Clinical Trials

147 enrolled

Adenocarcinoma, Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT03161522 2026-04-15

Chemotherapy With or Without Radiation or Surgery in Treating Participants With Oligometastatic Esophageal or Gastric Cancer

100 enrolled

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Stomach Neoplasms

NCT03948100 2026-04-15

Dyadic Yoga Intervention in Improving Physical Performance and Quality of Life in Patients With Stage I-IV Non-small Cell Lung or Esophageal Cancer Undergoing Radiotherapy and Their Caregivers

400 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Lung Neoplasms

NCT07519486 2026-04-15

INS-ESCC-CT

118 enrolled

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT07530094 2026-04-15

STELLAR01

98 enrolled

Phase 2 Not yet recruiting

Esophageal Neoplasms

NCT07530549 2026-04-15

A Phase II Single-arm Clinical Study in the Treatment of Locally Advanced Esophageal Cancer After Failed Neoadjuvant Chemoimmunotherapy

40 enrolled

GastrointestinalHead & NeckThoracic

Esophageal Neoplasms

NCT03102229 2026-04-13

RAMPART

Phase NA Completed

40 enrolled

Esophageal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Stomach Neoplasms

NCT05450484 2026-04-13

OPTIC

Phase 1 Completed

21 enrolled

Phase NA Not yet recruiting

Esophageal Neoplasms

NCT07518680 2026-04-08

A Clinical Study on the Effect of Massaging Tian Tu Acupoint on Coughing After Esophageal Surgery

Esophageal Neoplasms

NCT03764553 2026-04-07

LyRICX

320 enrolled

Esophageal Neoplasms

NCT07283939 2026-04-07

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

420 enrolled

Appendiceal Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT00213486 2026-04-06

Weekly Cisplatin/Irinotecan and Radiotherapy in Patients With Locally Advanced Esophageal Cancer: Phase II Trial

Phase 2 Completed

43 enrolled

Esophageal Neoplasms

NCT04908111 2026-04-06

A Trial of ChAdOx1 and MVA Vaccines Against MAGE-A3 and NY-ESO-1

Phase 1/2 Suspended

15 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Lung Neoplasms, Neoplasms, Neoplasms, Squamous Cell

NCT06275737 2026-04-06

POP-UP

9 enrolled

Esophageal Neoplasms

NCT03482791 2026-04-02

Proton Beam Therapy in the Treatment of Esophageal Cancer

22 enrolled 29 charts

Esophageal Neoplasms

NCT05480384 2026-04-01

Adjuvant Trastuzumab Deruxtecan (Enhertu) & Nivolumab For Patients Who Are Disease Free After Completion of Trimodality Treatment For HER-2+ Cancers of Esophagus & Gastroesophageal Junction

1 enrolled

Phase NA Not yet recruiting

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT07187154 2026-04-01

The Application of Symptoms Management Program Based on the Patient Reported Outcome After Esophagectomy

252 enrolled

Esophageal Neoplasms

NCT05145647 2026-03-27

To Observe the Benefit of Adding Brachytherapy After CCRT on Resectable Esophageal Cancer Patients Without Surgery

18 enrolled

Phase 1 Active not recruiting

Esophageal Neoplasms

NCT03044613 2026-03-23

Nivolumab +/- Relatlimab Prior to Chemoradiation With II/III Gastro/Esophageal Cancer

32 enrolled

Esophageal Neoplasms, Stomach Neoplasms

NCT06792786 2026-03-23

A Multicenter Prospective Study Evaluating Concurrent Chemoradiotherapy Following Induction Immunochemotherapy for Esophageal Cancer Based on Dynamic ctDNA Monitoring

BreastGastrointestinalGynecologicThoracic

Esophageal Neoplasms

NCT05143970 2026-03-20

CHANCES

Phase 1 Recruiting

27 enrolled

Breast Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Endometrial Neoplasms

NCT02359968 2026-03-18

PROTECT

Phase 2 Completed

106 enrolled

Esophageal Neoplasms

NCT02642809 2026-03-18

Pembrolizumab With Locally Delivered Radiation Therapy for the Treatment of Metastatic Esophageal Cancers

Phase 1 Completed

16 enrolled 13 charts

Esophageal Neoplasms

NCT04674267 2026-03-18

REACH

257 enrolled

Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT05187182 2026-03-18

CA-4948 in Combination With FOLFOX/PD-1 Inhibitor +/- Trastuzumab for Untreated Unresectable Gastric and Esophageal Cancer

Phase 1 Recruiting

42 enrolled

Phase 1 Not yet recruiting

Esophageal Neoplasms, Stomach Neoplasms

NCT06735638 2026-03-18

Outside the Cage (OTC) Robotic Esophagectomy

31 enrolled

Esophageal Neoplasms, Ornithine Carbamoyltransferase Deficiency Disease

NCT06652620 2026-03-16

Cola Ingestion for Esophageal Bolus Impaction

50 enrolled

Esophageal Neoplasms

NCT07132918 2026-03-11

HEARTS Trial for Thoracic Cancers

60 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Thymoma

NCT07175155 2026-03-11

Combination of COMBO Endoscopy Oropharyngeal Airway and HFNC Oxygenation in Sedated Gastrointestinal Endoscopy for Morbidly Obese Patients

410 enrolled

Hypoxia, Esophageal Neoplasms, Stomach Neoplasms

NCT06408116 2026-03-10

PEGASUS

Esophageal Neoplasms

NCT07460596 2026-03-10

Concentrated Complex Plant Dietary Elements for Chemotherapy-Induced Diarrhea

Phase 2 Completed

Esophageal Neoplasms, Rectal Neoplasms

NCT05183126 2026-03-06

Pharmacokinetic Study of Skeletal Muscle Area-based Paclitaxel Infusion in Patients With Cancer

Phase 4 Recruiting

22 enrolled

BreastGastrointestinal

Breast Neoplasms, Esophageal Neoplasms, Stomach Neoplasms

NCT07070466 2026-03-06

Ivonescimab in Comb. With FOLFOX in Advanced HER2 Neg. GEA

40 enrolled

Esophageal Neoplasms, Stomach Neoplasms

NCT07455019 2026-03-06

A Study of Bemosubaiabimab Combined With Anlotinib and Radiotherapy and Chemotherapy for the Treatment of Oligometastatic Esophageal Cancer

28 enrolled

Esophageal Neoplasms

NCT04757363 2026-03-04

A Study of Nivolumab Combined With FOLFOX and Regorafenib in People Who Have HER2-Negative Esophagogastric Cancer

39 enrolled

Esophageal Neoplasms

NCT03403465 2026-02-27

Intratreatment FDG-PET During Radiation Therapy for Gynecologic and Gastrointestinal Cancers

GastrointestinalGynecologic

90 enrolled

Anal Canal Carcinoma, Uterine Cervical Neoplasms, Esophageal Neoplasms, Vulvar Neoplasms

NCT06452602 2026-02-27

Induction Immunochemotherapy Followed by Concurrent Chemoradiotherapy in Patients With ESCC.

60 enrolled

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT07307560 2026-02-27

High-Flow Nasal Cannula for Preventing Hypoxia During Sedated Endoscopy in High-Risk Obstructive Sleep Apnea Patients

600 enrolled

Phase NA Not yet recruiting

Hypoxia, Disease, Esophageal Neoplasms, Stomach Neoplasms, Sleep Apnea, Obstructive

NCT07434739 2026-02-27

PACEMIE

506 enrolled

Esophageal Neoplasms

NCT07435454 2026-02-27

Exploratory Clinical Trial of Oral Paclitaxel Plus Radiotherapy in Patients With Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma

22 enrolled

Esophageal Neoplasms

NCT06523374 2026-02-24

Endeavor-1

50 enrolled

Adenocarcinoma Of Esophagus, Barrett Esophagus, Esophageal Neoplasms

NCT03174275 2026-02-23

Carboplatin, Nab-Paclitaxel, Durvalumab Before Surgery and Adjuvant Therapy in Head and Neck Squamous Cell Carcinoma

GastrointestinalHead & Neck

39 enrolled 8 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Esophageal Neoplasms, Laryngeal Neoplasms, Lip Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT04258813 2026-02-20

ONE TEAM

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

313 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Cardiovascular Diseases, Colonic Neoplasms, Diabetes Mellitus, Esophageal Neoplasms, Head and Neck Neoplasms, Hypercholesterolemia, Hypertension, Liver Neoplasms, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Endometrial Neoplasms

NCT04907643 2026-02-20

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

EndocrineGastrointestinalNET

360 enrolled

Cancer Pain, Anus Neoplasms, Appendiceal Neoplasms, Bile Duct Neoplasms, Biliary Tract Neoplasms, Carcinoid Tumor, Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Liver Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Rectal Neoplasms, Recurrence, Stomach Neoplasms, Neuroendocrine Tumors, Visceral Pain

NCT03896399 2026-02-19

ISCON

Phase NA Completed

22 enrolled

Esophageal Neoplasms

NCT06346080 2026-02-18

MAGECmultiDiCE

2,200 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicOther hematologic neoplasmSarcomaThoracic

Esophageal Neoplasms, Stomach Neoplasms

NCT07410676 2026-02-18

EBNK-ST-001

Phase 1/2 Recruiting

83 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Bronchogenic, Disease, Esophageal Neoplasms, Glioblastoma, Kidney Neoplasms, Leukemia, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms

NCT07416825 2026-02-18

Inter-Observer Delineation Differences in Esophageal Cancer GTV on MR, CT, and PET/CT Protokol šečerov Ermenc 28dec19

Phase NA Completed

23 enrolled

Esophageal Neoplasms

NCT06346054 2026-02-17

MAGEC

1,000 enrolled