Clinical Trials

37 enrolled

GastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Esophageal Squamous Cell Carcinoma

NCT04389632 2026-05-11

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

Phase 1 Recruiting

1,006 enrolled

Adenocarcinoma Of Esophagus, Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Ovarian Neoplasms, Stomach Neoplasms

NCT07559045 2026-04-30

Induction Chemo-Immunotherapy + Radiotherapy vs Concurrent Chemoradiotherapy for Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma

92 enrolled

CNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Esophageal Squamous Cell Carcinoma

NCT06047379 2026-03-02

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

Phase 1/2 Recruiting

134 enrolled

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Astrocytoma, Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Glioblastoma, Melanoma, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Central Nervous System Neoplasms, Small Cell Lung Carcinoma

NCT07403435 2026-02-11

Short-course Radiotherapy Combined With Serplulimab and Chemotherapy as Neoadjuvant Treatment for Resectable ESCC

Phase 2 Not yet recruiting

22 enrolled

Esophageal Squamous Cell Carcinoma

NCT07317609 2026-01-05

Endosurgery-02

Phase 1 Recruiting

60 enrolled

Esophageal Squamous Cell Carcinoma

NCT07266493 2025-12-05

Efficacy and Safety of Neoadjuvant Envafolimab Combined With Albumin-bound Paclitaxel and Carboplatin for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma

26 enrolled

Esophageal Squamous Cell Carcinoma

NCT06576973 2025-12-02

Adbelimumab Combined With Chemotherapy and Apatinib in Patients With Resectable Esophageal Squamous Cell Carcinoma

35 enrolled

Phase 2 Active not recruiting

Esophageal Squamous Cell Carcinoma

NCT05189730 2025-11-20

ETNT

80 enrolled

Phase 2 Active not recruiting

Esophageal Squamous Cell Carcinoma

NCT04929392 2025-09-04

Chemoradiation and Pembrolizumab Followed by Pembrolizumab and Lenvatinib Before Surgery for the Treatment of Non-metastatic Esophageal or Esophageal/Gastroesophageal Junction Cancer

3 enrolled

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma

NCT05880082 2025-08-24

PPIO-004-EC001

118 enrolled

Phase 3 Enrolling by invitation

Esophageal Squamous Cell Carcinoma

NCT07016737 2025-06-12

ESO-Nanjing12

79 enrolled

Phase 2 Not yet recruiting

Esophageal Squamous Cell Carcinoma

NCT06861894 2025-05-15

Active Surveillance After Neoadjuvant Adebrelimab Combined With Chemoradiotherapy for Resectable ESCC

164 enrolled

Esophageal Squamous Cell Carcinoma

NCT06637163 2025-04-17

Benmelstobart Combined With Radiochemotherapy as Neoadjuvant Treatment Iin ESCC

100 enrolled

Esophageal Squamous Cell Carcinoma

NCT02735239 2024-03-22

Study of Anti-PD-L1 in Combination With Chemo(Radio)Therapy for Oesophageal Cancer

Phase 1/2 Completed

73 enrolled 18 charts

Phase 1/2 Enrolling by invitation

Adenocarcinoma Of Esophagus, Diabetes Mellitus, Insulin-Dependent, 12, Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT06303583 2024-03-12

CRIS

30 enrolled

Esophageal Squamous Cell Carcinoma

NCT04568200 2024-01-22

Study of Anti-PD-L1 in Combination With Chemo(Radio)Therapy for Resectable Esophageal Squamous Cell Carcinoma

60 enrolled

Esophageal Squamous Cell Carcinoma

NCT02916511 2023-12-22

ESO-Shanghai9

70 enrolled

Esophageal Squamous Cell Carcinoma

NCT06122493 2023-11-08

Optimization of Treatment Strategy for Unresectable cN3 Esophageal Squamous Cell Carcinoma

48 enrolled

Esophageal Squamous Cell Carcinoma

NCT05302011 2023-10-10

Neoadjuvant Pembrolizumab Plus Chemotherapy for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma

28 enrolled

Esophageal Squamous Cell Carcinoma

NCT06056336 2023-09-28

Perioperative Tislelizumab Plus Chemotherapy for Resectable Thoracic Oesophageal Squamous Cell Carcinoma

73 enrolled

Phase 2 Active not recruiting

Esophageal Squamous Cell Carcinoma

NCT04764227 2023-08-03

Phase II Study of Postoperative Concurrent Chemoradiotherapy for Esophageal Squamous Cell Carcinoma (ESO- Shanghai 17)

70 enrolled

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT00003864 2023-06-15

Docetaxel Plus Carboplatin in Treating Patients With Advanced Cancer of the Esophagus

Phase 2 Not yet recruiting

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT05896787 2023-06-09

Candonilimab (AK104) Plus Preoperative Chemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma (ESCC)

45 enrolled

Esophageal Squamous Cell Carcinoma

NCT05650216 2022-12-14

Camrelizumab Combined With Neoadjuvant Concurrent Chemoradiotherapy for Resectable Locally Advanced ESCC（NICE-RT）

50 enrolled

Esophageal Squamous Cell Carcinoma

NCT05596890 2022-11-28

PICCRT

50 enrolled

Esophageal Squamous Cell Carcinoma, Deglutition Disorders

NCT05552651 2022-09-23

Envafolimab Combined With Chemotherapy in Neoadjuvant Therapy for Resectable Esophageal Squamous Cell Carcinoma

40 enrolled

Esophageal Squamous Cell Carcinoma

NCT05394415 2022-05-27

LATE

Phase 1/2 Unknown

30 enrolled

Esophageal Squamous Cell Carcinoma

NCT03278626 2022-03-28

Immune Checkpoint Therapy With Nivolumab Esophageal Squamous Cell Carcinoma

Phase 1/2 Terminated

12 enrolled 8 charts

Esophageal Squamous Cell Carcinoma

NCT02459457 2022-02-09

A Comparison of Paclitaxel-based Three Regimens Concurrent With Radiotherapy for Patients With Local Advanced Esophageal Cancer

Phase 3 Completed

321 enrolled

Esophageal Squamous Cell Carcinoma

NCT04506138 2021-12-14

Camrelizumab in Combination With Neoadjuvant Chemotherapy for Resectable Thoracic Esophageal Squamous Cell Carcinoma

Phase 1/2 Unknown

46 enrolled

Esophageal Squamous Cell Carcinoma

NCT04519905 2021-11-02

Phase III Study of Concurrent Radiotherapy in Elderly Patients With Esophageal Squamous Cell Carcinoma (ESO-Shanghai 15)

Phase NA Recruiting

320 enrolled

Esophageal Squamous Cell Carcinoma

NCT05044728 2021-09-16

Exploration of Immunodynamic Monitoring in the Population Evaluation of Neoadjuvant Chemotherapy Immunotherapy in Patients With Solid Tumors of the Chest.

80 enrolled

GastrointestinalThoracic

Esophageal Squamous Cell Carcinoma, Carcinoma, Non-Small-Cell Lung

NCT04767295 2021-02-23

A Study of Camrelizumab Combined With Chemotherapy as Neoadjuvant Therapy in Adcanced Esophageal Squamous Cell Carcinoma (ESCC)

28 enrolled

Esophageal Squamous Cell Carcinoma

NCT04644250 2020-11-25

Combination of Toripalimab and Neoadjuvant Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma

32 enrolled

BreastGastrointestinalGynecologicHead & NeckThoracic

Esophageal Squamous Cell Carcinoma

NCT02658214 2020-08-20

Durvalumab and Tremelimumab in Combination With First-Line Chemotherapy in Advanced Solid Tumors

Phase 1 Completed

32 enrolled

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Fallopian Tube Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Peritoneal Neoplasms, Stomach Neoplasms, Carcinoma, Pancreatic Ductal, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT00006472 2020-08-18

Combination Chemotherapy Plus Radiation Therapy Followed By Surgery in Treating Patients With Stage I, Stage II, or Stage III Esophageal Cancer

Phase 2 Terminated

4 enrolled

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT00022139 2016-12-07

Radiation Therapy and Paclitaxel, Carboplatin, and Fluorouracil Followed by Esophagectomy in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction

56 enrolled

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms, Stomach Neoplasms

NCT00268437 2016-07-06

Radiation Therapy, Pemetrexed Disodium, and Carboplatin in Treating Patients With Locally Advanced Esophageal Cancer That Can Be Removed By Surgery

Phase 2 Terminated

27 enrolled 6 charts

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT00066716 2009-12-08

Celecoxib, Paclitaxel, and Carboplatin in Treating Patients With Cancer of the Esophagus

39 enrolled