Announcements Trials
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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Gynecologic 1Gastrointestinal 1

Conditions

Colorectal Neoplasms 3Uveal Melanoma 2Ovarian Neoplasms 2Neoplasm Metastasis 2Melanoma 2Carcinoma, Renal Cell 2Uterine Cervical Neoplasms 1Stomach Neoplasms 1Squamous Cell Carcinoma of Head and Neck 1Small Cell Lung Carcinoma 1Sarcoma 1Lung Neoplasms 1Glioblastoma 1Fibrolamellar hepatocellular carcinoma 1Esophageal Squamous Cell Carcinoma 1Esophageal Neoplasms 1Central Nervous System Neoplasms 1Carcinoma, Transitional Cell 1Carcinoma, Squamous Cell 1Carcinoma, Non-Small-Cell Lung 1Carcinoma, Merkel Cell 1Carcinoma 1Brain Neoplasms 1Astrocytoma 1Adenoma, Islet Cell 1

Interventions

Nivolumab 3Ipilimumab 3poly ICLC 2Specimen Handling 2Sorafenib 2Irinotecan 2spartalizumab 1sapanisertib 1pembrolizumab 1durvalumab 1dostarlimab 1dehydroftorafur 1balstilimab 1atezolizumab 1aflibercept 1Watchful Waiting 1Vincristine 1Surveys and Questionnaires 1Platinum 1Oxaliplatin 1Observation 1Gemcitabine 1Fluorouracil 1Etoposide 1Doxorubicin 1DT2216 1Cyclophosphamide 1Cisplatin 1Carboplatin 1Bevacizumab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Fibrolamellar hepatocellular carcinoma × aflibercept × 1 year × Clear all
NCT02159989 2025-10-20

Sapanisertib and Ziv-Aflibercept in Treating Patients With Recurrent Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

National Cancer Institute (NCI)

Phase 1 Completed
83 enrolled 21 charts
GastrointestinalGynecologic

Fibrolamellar hepatocellular carcinoma, Adenoma, Islet Cell, Neoplasm Metastasis, Ovarian Neoplasms

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