Announcements Trials
Browse Landscape

Phase

Phase 2 3Phase NA 1Phase 1/2 1

Status

Recruiting 2Not yet recruiting 1Completed 1Active not recruiting 1

Sponsor Class

OTHER 5

Study Type

Interventional 5

Sponsor

Cancer Type

Gastrointestinal 5

Conditions

Breast Neoplasms 19Esophageal Squamous Cell Carcinoma 5Neoplasms 4Carcinoma, Non-Small-Cell Lung 4Rectal Neoplasms 3Head and Neck Neoplasms 3Carcinoma, Hepatocellular 3Urinary Bladder Neoplasms 2Triple Negative Breast Neoplasms 2Stomach Neoplasms 2Squamous Cell Carcinoma of Head and Neck 2Sarcoma 2Ovarian Neoplasms 2Neoplasm, Residual 2Neoplasm Metastasis 2Lymphoma, Large B-Cell, Diffuse 2Lung Neoplasms 2Esophageal Neoplasms 2Colorectal Neoplasms 2Colonic Neoplasms 2Waldenstrom Macroglobulinemia 1Turcot syndrome 1Testicular Neoplasms 1Surgery 1Stress, Psychological 1Squamous Cell Carcinoma of External Auditory Canal 1Solitary Fibrous Tumor, Pleural 1Seminoma 1Recurrence 1Postoperative Complications 1

Interventions

Cisplatin 26Paclitaxel 21pembrolizumab 15Radiotherapy 13Carboplatin 13tislelizumab 12Fluorouracil 12Drug Therapy 11Irinotecan 9toripalimab 8Esophagectomy 8Oxaliplatin 6Nivolumab 6Capecitabine 6Neoadjuvant Therapy 5Leucovorin 5Docetaxel 5lenvatinib 4camrelizumab 4Taxes 4Radiation 4Levoleucovorin 4Immune Checkpoint Inhibitors 4Albumin-Bound Paclitaxel 4130-nm albumin-bound paclitaxel 4spartalizumab 3sintilimab 3apatinib 3Itraconazole 3Injections 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Esophageal Squamous Cell Carcinoma × Neoadjuvant Therapy × 1 year × Clear all
NCT07244978 2026-04-24

Neoadjuvant Ivonescimab(AK112) Combined With Chemotherapy in Patients With Resectable Esophageal Squamous Cell Carcinoma

Second Affiliated Hospital, School of Medicine, Zhejiang University

Phase 2 Not yet recruiting
49 enrolled
Gastrointestinal

Esophageal Squamous Cell Carcinoma

NCT07385001 2026-02-03

A Prospective, Multicenter, Phase Ib/II Trial of Ivonescimab (AK112) Combined With Albumin-Paclitaxel and Cisplatin as Neoadjuvant Therapy for ESCC

Tang-Du Hospital

Phase 1/2 Recruiting
45 enrolled
Gastrointestinal

Esophageal Squamous Cell Carcinoma

NCT05659251 2025-12-02

Serplulimab Combined With Chemotherapy in Patients With Resectable Esophageal Squamous Cell Carcinoma

Second Affiliated Hospital, School of Medicine, Zhejiang University

Phase 2 Active not recruiting
48 enrolled
Gastrointestinal

Esophageal Squamous Cell Carcinoma

NCT07236320 2025-11-19

Neoadjuvant Immunochemotherapy vs Chemoradiotherapy in ESCC

Sichuan Cancer Hospital and Research Institute

Phase NA Completed
200 enrolled
Gastrointestinal

Esophageal Squamous Cell Carcinoma

NCT06601309 2025-09-15

ESCC

Fujian Medical University Union Hospital

Phase 2 Recruiting
90 enrolled
Gastrointestinal

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

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