Announcements Trials
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Phase

Phase 1 3Phase 1/2 1

Status

Recruiting 2Suspended 1

Sponsor Class

OTHER 2INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

Other hematologic neoplasm 3Myeloid 1Classical hematology 1

Conditions

Leukemia, Myeloid, Acute 95Myelodysplastic Syndromes 26Recurrence 25Lymphoma, Non-Hodgkin 24Neoplasms 21Leukemia, Lymphocytic, Chronic, B-Cell 19Lymphoma, Large B-Cell, Diffuse 15Leukemia 12Lymphoma, Follicular 10Multiple Myeloma 9Hematologic Neoplasms 9Lymphoma, B-Cell, Marginal Zone 8Burkitt Lymphoma 7Lymphoma, Mantle-Cell 6Lymphoma, B-Cell 6Lymphoma 6Leukemia, Myelomonocytic, Chronic 6Leukemia, Myeloid 6Precursor Cell Lymphoblastic Leukemia-Lymphoma 5Neoplasm Metastasis 4Myeloproliferative Disorders 4Leukemia, Biphenotypic, Acute 4Small Cell Lung Carcinoma 3Prostatic Neoplasms 3GATA2 Deficiency 3Carcinoma, Non-Small-Cell Lung 3Breast Neoplasms 3Primary Myelofibrosis 2Immunoglobulin Light-chain Amyloidosis 2Colorectal Neoplasms 2

Interventions

venetoclax 3Specimen Handling 3Azacitidine 3regorafenib 1iadademstat 1decitabine and cedazuridine drug combination 1Nivolumab 1Biopsy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 1 × GATA2 Deficiency × venetoclax × Clear all
NCT06372717 2026-06-01

A Study to Investigate APL-4098 Alone and in Combination in Adults With AML or MDS

Apollo Therapeutics Ltd

Phase 1 Recruiting
100 enrolled
Classical hematologyOther hematologic neoplasm

GATA2 Deficiency, Anemia, Refractory, with Excess of Blasts, Leukemia, Myeloid, Acute

NCT06454409 2025-11-19

Regorafenib in Combination With Venetoclax and Azacitidine for the Treatment of Patients With Relapsed or Refractory Acute Myeloid Leukemia

City of Hope Medical Center

Phase 1 Suspended
20 enrolled
MyeloidOther hematologic neoplasm

GATA2 Deficiency, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT06357182 2025-08-12

Iadademstat in Combination With Azacitidine and Venetoclax in Treating Newly Diagnosed Acute Myeloid Leukemia

OHSU Knight Cancer Institute

Phase 1 Recruiting
24 enrolled
Other hematologic neoplasm

GATA2 Deficiency, Leukemia, Myeloid, Acute

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