Clinical Trials

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckNETOther hematologic neoplasmOther solid neoplasmPlasma cellSarcomaThoracic

999,999 enrolled

Anus Neoplasms, Bile Duct Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Colonic Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, Duodenal Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Hypopharyngeal Neoplasms, Kidney Neoplasms, Laryngeal Neoplasms, Leukemia, Lip Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Mesothelioma, Mouth Neoplasms, Multiple Myeloma, Nasopharyngeal Neoplasms, Neoplasms, Unknown Primary, Oropharyngeal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Paranasal Sinus Neoplasms, Paraproteinemias, Penile Neoplasms, Peritoneal Neoplasms, Adenomatous Polyposis Coli, Prostatic Neoplasms, Rectal Neoplasms, Salivary Gland Neoplasms, Sarcoma, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Thymus Neoplasms, Thyroid Neoplasms, Ureteral Neoplasms, Urethral Neoplasms, Vaginal Neoplasms, Central Nervous System Neoplasms, Thyroid Nodule, Endometrial Neoplasms, Neuroendocrine Tumors, Gastrointestinal Stromal Tumors

NCT00242723 2026-05-01

Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining

GastrointestinalOther solid neoplasmThoracic

1,559 enrolled

Mesothelioma, Malignant, Esophageal Neoplasms, Lung Neoplasms

NCT02838836 2026-05-01

Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers

620 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Liver Neoplasms, Neoplastic Cells, Circulating, Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT07124000 2026-05-01

DP-04

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

Adenocarcinoma, Anus Neoplasms, Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Melanoma, Mouth Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Sarcoma, Testicular Neoplasms, Thyroid Neoplasms, Urethral Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Endometrial Neoplasms, Gastrointestinal Stromal Tumors, Small Cell Lung Carcinoma

NCT06440174 2026-04-30

VALUE

160 enrolled

Esophageal Neoplasms

NCT06713993 2026-04-24

Semmelweis Esophageal Cancer Study: Noninvasive Prognostic Parameters in Patients With Oesophageal and Esophagogastric Junction Cancer

Frailty, Esophageal Neoplasms, Heart Failure, Cardiovascular Abnormalities, Malnutrition, Sarcopenia

NCT00260559 2026-04-14

Outcomes After Esophagectomy With a Focus on Minimally Invasive Esophagectomy and Quality of Life

3,500 enrolled

Esophageal Neoplasms

NCT00260585 2026-04-14

Esophageal Cancer Risk Registry

7,000 enrolled

Esophageal Achalasia, Esophageal Diseases, Esophageal Neoplasms, Gastroesophageal Reflux, Hernia, Hiatal

NCT02530983 2026-03-30

UDD

1,000 enrolled

Digestive System Abnormalities, Esophageal Neoplasms

NCT06447064 2026-03-25

(CLOCS-2)

GastrointestinalGenitourinaryGynecologic

2,900 enrolled

Urinary Bladder Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Liver Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Uterine Neoplasms, Vulvar Neoplasms, Endometrial Neoplasms

NCT06476678 2026-03-25

Novel Bipolar Radiofrequency Ablation Knife in Esophageal Lesions

50 enrolled

Esophageal Neoplasms

NCT06343597 2026-03-20

Volume Outcome Relationships and Effects

30 enrolled

Esophageal Neoplasms

NCT06349642 2026-03-12

ELEPHAS-04

DermatologicGastrointestinalGenitourinaryGynecologicSarcomaThoracic

324 enrolled

Clear-cell metastatic renal cell carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinosarcoma, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Neoplasm Metastasis, Skin Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT07464470 2026-03-12

GENCONCOR-2

30 enrolled

CNSGastrointestinal

Brain Neoplasms, Esophageal Neoplasms, Stomach Neoplasms

NCT07104214 2026-03-11

Development and Validation of a Risk Prediction Model for Gastric Retention in Patients Undergoing Sedated Gastroscopy

5,000 enrolled

Esophageal Neoplasms, Gastroparesis

NCT07354295 2026-03-10

Integrating Multimodal AI to Predict Treatment Response and Refine Risk Stratification in Esophageal Cancer （Radiogenomics-Esophagus）

1,500 enrolled

Esophageal Neoplasms

NCT05706558 2026-03-09

Retrospective Review of Esophageal Cancer at MSKCC

4,000 enrolled

Esophageal Neoplasms

NCT00899626 2026-03-05

Gastrointestinal Biomarkers in Tissue and Biological Fluid Samples From Colorectal Cancer Patients

GastrointestinalOther neoplasm

5,000 enrolled

Colonic Neoplasms, Esophageal Neoplasms, Pancreatic Neoplasms, Precancerous Conditions, Stomach Neoplasms, Colorectal Neoplasms, Adenomatous Polyps

NCT04075305 2026-03-05

MOMENTUM

BreastCNSGastrointestinalGenitourinaryHead & NeckThoracic

8,000 enrolled

Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Esophageal Neoplasms, Genital Neoplasms, Female, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Radiation Injuries, Rectal Neoplasms

NCT04354064 2026-02-20

Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

BreastDermatologicGastrointestinalGenitourinaryHead & NeckSarcomaThoracic

Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Prostatic Neoplasms, Sarcoma, Skin Neoplasms, Urogenital Neoplasms

NCT05366881 2026-01-20

CAMPERR

BreastCNSGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther hematologic neoplasmPlasma cellSarcomaThoracic

7,000 enrolled

Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Leukemia, Lung Neoplasms, Lymphoma, Multiple Myeloma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT06787313 2026-01-13

Precision Palliative Care for Patients With Advanced Esophageal Cancer

624 enrolled

Esophageal Neoplasms

NCT07322627 2026-01-07

ALDH2 Single Nucleotide Polymorphisms and Prognosis of Esophageal Cancer Patients

700 enrolled

Esophageal Neoplasms

NCT00991094 2026-01-02

Data Collection for the Assessment of Acute and Late Normal Tissue in Patients Treated With Proton Therapy

BreastCNSGastrointestinalOther hematologic neoplasmThoracic

5,000 enrolled

Breast Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Lung Neoplasms, Central Nervous System Neoplasms, Hematologic Neoplasms

NCT07301814 2025-12-24

Clinical Application of PET Imaging Targeting CLDN18.2 in Malignant Tumors

56 enrolled

Esophageal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT01048281 2025-12-18

Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma

GastrointestinalSarcoma

Esophageal Neoplasms, Stomach Neoplasms, Gastrointestinal Stromal Tumors

NCT04214119 2025-12-16

EsophaCap for the Detection of Early Esophageal Carcinoma

2,500 enrolled

Barrett Esophagus, Esophageal Neoplasms, Stomach Neoplasms

NCT06979869 2025-12-16

Investigating Multigene Methylation Dynamics in Treatment Response Surveillance for Esophageal Carcinoma

300 enrolled

Esophageal Neoplasms

NCT05642819 2025-12-02

REVOLUTION Surgery (REVOLUTION Surgery)

200 enrolled

Cachexia, Esophageal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT06097078 2025-11-17

ESPY

44 enrolled

Esophageal Neoplasms, Anastomotic Leak

NCT03452774 2025-10-28

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidMyeloidNETOther hematologic neoplasmThoracic

50,000 enrolled

Turcot syndrome, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Glioblastoma, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Kidney Neoplasms, Laryngeal Neoplasms, Leukemia, Liver Neoplasms, Lung Neoplasms, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Melanoma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Central Nervous System Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma, Neuroendocrine Tumors, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Primary Myelofibrosis

NCT03551951 2025-10-08

Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow

320 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Liver Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT04780256 2025-10-03

Endoscopic Resection of Gastrointestinal Neoplasms

2,000 enrolled

Colonic Neoplasms, Duodenal Neoplasms, Esophageal Neoplasms, Stomach Neoplasms

NCT06803147 2025-10-03

BLISS

3,156 enrolled

Barrett Esophagus, Esophageal Neoplasms

NCT00900419 2025-09-22

Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal Volunteers

GastrointestinalHead & NeckOther neoplasmThoracic

700 enrolled

Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Lung Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Precancerous Conditions, Salivary Gland Neoplasms, Tongue Neoplasms, Small Cell Lung Carcinoma

NCT04892849 2025-09-17

ST-ICI02

GastrointestinalGenitourinaryHead & Neck

200 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Esophageal Neoplasms

NCT07165184 2025-09-10

Incidence of 107 Lymph Node Metastasis

1,100 enrolled

Esophageal Neoplasms, Lymphatic Metastasis

NCT07165210 2025-09-10

Incidence of 106TBL Lymph Node Metastasis

1,852 enrolled

Esophageal Neoplasms, Lymphatic Metastasis

NCT05059444 2025-08-22

ORACLE

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

2,020 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Esophageal Neoplasms, Fallopian Tube Neoplasms, Melanoma, Rectal Neoplasms, Ureteral Neoplasms, Endometrial Neoplasms

NCT06597240 2025-08-14

AMCOR

30 enrolled

Esophageal Neoplasms

NCT06605404 2025-08-14

Pan-tumor MRD Study

DermatologicGastrointestinalThoracic

1,350 enrolled

Adenocarcinoma, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Melanoma

NCT07114627 2025-08-11

ESCAPE

66 enrolled

Esophageal Neoplasms, Neoplasms, Colorectal Neoplasms, Hand-Foot Syndrome

NCT00288119 2025-07-18

FBE

2,000 enrolled