Clinical Trials

35 enrolled

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT00937456 2026-04-22

Open Versus Laparoscopically-assisted Esophagectomy for Cancer

207 enrolled

Esophageal Neoplasms, Neoplasms

NCT03102229 2026-04-13

RAMPART

GastrointestinalHead & NeckThoracic

40 enrolled

Esophageal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Stomach Neoplasms

NCT05450484 2026-04-13

OPTIC

21 enrolled

Esophageal Neoplasms

NCT04540211 2026-04-09

SKYSCRAPER-08

Phase 3 Completed

461 enrolled 24 charts

Esophageal Neoplasms

NCT00213486 2026-04-06

Weekly Cisplatin/Irinotecan and Radiotherapy in Patients With Locally Advanced Esophageal Cancer: Phase II Trial

43 enrolled

Esophageal Neoplasms

NCT02359968 2026-03-18

PROTECT

106 enrolled

Esophageal Neoplasms

NCT02642809 2026-03-18

Pembrolizumab With Locally Delivered Radiation Therapy for the Treatment of Metastatic Esophageal Cancers

16 enrolled 13 charts

Esophageal Neoplasms

NCT07460596 2026-03-10

Concentrated Complex Plant Dietary Elements for Chemotherapy-Induced Diarrhea

30 enrolled

Esophageal Neoplasms, Rectal Neoplasms

NCT04426669 2026-02-23

A Study of Metastatic Gastrointestinal Cancers Treated With Tumor Infiltrating Lymphocytes in Which the Gene Encoding the Intracellular Immune Checkpoint CISH Is Inhibited Using CRISPR Genetic Engineering

23 enrolled

Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT03896399 2026-02-19

ISCON

22 enrolled

Esophageal Neoplasms

NCT07416825 2026-02-18

Inter-Observer Delineation Differences in Esophageal Cancer GTV on MR, CT, and PET/CT Protokol šečerov Ermenc 28dec19

23 enrolled

Esophageal Neoplasms

NCT03993353 2026-02-12

Tadalafil and Pembrolizumab in Recurrent or Metastatic Head and Neck Cancer

GastrointestinalHead & Neck

7 enrolled 14 charts

Pyridoxine-dependent epilepsy, Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Esophageal Neoplasms, Head and Neck Neoplasms, Mouth Neoplasms, Neoplasm Metastasis, Neoplasms

NCT06027515 2026-02-12

Esophageal Cancer Multimodal Prehabilitation Study

15 enrolled

Esophageal Neoplasms

NCT00628368 2026-02-10

Biological Factors in Predicting Response to Treatment in Patients With Esophageal Cancer or Rectal Cancer

160 enrolled

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT04217239 2026-02-05

A Comparison Between Ivor-Lewis and McKeown Minimally Invasive Esophagectomy

272 enrolled

Esophageal Neoplasms

NCT03008278 2026-02-03

Olaparib and Ramucirumab in Treating Patients With Metastatic or Locally Recurrent Gastric or Gastroesophageal Junction Cancer That Cannot Be Removed by Surgery

51 enrolled 20 charts

Esophageal Neoplasms, Stomach Neoplasms

NCT04505553 2026-01-21

Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer

EndocrineGastrointestinalNET

78 enrolled 14 charts

Gastro-enteropancreatic neuroendocrine tumor, Anus Neoplasms, Appendiceal Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Carcinoma, Hepatocellular, Adenoma, Islet Cell, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT03611309 2026-01-08

PERIOP-PC

379 enrolled 15 charts

Esophageal Neoplasms, Gastrointestinal Neoplasms, Liver Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT03246516 2025-12-23

DELOGAST

258 enrolled

Esophageal Neoplasms

NCT05342636 2025-12-17

A Study of Combination Therapies With or Without Pembrolizumab (MK-3475) and/or Chemotherapy in Participants With Advanced Esophageal Cancer (MK-3475-06A)

90 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT03281369 2025-12-15

A Study of Multiple Immunotherapy-Based Treatment Combinations in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Cancer (G/GEJ) or Esophageal Cancer (Morpheus-Gastric and Esophageal Cancer)

214 enrolled

Esophageal Neoplasms

NCT05795595 2025-11-26

A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed or Refractory Solid Tumors

GastrointestinalGenitourinaryGynecologicOther solid neoplasmThoracic

19 enrolled

Mesothelioma, Malignant, Carcinoma, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms

NCT07155330 2025-11-25

High-flow Nasal Cannula Oxygenation in Sedated Endoscopy for High-risk Obstructive Sleep Apnea Patients

80 enrolled

Hypoxia, Colonic Neoplasms, Disease, Esophageal Neoplasms, Stomach Neoplasms, Sleep Apnea, Obstructive

NCT03777813 2025-11-18

ARION

112 enrolled

Adenocarcinoma, Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT05383482 2025-11-17

Afuresertib +Sintilimab+Chemotherapy in Patients With Selected Solid Tumors That Resistance to Prior Anti-PD-1/PD-L1

GastrointestinalGynecologic

22 enrolled

Uterine Cervical Neoplasms, Esophageal Neoplasms, Endometrial Neoplasms

NCT06129487 2025-11-14

Evaluations of Alcohol Warning Labels

GastrointestinalHead & Neck

1,053 enrolled 15 charts

Alcohol Drinking, Esophageal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms

NCT01191697 2025-11-03

CAPOX, Bevacizumab and Trastuzumab for Patients With HER2-Positive Metastatic Esophagogastric Cancer

37 enrolled 11 charts

Esophageal Neoplasms, Stomach Neoplasms

NCT04526886 2025-10-06

Clinical Trial of a Novel Dose Adjustment Algorithm for Preventing Cytopenia-Related Delays During FOLFOX Chemotherapy

Classical hematologyGastrointestinal

52 enrolled 8 charts

Appendiceal Neoplasms, Esophageal Neoplasms, Neutropenia, Stomach Neoplasms, Thrombocytopenia, Colorectal Neoplasms

NCT02558504 2025-10-02

HARMONI

Phase 4 Completed

87 enrolled

Esophageal Neoplasms

NCT03929666 2025-09-12

A Safety and Efficacy Study of ZW25 (Zanidatamab) Plus Combination Chemotherapy in HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer

74 enrolled

Biliary Tract Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT00924027 2025-09-05

A Study of Patients Receiving High-Dose Rate Brachytherapy

GastrointestinalGenitourinaryGynecologic

43 enrolled 13 charts

Biliary Tract Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Neoplasms, Prostatic Neoplasms, Endometrial Neoplasms

NCT02415101 2025-09-03

NeoResII

202 enrolled

Adenocarcinoma, Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT04772989 2025-08-28

ARC-12

DermatologicGastrointestinalGynecologicLymphoidPlasma cellThoracic

94 enrolled

Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Lymphoma, Non-Hodgkin, Melanoma, Multiple Myeloma, Stomach Neoplasms, Lymphoma, Large B-Cell, Diffuse

NCT06582849 2025-08-26

EARN

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther hematologic neoplasmSarcomaThoracic

33 enrolled

Anus Neoplasms, Urinary Bladder Neoplasms, Bone Neoplasms, Brain Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Lymphoma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Penile Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Thyroid Neoplasms, Uterine Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms

NCT05007106 2025-08-14

KEYVIBE-005

BreastGastrointestinalGenitourinaryGynecologicHead & Neck

613 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Ovarian Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma, Triple Negative Breast Neoplasms

NCT00680901 2025-08-07

LOGiC - Lapatinib Optimization Study in ErbB2 (HER2) Positive Gastric Cancer: A Phase III Global, Blinded Study Designed to Evaluate Clinical Endpoints and Safety of Chemotherapy Plus Lapatinib

Phase 3 Completed

545 enrolled 24 charts

Esophageal Neoplasms, Neoplasm Metastasis, Neoplasms

NCT06275165 2025-08-07

The Effects of Acupressure on Improving Postoperative Gastrointestinal Symptom Distress in Esophageal Cancer Patients

48 enrolled

Esophageal Neoplasms

NCT02013154 2025-08-03

P102

151 enrolled

Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT02534233 2025-08-01

ColdPlay2

58 enrolled 10 charts

Barrett Esophagus, Esophageal Neoplasms

NCT03199586 2025-07-20

Clinical Trial of Metastasis Inhibitor NP-G2-044 in Patients With Advanced or Metastatic Treatment-Refractory Solid Tumor Malignancies

BreastGastrointestinalGenitourinaryGynecologicThoracic

23 enrolled

Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Liver Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms

NCT06048913 2025-07-04

Nimotuzumab Combined With Concurrent Chemoradiotherapy for Locally Advanced Treatment Esophageal Cancer in Old Age

56 enrolled

Esophageal Neoplasms

NCT06812403 2025-06-25

Combination COMBO Endoscopy Oropharyngeal Airway With High-Flow Nasal Cannula Oxygenation in Sedated Gastrointestinal Endoscopy for Obese Patients

50 enrolled

Hypoxia, Colonic Polyps, Esophageal Neoplasms, Stomach Neoplasms

NCT05788484 2025-06-15

A Study of CDX-585 in Patients With Advanced Malignancies

GastrointestinalGenitourinaryGynecologicHead & NeckThoracic

20 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Esophageal Neoplasms, Fallopian Tube Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT05405530 2025-06-05

NASO

1,204 enrolled