Announcements Trials
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Phase

Phase 4 2Phase 2 2Phase 3 1

Status

Completed 4Not yet recruiting 1Active not recruiting 1

Sponsor Class

INDUSTRY 6OTHER 3NETWORK 1

Study Type

Interventional 5Observational 1

Sponsor

Conditions

Neoplasms 8Breast Neoplasms 8Multiple Myeloma 6Giant Cell Tumor of Bone 6Prostatic Neoplasms 5Fractures, Bone 4Neoplasm Metastasis 3Bone Diseases, Metabolic 3Spinal Cord Compression 2Osteoporosis 2Lymphoma 2Carcinoma, Non-Small-Cell Lung 2Bone Neoplasms 2Bone Metastases 2Bone Diseases 2Thyroid Neoplasms 1Recurrence 1Parathyroid Neoplasms 1Paraproteinemias 1Pancreatic Neoplasms 1Neoplastic Processes 1Neoplasms, Plasma Cell 1Multiple Endocrine Neoplasia Type 1 1Lymphoma, Non-Hodgkin 1Lung Neoplasms 1Kidney Neoplasms 1Hypercalcemia 1Humoral Hypercalcemia Of Malignancy 1Hormone Refractory Prostate Cancer 1Hodgkin Disease 1

Interventions

Denosumab 6Vitamin D 2Calcium 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
INDUSTRY × Giant Cell Tumor of Bone × Denosumab × Clear all
NCT04586660 2025-10-01

Study of XGEVA® (Denosumab) in Chinese Adults and Skeletally Mature Adolescents With Giant Cell Tumor of the Bone

Amgen

Phase 4 Active not recruiting
36 enrolled

Giant Cell Tumor of Bone

NCT03301857 2024-05-20

Long-term Safety Follow-up of Subjects With Giant Cell Tumor of Bone Treated With Denosumab in Study 20062004

Amgen

Phase 4 Completed
85 enrolled 13 charts

Giant Cell Tumor of Bone

NCT05813665 2023-04-19

A Study to Evaluate the Efficacy and Safety of Narlumosbart (JMT103) in Patients With Giant Cell Tumor of Bone

Shanghai JMT-Bio Inc.

Phase 3 Not yet recruiting
146 enrolled

Giant Cell Tumor of Bone

NCT00396279 2022-11-08

Safety and Efficacy Study of Denosumab in Patients With Recurrent or Unresectable Giant Cell Tumor of Bone

Amgen

Phase 2 Completed
37 enrolled 13 charts

Giant Cell Tumor of Bone

NCT00680992 2022-09-22

Study of Denosumab in Subjects With Giant Cell Tumor of Bone

Amgen

Phase 2 Completed
535 enrolled 16 charts

Giant Cell Tumors, Neoplasms, Giant Cell Tumor of Bone

NCT05402865 2022-06-02

A Real-world Study on Patients of Unresectable Giant Cell Tumor of Bone

Shanghai JMT-Bio Inc.

Completed
301 enrolled

Giant Cell Tumor of Bone

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