xeloda®) (ECC) in the Treatment of Unresectable Locally Advanced or Metastatic Gastric/Gastroesophageal Junction Cancer With Pharmacogenetic Correlates

50 enrolled

Esophageal Neoplasms, Neoplasms, Stomach Neoplasms

NCT00093652 2015-10-06

Oxaliplatin, Gefitinib, and Radiation Therapy in Treating Patients With Locally Advanced or Metastatic Esophageal Cancer

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT00578071 2015-07-02

POXX

29 enrolled 10 charts

Esophageal Neoplasms

NCT00374985 2014-12-02

Safety and Efficacy of Neoadjuvant Radiochemotherapy in Adenocarcinoma of the Gastric-oesophageal Junction

25 enrolled

Esophageal Neoplasms, Stomach Neoplasms

NCT00425425 2014-05-01

Cetuximab, Oxaliplatin, Fluorouracil, and Radiation Therapy in Treating Patients With Stage II or Stage III Esophageal Cancer

43 enrolled

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT00003103 2013-07-03

Chemotherapy in Treating Patients With Solid Tumors

BreastCNSGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

57 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Lung Neoplasms, Wilms Tumor, Ovarian Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Esthesioneuroblastoma, Olfactory

NCT01843049 2013-04-30

Dose Escalation by Boosting Radiation Dose Within the Primary Tumor Using 18FDG-PET/CT for Unresectable Thoracic Esophageal Cancer

40 enrolled

Esophageal Neoplasms

NCT00722605 2013-01-24

Multiple Respiration-Correlated Cone Beam Computed Tomography (CT) Scans to Reduce Target Positioning Errors in Radiotherapy Treatment of Thoracic Cancer