Clinical Trials

160 enrolled

Gastrointestinal Neoplasms

NCT06760819 2026-05-07

panSOHO

BreastGastrointestinalGenitourinaryGynecologicSarcoma

111 enrolled

Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Gastrointestinal Stromal Tumors

NCT06475352 2026-04-23

FUDOSE

400 enrolled

Gastrointestinal Neoplasms, Neoplasm Metastasis, Neoplasms, Recurrence, Colorectal Neoplasms

NCT06864169 2026-04-23

REJOICE-GI01

160 enrolled

Gastrointestinal Neoplasms

NCT02713269 2026-04-17

Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord

DermatologicGastrointestinalGenitourinaryHead & NeckSarcoma

60 enrolled

Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Melanoma, Neoplasms, Unknown Primary, Sarcoma, Spinal Cord Compression, Thyroid Neoplasms

NCT05789485 2026-04-16

A Study on the Effects of Exercise on Side Effects From Treatment for Gastrointestinal Cancers

216 enrolled

Gastrointestinal Neoplasms, Motor Activity

NCT05318027 2026-04-01

ChatBot and Activity Monitoring in Patients Undergoing Chemoradiotherapy

GastrointestinalHead & NeckThoracic

70 enrolled

Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms

NCT04899908 2026-03-19

Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases

BreastCNSDermatologicGastrointestinalThoracic

134 enrolled

Brain Neoplasms, Breast Neoplasms, Gastrointestinal Neoplasms, Lung Neoplasms, Melanoma, Colorectal Neoplasms

NCT05772546 2026-03-13

ACT-GI

60 enrolled

Jacobs syndrome, Gastrointestinal Neoplasms

NCT06855524 2026-02-24

Fucoidan for Preventing Chemotherapy-Related Fatigue in Patients With Gastrointestinal or Gynecological Cancer

34 enrolled

Gastrointestinal Neoplasms

NCT04005339 2026-01-26

NAPOLI-2: Fluorouracil, Leucovorin, and Nanoliposomal Irinotecan in Biliary Cancer

48 enrolled

Biliary Tract Neoplasms, Gastrointestinal Neoplasms

NCT05641896 2026-01-22

18F-FAPI-74 GI

109 enrolled

Gastrointestinal Neoplasms, Carcinoma, Hepatocellular, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT04505553 2026-01-21

Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer

EndocrineGastrointestinalNET

78 enrolled 14 charts

Gastro-enteropancreatic neuroendocrine tumor, Anus Neoplasms, Appendiceal Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Carcinoma, Hepatocellular, Adenoma, Islet Cell, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT05628857 2026-01-06

A Study of RC108-ADC in Subjects With Advanced Digestive System Malignant Tumor

29 enrolled

Gastrointestinal Neoplasms

NCT05001347 2025-12-16

A Clinical Study of TJ004309 With Atezolizumab (TECENTRIQ®) in Patients With Ovarian Cancer and Selected Solid Tumors

BreastGastrointestinalGynecologicHead & NeckThoracic

25 enrolled 11 charts

Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Ovarian Neoplasms, Triple Negative Breast Neoplasms

NCT03800693 2025-11-06

2 Versus 6 Hour Oxaliplatin Infusions in Patients With Gastrointestinal Cancers

60 enrolled

Gastrointestinal Neoplasms

NCT05221320 2025-09-25

Trial of Ulixertinib in Combination With Hydroxychloroquine in Patients With Advanced Gastrointestinal (GI) Malignancies

Phase 2 Terminated

47 enrolled 18 charts

Gastrointestinal Neoplasms, Neoplasms

NCT07039526 2025-09-24

Single Dose Investigator Initiated Pilot Study to Investigate CYTALUX (Pafolacianine) for Intraoperative Detection of Malignant Tissue in Subjects Undergoing Surgical Resection for Cancer.

50 enrolled

Esophageal Neoplasms, Gastrointestinal Neoplasms

NCT04273061 2025-09-22

CAPTIV-8

BreastDermatologicGastrointestinalHead & NeckSarcomaThoracic

200 enrolled

Breast Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Neoplasms, Unknown Primary, Sarcoma, Skin Neoplasms, Urogenital Neoplasms

NCT05980624 2025-09-19

ONS in Gastrointestinal Cancer Patients Undergoing Chemotherapy

175 enrolled

Gastrointestinal Neoplasms

NCT03929666 2025-09-12

A Safety and Efficacy Study of ZW25 (Zanidatamab) Plus Combination Chemotherapy in HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer

74 enrolled

Biliary Tract Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT04111172 2025-08-22

A Vaccine (Ad5.F35-hGCC-PADRE) for the Treatment of Gastrointestinal Adenocarcinoma

48 enrolled

Phase 2 Not yet recruiting

Gastrointestinal Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT07118566 2025-08-12

Hyperthermia Combined With Immune Checkpoint Inhibitors in the Treatment of Advanced Gastrointestinal Malignancies With Liver Metastases

40 enrolled

Hyperthermia, Gastrointestinal Neoplasms

NCT04268121 2025-07-23

NEONEC

EndocrineGastrointestinal

78 enrolled

Gastrointestinal Neoplasms, Carcinoma, Neuroendocrine

NCT06562348 2025-05-01

ctDNA-RECIST

167 enrolled

Gastrointestinal Neoplasms, Neoplasm Metastasis

NCT06782022 2025-01-17

COMBIGaPP

80 enrolled

Gastrointestinal Neoplasms

NCT04931420 2024-07-31

Study Comparing Standard of Care Chemotherapy With/ Without Sequential Cytoreductive Surgery for Patients With Metastatic Foregut Cancer and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid Levels

Phase 2 Withdrawn

GastrointestinalThoracic

Gastrointestinal Neoplasms, Liver Neoplasms, Lung Neoplasms, Neoplasm Metastasis

NCT02923934 2024-07-24

A Phase II Trial of Ipilimumab and Nivolumab for the Treatment of Rare Cancers

EndocrineGastrointestinalNET

120 enrolled

Gastrointestinal Neoplasms, Neuroendocrine Tumors

NCT04755920 2024-05-09

SGM-CBM

10 enrolled

CNSGastrointestinal

Brain Diseases, Brain Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT06301828 2024-03-08

Endostar Combined With SBRT and Envafolimab in the Treatment of Advanced Gastrointestinal Tumors

16 enrolled

Gastrointestinal Neoplasms

NCT03549494 2024-02-07

Evaluation of Ocoxin®-Viusid® in Advanced Stomach Cancer and Gastric Esophagogastric Junction

GastrointestinalHead & Neck

45 enrolled

Digestive System Diseases, Digestive System Neoplasms, Esophageal Diseases, Esophageal Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Stomach Diseases, Stomach Neoplasms

NCT03559543 2024-02-07

Evaluation of Ocoxin®-Viusid® in Metastatic Colorectal Adenocarcinoma

40 enrolled

EndocrineGastrointestinalNET

Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Rectal Diseases, Colorectal Neoplasms

NCT02859064 2023-12-05

Study of Lanreotide in Patients With Metastatic Gastrointestinal Neuroendocrine Tumors Who Are Undergoing Liver-directed Radioembolization With Yttrium-90 Microspheres

Phase 2 Terminated

6 enrolled 12 charts

Carcinoid Tumor, Gastrointestinal Neoplasms, Neuroendocrine Tumors

NCT05494060 2023-11-07

EXPLORING

80 enrolled

Carcinoma, Digestive System Diseases, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Stomach Neoplasms

NCT00019760 2023-10-31

Isolated Hepatic Perfusion With Melphalan Followed By Chemotherapy in Treating Patients With Unresectable Colorectal Cancer That is Metastatic to the Liver

Colonic Neoplasms, Gastrointestinal Neoplasms, Carcinoma, Hepatocellular, Neoplasm Metastasis, Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Genetic Diseases, Inborn

NCT00020345 2023-10-31

Combination Chemotherapy and Radiation Therapy Plus Surgery in Treating Patients With Advanced Cancer of the Pancreas

Gastrointestinal Neoplasms, Neoplasms, Pancreatic Neoplasms

NCT04591431 2023-10-03

ROME

BreastGastrointestinalThoracic

400 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms

NCT04644315 2023-08-07

ALpha-T

Phase 2 Terminated

1 enrolled 5 charts

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidNETSarcomaThoracic

Thyroid Cancer, Papillary, Brain Neoplasms, Breast Neoplasms, Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Renal Cell, Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Melanoma, Neoplasms, Neoplasms by Site, Ovarian Neoplasms, Pancreatic Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Salivary Gland Neoplasms, Sarcoma, Thoracic Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Lymphoma, Large-Cell, Anaplastic, Cholangiocarcinoma, Neuroendocrine Tumors

NCT05281003 2023-07-13

HYPERION

128 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Squamous Cell Carcinoma, Hypoxia, Digestive System Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Neoplasms

NCT01845337 2023-05-12

TOFFEE

59 enrolled

Bile Duct Neoplasms, Gastrointestinal Neoplasms, Neoplasms, Unknown Primary, Pancreatic Neoplasms

NCT05429866 2023-03-08

Immunological Variables Associated to ICI Toxicity in Cancer Patients

BreastDermatologicGastrointestinalGenitourinaryHead & NeckOther solid neoplasmThoracic

441 enrolled

Mesothelioma, Malignant, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Melanoma, Carcinoma, Merkel Cell, Small Cell Lung Carcinoma

NCT05252078 2022-12-16

ALTER-E005

30 enrolled

Esophageal Squamous Cell Carcinoma, Carcinoma, Squamous Cell, Digestive System Diseases, Digestive System Neoplasms, Esophageal Diseases, Esophageal Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Squamous Cell

NCT05651672 2022-12-15

Pemigatinib in the Advanced Gastrointestinal Cancer With FGFR 1-3 Alterations

100 enrolled

Gastrointestinal Neoplasms

NCT05559775 2022-09-29

A Single-Arm Phase II Exploratory Clinical Study of Pemigatinib in the Treatment of Advanced Gastrointestinal Cancer (Excluding Biliary Tract Cancer) Patients With FGFR Alterations Who Have Failed Standard Therapy

20 enrolled

Gastrointestinal Neoplasms

NCT04080843 2022-07-13

ALTER-C-002

30 enrolled

Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms

NCT03329690 2022-03-18

DS-8201a in Human Epidermal Growth Factor Receptor 2 (HER2)-Expressing Gastric Cancer [DESTINY-Gastric01]

233 enrolled 26 charts 1 FDA

Adenocarcinoma, Gastrointestinal Neoplasms

NCT05225844 2022-02-07

An Exploratory Trail of Camrelizumab Plus Apatinib Mesylate for Advanced Gastrointestinal

150 enrolled

Gastrointestinal Neoplasms

NCT02595320 2021-12-20

X7-7

200 enrolled

BreastGastrointestinal

Breast Neoplasms, Gastrointestinal Neoplasms, Neoplasm Metastasis, Neoplasms

NCT02092298 2021-06-15

Laparoscopic Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) for Metastatic Gastric Cancer

21 enrolled 7 charts