Announcements Trials
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Phase

Phase 2 1Phase 1/2 1Phase 1 1

Status

Not yet recruiting 1Enrolling by invitation 1Active not recruiting 1

Sponsor Class

OTHER 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Lymphoid 1

Conditions

Burkitt Lymphoma 12Precursor Cell Lymphoblastic Leukemia-Lymphoma 7Lung Neoplasms 6Breast Neoplasms 6Meningeal Carcinomatosis 5Leukemia, Myeloid, Acute 5Carcinoma, Non-Small-Cell Lung 5Lymphoma, Large B-Cell, Diffuse 4Leukemia, Biphenotypic, Acute 4Myelodysplastic Syndromes 3Glioblastoma 3Astrocytoma 3Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 2Lymphoma 2Glioma 2Brain Neoplasms 2Uveal Melanoma 1Rhabdomyosarcoma 1Oligodendroglioma 1Nevus 1Neoplastic Cells, Circulating 1Neoplasm Recurrence, Local 1Multiple Myeloma 1Meningioma 1Meningeal Neoplasms 1Melanoma 1Lymphoma, T-Cell, Peripheral 1Lymphoma, T-Cell, Cutaneous 1Lymphoma, T-Cell 1

Interventions

Temozolomide 100Radiotherapy 49Magnetic Resonance Spectroscopy 38Radiation 28Specimen Handling 25pembrolizumab 22Bevacizumab 22Lomustine 16Nivolumab 14Surgical Procedures, Operative 10atezolizumab 8Cyclophosphamide 8Biopsy 8abemaciclib 7Ipilimumab 7fludarabine 6Radiotherapy, Intensity-Modulated 6Carboplatin 6Aminolevulinic Acid 6olaparib 5Metformin 5Drug Therapy 5Diet, Ketogenic 5Dianhydrogalactitol 5poly ICLC 4cemiplimab 4Radiosurgery 4Photons 4Leukapheresis 4Immunoglobulin G 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Glioblastoma × Spinal Puncture × 1 year × Clear all
NCT03919071 2026-05-27

Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma

National Cancer Institute (NCI)

Phase 2 Active not recruiting
58 enrolled
CNS

Astrocytoma, Glioblastoma, Glioma

NCT07468136 2026-04-13

Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas

Mayo Clinic

Phase 1/2 Not yet recruiting
33 enrolled
CNSLymphoid

Astrocytoma, Glioblastoma, Glioma, Lymphoma, Follicular, Oligodendroglioma

NCT06896110 2025-06-26

Intrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade Glioma

University of Iowa

Phase 1 Enrolling by invitation
34 enrolled
CNS

Astrocytoma, Glioblastoma

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