Announcements Trials
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Phase

Phase 1/2 2

Status

Terminated 1Completed 1

Sponsor Class

NIH 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Gastrointestinal 2

Conditions

Melanoma 20Neoplasm Metastasis 8Leukemia, Myeloid, Acute 7Skin Neoplasms 6Ovarian Neoplasms 6Lymphoma, Non-Hodgkin 6Colorectal Neoplasms 6Carcinoma, Non-Small-Cell Lung 6Leukemia, Lymphocytic, Chronic, B-Cell 5Uveal Melanoma 4Stomach Neoplasms 4Squamous Cell Carcinoma of Head and Neck 4Neoplasms 4Triple Negative Breast Neoplasms 3Recurrence 3Rectal Neoplasms 3Pancreatic Neoplasms 3Mesothelioma, Malignant 3Lymphoma, Follicular 3Lymphoma 3Lung Neoplasms 3Leukemia 3Esophageal Neoplasms 3Carcinoma, Renal Cell 3Uterine Cervical Neoplasms 2Sarcoma 2Pleural Effusion, Malignant 2Neuroblastoma 2Myelodysplastic Syndromes 2Multiple Myeloma 2

Interventions

Fluorouracil 9Oxaliplatin 7Leucovorin 7Surveys and Questionnaires 6Blood Specimen Collection 6Bevacizumab 6Specimen Handling 5Gemcitabine 5Cetuximab 5Capecitabine 5fludarabine 4aldesleukin 4Standard of Care 4Irinotecan 4Cyclophosphamide 4Remote Patient Monitoring 3Radiosurgery 3Pafolacianine 3Nivolumab 3Endoscopic Mucosal Resection 3Cisplatin 3130-nm albumin-bound paclitaxel 3encorafenib 2Tomography, X-Ray Computed 2Sunitinib 2Referral and Consultation 2Radiotherapy 2Practice Guidelines as Topic 2Pemetrexed 2Magnetic Resonance Spectroscopy 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Gastrointestinal Neoplasms × Interleukin-2 × 1 year × Clear all
NCT03745326 2026-05-19

Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients

National Institutes of Health Clinical Center (CC)

Phase 1/2 Terminated
5 enrolled 14 charts
Gastrointestinal

Colonic Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT04426669 2026-02-23

A Study of Metastatic Gastrointestinal Cancers Treated With Tumor Infiltrating Lymphocytes in Which the Gene Encoding the Intracellular Immune Checkpoint CISH Is Inhibited Using CRISPR Genetic Engineering

Intima Bioscience, Inc.

Phase 1/2 Completed
23 enrolled
Gastrointestinal

Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

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