Announcements Trials
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Phase

Phase 4 1Phase 2 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Melanoma 30Neoplasms 11Thyroid Neoplasms 7Thyroid Carcinoma, Anaplastic 6Brain Neoplasms 6Multiple Myeloma 4Glioma 4Colorectal Neoplasms 4Hematologic Neoplasms 3Carcinoma, Non-Small-Cell Lung 3Thyroid Cancer, Papillary 2Skin Neoplasms 2Neoplasm Metastasis 2Lymphoma 2Glioblastoma 2Astrocytoma 2Ameloblastoma 2Adenocarcinoma, Follicular 2Uterine Neoplasms 1Uterine Cervical Neoplasms 1Urinary Bladder Neoplasms 1Thyroid cancer, follicular 1Thyroid cancer, Hurthle cell 1Stomach Neoplasms 1Spinocerebellar Degenerations 1Solid Tumor 1Rectal Neoplasms 1Rare Malignant Neoplasm 1Prostatic Neoplasms 1Pancreatic Neoplasms 1

Interventions

trametinib 1dabrafenib 1Vincristine 1Carboplatin 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 2 × Ganglioneuroma × dabrafenib × Clear all
NCT02684058 2023-12-13

Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors

Novartis

Phase 2 Completed
151 enrolled 45 charts 1 FDA
CNS

Astrocytoma, Ganglioneuroma, Glioblastoma, Glioma, Oligodendroglioma, Ganglioglioma, Neurocytoma

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