Announcements Trials
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Phase

Phase 2 3Phase 4 2Phase 3 2

Status

Completed 3Unknown 1Terminated 1Not yet recruiting 1Active not recruiting 1

Sponsor Class

INDUSTRY 5OTHER 1NETWORK 1

Study Type

Interventional 7Observational 3

Sponsor

Conditions

Breast Neoplasms 25Neoplasms 12Prostatic Neoplasms 9Multiple Myeloma 9Neoplasm Metastasis 7Giant Cell Tumor of Bone 7Osteoporosis 4Fractures, Bone 4Recurrence 3Kidney Neoplasms 3Carcinoma, Renal Cell 3Carcinoma, Non-Small-Cell Lung 3Bone Diseases, Metabolic 3Bone Diseases 3Spinal Cord Compression 2Smoldering Multiple Myeloma 2Parathyroid Neoplasms 2Melanoma 2Lymphoma 2Lung Neoplasms 2Bone Neoplasms 2Bone Metastases 2Bone Cysts, Aneurysmal 2With MSS/pMMR Advanced, Platinum-resistant Ovarian Cancer 1Urinary Bladder Neoplasms 1Ureteral Neoplasms 1Thyroid Neoplasms 1Thyroid Cancer Metastatic 1Paraproteinemias 1Pancreatic Neoplasms 1

Interventions

Denosumab 7Zoledronic Acid 2Vitamin D 2Indocyanine Green 2gentamicin-polymethylmethacrylate bead 1fludarabine 1aldesleukin 1Nivolumab 1Ipilimumab 1Dasatinib 1Cyclophosphamide 1Calcium 1CTLA-4 Antigen 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

7 trials
RecentStart dateEnrollment
Interventional × Giant Cell Tumor of Bone × Denosumab × Clear all
NCT04586660 2025-10-01

Study of XGEVA® (Denosumab) in Chinese Adults and Skeletally Mature Adolescents With Giant Cell Tumor of the Bone

Amgen

Phase 4 Active not recruiting
36 enrolled

Giant Cell Tumor of Bone

NCT03301857 2024-05-20

Long-term Safety Follow-up of Subjects With Giant Cell Tumor of Bone Treated With Denosumab in Study 20062004

Amgen

Phase 4 Completed
85 enrolled 13 charts

Giant Cell Tumor of Bone

NCT05813665 2023-04-19

A Study to Evaluate the Efficacy and Safety of Narlumosbart (JMT103) in Patients With Giant Cell Tumor of Bone

Shanghai JMT-Bio Inc.

Phase 3 Not yet recruiting
146 enrolled

Giant Cell Tumor of Bone

NCT00396279 2022-11-08

Safety and Efficacy Study of Denosumab in Patients With Recurrent or Unresectable Giant Cell Tumor of Bone

Amgen

Phase 2 Completed
37 enrolled 13 charts

Giant Cell Tumor of Bone

NCT00680992 2022-09-22

Study of Denosumab in Subjects With Giant Cell Tumor of Bone

Amgen

Phase 2 Completed
535 enrolled 16 charts

Giant Cell Tumors, Neoplasms, Giant Cell Tumor of Bone

NCT03620149 2021-01-06

REDUCE

European Organisation for Research and Treatment of Cancer - EORTC

Phase 2 Terminated
2 enrolled

Giant Cell Tumor of Bone

NCT03259152 2017-08-24

D-Gct

Hebei Medical University Third Hospital

Phase 3 Unknown
30 enrolled

Giant Cell Tumor of Bone

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