Announcements Trials
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Phase

Phase 2 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Lymphoma 215Precursor Cell Lymphoblastic Leukemia-Lymphoma 188Lymphoma, Large B-Cell, Diffuse 172Leukemia 102Burkitt Lymphoma 91Lymphoma, Non-Hodgkin 89Lymphoma, Follicular 78Lymphoma, Mantle-Cell 53Neuroblastoma 51Hodgkin Disease 46Central Nervous System Neoplasms 42Sarcoma 37Lymphoma, B-Cell 31Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 30Lymphoma, Large-Cell, Anaplastic 29Recurrence 28Lymphoma, T-Cell, Peripheral 28Lymphoma, Large-Cell, Immunoblastic 27Rhabdomyosarcoma 25Neoplasms 25Multiple Myeloma 24Medulloblastoma 22Lymphoma, B-Cell, Marginal Zone 22Leukemia, Lymphocytic, Chronic, B-Cell 21Leukemia, Biphenotypic, Acute 21Brain Neoplasms 20Sarcoma, Ewing 18Retinoblastoma 18Lymphoma, T-Cell 17HIV Infections 17

Interventions

trametinib 2dabrafenib 2mirdametinib 1gallium Ga 68 dotatate 1Vincristine 1Magnetic Resonance Spectroscopy 1Irinotecan 1Ga(III)-DOTATOC 1Carboplatin 1Bevacizumab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Interventional × Ganglioneuroma × Vincristine × Clear all
NCT02684058 2023-12-13

Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors

Novartis

Phase 2 Completed
151 enrolled 45 charts 1 FDA
CNS

Astrocytoma, Ganglioneuroma, Glioblastoma, Glioma, Oligodendroglioma, Ganglioglioma, Neurocytoma

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