Clinical Trials Browser

Not yet recruiting × Esophageal Neoplasms × Clear all

NCT07603375 2026-05-22

TNT Esophagus

Phase 2 Not yet recruiting

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT07605312 2026-05-22

AI-Based Risk Prediction Model for Upper Digestive Tract Cancer

Not yet recruiting

10,000 enrolled

Gastrointestinal

Esophageal Neoplasms, Gastritis, Atrophic, Stomach Neoplasms

NCT07594626 2026-05-19

BMS-986504 in Combination With Pemetrexed for the Treatment of Metastatic Solid Tumors With MTAP Deletion

Phase 1/2 Not yet recruiting

Gastrointestinal

Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms

NCT07596732 2026-05-19

SUNRISE

Phase NA Not yet recruiting

GastrointestinalThoracic

Colonic Neoplasms, Disease, Esophageal Neoplasms, Lung Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT07583316 2026-05-13

A Phase 1 First-in-Human Study of CRPA1A2, a MAGE-A1/HLA-A*02:01 Bispecific T-Cell Engager, in Patients With Solid Tumors

Phase 1 Not yet recruiting

GastrointestinalHead & NeckThoracic

Esophageal Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Lung Neoplasms, Neoplasm Metastasis

NCT07573397 2026-05-07

A Prospective Study of Tumor-specific Tpex in Negative Lymph Nodes for Predicting Pathological Complete Response to Neoadjuvant PD 1 Therapy in Esophageal Cancer

Not yet recruiting

Gastrointestinal

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT07565857 2026-05-04

SIGNAL GEC-101

Phase NA Not yet recruiting

Gastrointestinal

Esophageal Neoplasms, Stomach Neoplasms

NCT07365124 2026-04-30

MRinRT

Not yet recruiting

CNSGastrointestinal

Carcinoma, Esophageal Neoplasms, Glioblastoma, Neoplasms, Neurologic Manifestations, Pancreatic Neoplasms, Stomach Neoplasms

NCT07533357 2026-04-16

Tpex Subsets in Negative Tumor Draining Lymph Nodes for Predicting the Efficacy of PD 1 Inhibitors in Advanced or Recurrent Esophageal Squamous Cell Carcinoma

Not yet recruiting

Gastrointestinal

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT07530549 2026-04-15

A Phase II Single-arm Clinical Study in the Treatment of Locally Advanced Esophageal Cancer After Failed Neoadjuvant Chemoimmunotherapy

Phase 2 Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT07518680 2026-04-08

A Clinical Study on the Effect of Massaging Tian Tu Acupoint on Coughing After Esophageal Surgery

Phase NA Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT07187154 2026-04-01

The Application of Symptoms Management Program Based on the Patient Reported Outcome After Esophagectomy

Phase NA Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT06735638 2026-03-18

Outside the Cage (OTC) Robotic Esophagectomy

Phase 1 Not yet recruiting

Gastrointestinal

Esophageal Neoplasms, Ornithine Carbamoyltransferase Deficiency Disease

NCT07434739 2026-02-27

PACEMIE

Phase NA Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT07440212 2026-02-27

Clinical Study on Noninvasive Evaluation of Ivonescimab Antibody Distribution and Expression in Esophageal Cancer Patients by 89Zr-AK112 PET Imaging

Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT07406815 2026-02-12

The Value of Near-Infrared Fluorescence Imaging in the Protection of the Recurrent Laryngeal Nerve During Minimally Invasive Esophagectomy

Phase 3 Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT07392775 2026-02-06

ALDH2 Genetic Testing in East Asian Community

Phase NA Not yet recruiting

Gastrointestinal

Alzheimer Disease, Cardiovascular Diseases, Esophageal Neoplasms, Flushing

NCT07382635 2026-02-03

Clinical Trial Protocol for Evaluating the Efficacy and Safety of Thoracoabdominal Endoscopic Surgery System in Remote Laparoscopic Surgery for Urology, General Surgery, Gynecology and Thoracic Surgery

Not yet recruiting

Gastrointestinal

Esophageal Neoplasms, Colorectal Neoplasms

NCT07376876 2026-01-29

Indocyanine Green-guided Omental Shield Anastomosis for Cervical Esophagogastric Anastomosis in Minimally Invasive McKeown Esophagectomy

Phase 2 Not yet recruiting

Gastrointestinal

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms, Anastomotic Leak

NCT07341737 2026-01-15

SL-28 for Advanced Solid Tumours

Phase 1/2 Not yet recruiting

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Adenocarcinoma of Lung, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Head and Neck Neoplasms, Intestinal Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT07332221 2026-01-12

Application of Toripalimab as Adjuvant Therapy After Esophageal Cancer Surgery: A Multicenter Clinical Trial

Phase 3 Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT07330583 2026-01-09

Stereotactic Body Radiation Therapy (SBRT) and Immunotherapy for Oligometastatic Esophageal Cancer

Phase 2 Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT07324018 2026-01-08

Spirulina Derivative for Radiation Esophagitis

Phase 2 Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT07303231 2025-12-24

The Value of Indocyanine Green-guided Near-infrared Fluorescence Technology in Tracing Sentinel Lymph Nodes During Esophagectomy

Phase 3 Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT07283991 2025-12-16

BRICES

Phase 2 Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT06914011 2025-12-03

MRD2START

Phase 3 Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT07260734 2025-12-03

AROMA2

Not yet recruiting

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT07196384 2025-11-21

GLOW

Phase 1 Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT07233850 2025-11-18

A Phase II Clinical Study Evaluating SSGJ-706 in Combination Therapy for Advanced Gastrointestinal Cancers

Phase 2 Not yet recruiting

Gastrointestinal

Esophageal Neoplasms, Colorectal Neoplasms

NCT07222657 2025-10-31

Liquid Nitrogen Spray Cryotherapy Prior to Neoadjuvant Systemic Therapy in Esophageal Adenocarcinoma

Phase 2 Not yet recruiting

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT07211009 2025-10-07

Patient-Reported Symptom Care Versus Usual Care After Esophageal Cancer Surgery: A Single-Center Phase 3 Randomized Trial

Phase 3 Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT07203690 2025-10-02

Development and Application of AI-Based Therapeutic Strategies for Esophageal Cancer Integrating Multimodal Imaging and Digital Pathology

Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT07104838 2025-09-25

Non-intubated Versus Intubated Anesthesia in Thoracoscopic Esophagectomy for Esophageal Cancer

Phase NA Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT07180134 2025-09-18

Health Informatics and Resistance Exercise for Symptom Management and Quality of Life in Post-Esophagectomy Patients

Phase NA Not yet recruiting

Gastrointestinal

Esophageal Neoplasms, Motor Activity, Sarcopenia

NCT07176052 2025-09-16

Expectation, Pain Outcomes, and Pain Medication Following Oncology Abdominal Surgery: A Cohort Study

Not yet recruiting

Gastrointestinal

Esophageal Neoplasms, Liver Neoplasms, Pancreatic Neoplasms, Acute Pain

NCT07159711 2025-09-08

SEISMIC

Not yet recruiting

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT07154108 2025-09-04

Endostatin Adenovirus With Checkpoint Inhibitor in Advanced Head and Neck or Esophageal Cancer

Phase 1 Not yet recruiting

GastrointestinalHead & Neck

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms, Head and Neck Neoplasms

NCT07046221 2025-07-20

Tislelizumab Combined With Chemotherapy for Resectable Esophageal Squamous Cell Carcinoma Followed by CRT or Surgery

Phase 2 Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT07067359 2025-07-16

INSECNT

Phase NA Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT07064655 2025-07-15

Non-gastric Conduit Reconstruction After Esophagectomy

Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT07034118 2025-06-24

Definitive Proton Radiotherapy Combined With Chemotherapy and Immunotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma: A Phase I Clinical Study

Phase 1 Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT07019181 2025-06-13

Tislelizumab Combined With Chemotherapy for the Perioperative Treatment of Esophageal Squamous Carcinoma

Phase 2 Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT06986291 2025-05-29

CorTox

Phase NA Not yet recruiting

BreastGastrointestinalThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Cardiotoxicity

NCT06876454 2025-05-25

Optimal Nutritional Palliation of Obstructed GEJ Cancer

Phase NA Not yet recruiting

Gastrointestinal

Esophageal Neoplasms, Neoplasm Metastasis

NCT06979986 2025-05-20

SLND Versus Non-Dissection Following ESD for T1a Stage Esophageal Squamous Cell Carcinoma

Phase NA Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT05048368 2025-05-18

Pharmacokinetics Study of Larotinib in Subjects With Impaired Hepatic Function

Phase 1 Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT06965205 2025-05-11

Use of Different Enteral Feeds to Impact on Chyle Leaks in Oesophagectomy

Phase NA Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT06965829 2025-05-11

The Effect of Neoadjuvant Chemoimmnotherapy Combined With Node Sparing Radiotherapy for cT3N+ EC

Phase 2 Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT05041335 2025-04-22

EUS Heparin

Phase NA Not yet recruiting

Gastrointestinal

Esophageal Neoplasms, Liver Neoplasms, Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT06933966 2025-04-18

ATTENUATION

Phase 2 Not yet recruiting

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Neoplasms