Announcements Trials
Browse Landscape

Phase

Phase 2 5

Status

Unknown 4Completed 1

Sponsor Class

OTHER 5

Study Type

Interventional 5

Sponsor

Cancer Type

Gastrointestinal 5

Conditions

Carcinoma, Non-Small-Cell Lung 25Squamous Cell Carcinoma of Head and Neck 10Lung Neoplasms 10Neoplasms 6Neoplasm Metastasis 6Head and Neck Neoplasms 6Esophageal Squamous Cell Carcinoma 5Breast Neoplasms 5Pancreatic Neoplasms 4Carcinoma, Squamous Cell 4Stomach Neoplasms 3Esophageal Neoplasms 3Brain Neoplasms 3Prostatic Neoplasms 2Non-small-cell Lung Cancer With Somatic EGFR Mutations 2NSCLC 2Glioblastoma 2Colorectal Neoplasms 2Adenocarcinoma of Lung 2Urinary Bladder Neoplasms 1Urethral Neoplasms 1Ureteral Neoplasms 1Unilateral HER2 Positive Breast Cancer 1Triple Negative Breast Neoplasms 1Thrombocytosis 1Thoracic Neoplasms 1Squamous Cell Cancers of the Head and Neck 1Solid Tumors 1Small Cell Lung Carcinoma 1Skin Neoplasms 1

Interventions

Cisplatin 86Radiotherapy 71Paclitaxel 50Fluorouracil 38Carboplatin 36Drug Therapy 32Neoadjuvant Therapy 23toripalimab 19tislelizumab 18pembrolizumab 17camrelizumab 17Irinotecan 17Esophagectomy 17Surgical Procedures, Operative 16Radiation 16Docetaxel 16sintilimab 15Oxaliplatin 14130-nm albumin-bound paclitaxel 14nimotuzumab 11TP protocol 11S 1 (combination) 11Radiotherapy, Intensity-Modulated 11Cetuximab 11Capecitabine 11Albumin-Bound Paclitaxel 10apatinib 9Leucovorin 9Immune Checkpoint Inhibitors 8nedaplatin 7

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
OTHER × Esophageal Squamous Cell Carcinoma × Afatinib × Clear all
NCT04839471 2024-07-08

BEAR

National Health Research Institutes, Taiwan

Phase 2 Completed
49 enrolled
Gastrointestinal

Esophageal Squamous Cell Carcinoma

NCT05865132 2023-05-18

Palbociclib Combined With Afatinib for Advanced Squamous Carcinoma of Esophagus or Gastroesophageal Junction

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Phase 2 Unknown
30 enrolled
Gastrointestinal

Esophageal Squamous Cell Carcinoma

NCT04880811 2021-07-13

Afatinib Plus Toripalimab in Previously Treated ESCC With EGFR Overexpression or EGFR Amplification

Peking University

Phase 2 Unknown
43 enrolled
Gastrointestinal

Esophageal Squamous Cell Carcinoma

NCT03940976 2019-06-11

Afatinib in Previously Treated ESCC With EGFR Overexpression or EGFR Amplification (ESCC-A01)

Peking University

Phase 2 Unknown
40 enrolled
Gastrointestinal

Esophageal Squamous Cell Carcinoma

NCT02353936 2019-02-11

A Phase II Trial of Afatinib in Patients With Metastatic or Recurrent Squamous Cell Carcinoma of Esophagus

Yonsei University

Phase 2 Unknown
30 enrolled
Gastrointestinal

Esophageal Squamous Cell Carcinoma

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