Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Completed 2

Sponsor Class

NIH 2NETWORK 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Sarcoma 1

Conditions

Colorectal Neoplasms 14Rectal Neoplasms 13Colonic Neoplasms 10Esophageal Neoplasms 5Stomach Neoplasms 4Rhabdomyosarcoma 4Pancreatic Neoplasms 4Neuroblastoma 4Central Nervous System Neoplasms 4Adenocarcinoma Of Esophagus 4Sarcoma 3Neoplasm Metastasis 3Medulloblastoma 3Lung Neoplasms 3Wilms Tumor 2Unspecified Childhood Solid Tumor, Protocol Specific 2Sarcoma, Ewing 2Ovarian Neoplasms 2Optic Nerve Glioma 2Oligodendroglioma 2Malignant mesenchymal tumor 2Fibrolamellar hepatocellular carcinoma 2Familial ependymoma 2Esophageal Squamous Cell Carcinoma 2Choroid Plexus Neoplasms 2Astrocytoma 2Uterine Cervical Neoplasms 1Urinary Bladder Neoplasms 1Urethral Neoplasms 1Stage I Mixed Cell Type Kidney Wilms Tumor 1

Interventions

Psychiatric Rehabilitation 2Irinotecan 2transforming growth factor(alpha)-Pseudomonas aeruginosa exotoxin (38) 1ribociclib 1lonafarnib 1laromustine 1emvododstat 1Vinorelbine 1Vincristine 1Valproic Acid 1Topotecan 1Temozolomide 1Semaxinib 1Oxaliplatin 1N(alpha)-(4-amino-4-deoxypteroyl)-N(delta)-hemiphthaloyl-L-ornithine 1Everolimus 1Drug Therapy 1Busulfan 13-(4-((4-chlorophenyl)sulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)propanoic acid 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
NETWORK × Familial ependymoma × Irinotecan × Clear all
NCT00138216 2023-10-02

Temozolomide, Vincristine, and Irinotecan in Treating Young Patients With Refractory Solid Tumors

Children's Oncology Group

Phase 1 Completed
42 enrolled
CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

NCT00004078 2013-06-14

Irinotecan in Treating Children With Refractory Solid Tumors

Children's Oncology Group

Phase 2 Completed
181 enrolled
CNSSarcoma

Familial ependymoma, Astrocytoma, Medulloblastoma, Neuroblastoma, Oligodendroglioma, Osteosarcoma, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

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