Announcements Trials
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Phase

Phase 2 3Phase 4 2Phase 3 2

Status

Completed 2Terminated 1

Sponsor Class

INDUSTRY 2NETWORK 1

Study Type

Interventional 3

Sponsor

Conditions

Breast Neoplasms 9Multiple Myeloma 5Neoplasms 4Neoplasm Metastasis 4Kidney Neoplasms 3Giant Cell Tumor of Bone 3Smoldering Multiple Myeloma 2Prostatic Neoplasms 2Lung Neoplasms 2Carcinoma, Renal Cell 2Carcinoma, Non-Small-Cell Lung 2Urinary Bladder Neoplasms 1Ureteral Neoplasms 1Thyroid Neoplasms 1Thyroid Cancer Metastatic 1Recurrence 1Parathyroid Neoplasms 1Pancreatic Neoplasms 1Osteosarcoma 1Osteoblastoma 1Neoplastic Cells, Circulating 1Melanoma 1Lymphoma, Non-Hodgkin 1Lymphoma 1Inflammatory Breast Neoplasms 1Hypercalcemia 1Humoral Hypercalcemia Of Malignancy 1Hodgkin Disease 1Head and Neck Neoplasms 1Granuloma, Giant Cell 1

Interventions

Denosumab 3gentamicin-polymethylmethacrylate bead 1fludarabine 1aldesleukin 1Zoledronic Acid 1Vitamin D 1Nivolumab 1Ipilimumab 1Dasatinib 1Cyclophosphamide 1Calcium 1CTLA-4 Antigen 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 2 × Giant Cell Tumor of Bone × Denosumab × Clear all
NCT00396279 2022-11-08

Safety and Efficacy Study of Denosumab in Patients With Recurrent or Unresectable Giant Cell Tumor of Bone

Amgen

Phase 2 Completed
37 enrolled 13 charts

Giant Cell Tumor of Bone

NCT00680992 2022-09-22

Study of Denosumab in Subjects With Giant Cell Tumor of Bone

Amgen

Phase 2 Completed
535 enrolled 16 charts

Giant Cell Tumors, Neoplasms, Giant Cell Tumor of Bone

NCT03620149 2021-01-06

REDUCE

European Organisation for Research and Treatment of Cancer - EORTC

Phase 2 Terminated
2 enrolled

Giant Cell Tumor of Bone

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