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Phase

Phase 2 9Phase 3 4Phase 1 2Phase NA 1Phase EARLY_PHASE1 1Phase 2/3 1Phase 1/2 1

Status

Completed 1Active not recruiting 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Gastrointestinal 2CNS 1

Conditions

Glioblastoma 28Lung Neoplasms 13Gliosarcoma 13Carcinoma, Non-Small-Cell Lung 13Rectal Neoplasms 12Brain Neoplasms 11Squamous Cell Carcinoma of Head and Neck 10Sarcoma 9Prostatic Neoplasms 9Breast Neoplasms 9Astrocytoma 9Uterine Cervical Neoplasms 8Melanoma 8Glioma 8Esophageal Neoplasms 8Pancreatic Neoplasms 7Head and Neck Neoplasms 7Neoplasm Metastasis 5Lymphoma, Follicular 5Oropharyngeal Neoplasms 4Lymphoma, Mantle-Cell 4Leukemia, Lymphocytic, Chronic, B-Cell 4Carcinoma, Squamous Cell 4Stomach Neoplasms 3Ovarian Neoplasms 3Multiple Myeloma 3Mouth Neoplasms 3Lymphoma, Large B-Cell, Diffuse 3Lymphoma, B-Cell, Marginal Zone 3Lymphoma, B-Cell 3

Interventions

Cisplatin 9pembrolizumab 7Irinotecan 7Radiotherapy 6Fluorouracil 6Docetaxel 5spartalizumab 4Oxaliplatin 4130-nm albumin-bound paclitaxel 4Nivolumab 3Carboplatin 3toripalimab 2tislelizumab 2elgemtumab 2durvalumab 2Radiation 2Paclitaxel 2Leucovorin 2Gemcitabine 2Drug Therapy 2vandetanib 1tremelimumab 1ribociclib 1palbociclib 1obinutuzumab 1nedaplatin 1nazartinib 1naptumomab estafenatox 1liposomal doxorubicin 1dalpiciclib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1 × Esophageal Squamous Cell Carcinoma × Radiation × Clear all
NCT04460937 2026-04-29

Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers

National Cancer Institute (NCI)

Phase 1 Active not recruiting
4 enrolled 9 charts
CNSGastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Brain Neoplasms, Meningeal Carcinomatosis

NCT01561014 2018-07-02

Oxaliplatin, Fluorouracil, Erlotinib Hydrochloride, and Radiation Therapy Before Surgery and Erlotinib Hydrochloride After Surgery in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction

Wake Forest University Health Sciences

Phase 1 Completed
9 enrolled
Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms, Stomach Neoplasms

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