Announcements Trials
Browse Landscape

Phase

Phase 1 3Phase 1/2 1

Status

Recruiting 3Suspended 1

Sponsor Class

OTHER 2INDUSTRY 2

Study Type

Interventional 4

Sponsor

Cancer Type

Other hematologic neoplasm 4Myeloid 1Classical hematology 1

Conditions

Leukemia, Myeloid, Acute 188Leukemia, Lymphocytic, Chronic, B-Cell 69Myelodysplastic Syndromes 47Recurrence 30Leukemia 30Precursor Cell Lymphoblastic Leukemia-Lymphoma 24Lymphoma, Mantle-Cell 20Leukemia, Myelomonocytic, Chronic 19Hematologic Neoplasms 14Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 13Lymphoma, Non-Hodgkin 13Lymphoma 13Leukemia, Biphenotypic, Acute 13Burkitt Lymphoma 13Lymphoma, B-Cell, Marginal Zone 12Multiple Myeloma 11Lymphoma, Large B-Cell, Diffuse 11Neoplasms 10Waldenstrom Macroglobulinemia 8Myeloproliferative Disorders 8Lymphoma, Follicular 8Lymphoma, B-Cell 7Neoplasm, Residual 6Leukemia, Myeloid 5Blastic Plasmacytoid Dendritic Cell Neoplasm 5Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 4Leukemia, Myelogenous, Chronic, BCR-ABL Positive 4GATA2 Deficiency 4Leukemia, Monocytic, Acute 3Immunoglobulin Light-chain Amyloidosis 3

Interventions

venetoclax 4Azacitidine 4Specimen Handling 3regorafenib 1iadademstat 1fludarabine phosphate 1fludarabine 1decitabine and cedazuridine drug combination 1Whole-Body Irradiation 1Vorinostat 1Thiotepa 1Tacrolimus 1Methotrexate 1Lenalidomide 1Cyclophosphamide 1Busulfan 1Bone Marrow Transplantation 1Biopsy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
GATA2 Deficiency × venetoclax × 1 year × Clear all
NCT06372717 2026-06-01

A Study to Investigate APL-4098 Alone and in Combination in Adults With AML or MDS

Apollo Therapeutics Ltd

Phase 1 Recruiting
100 enrolled
Classical hematologyOther hematologic neoplasm

GATA2 Deficiency, Anemia, Refractory, with Excess of Blasts, Leukemia, Myeloid, Acute

NCT06454409 2025-11-19

Regorafenib in Combination With Venetoclax and Azacitidine for the Treatment of Patients With Relapsed or Refractory Acute Myeloid Leukemia

City of Hope Medical Center

Phase 1 Suspended
20 enrolled
MyeloidOther hematologic neoplasm

GATA2 Deficiency, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT05211570 2025-10-02

AB8939 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

AB Science

Phase 1/2 Recruiting
78 enrolled
Other hematologic neoplasm

GATA2 Deficiency, Leukemia, Myeloid, Acute

NCT06357182 2025-08-12

Iadademstat in Combination With Azacitidine and Venetoclax in Treating Newly Diagnosed Acute Myeloid Leukemia

OHSU Knight Cancer Institute

Phase 1 Recruiting
24 enrolled
Other hematologic neoplasm

GATA2 Deficiency, Leukemia, Myeloid, Acute

Data powered by HemOnc (CC BY 4.0) Colophon âš¡