Announcements Trials
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Phase

Phase 1 2Phase 2 1Phase 1/2 1

Status

Recruiting 3Suspended 1

Sponsor Class

OTHER 2NIH 2

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 4

Conditions

Neoplasm Metastasis 36Leukemia, Myeloid, Acute 32Multiple Myeloma 27Lymphoma 23Breast Neoplasms 18Prostatic Neoplasms 17Pancreatic Neoplasms 17Colorectal Neoplasms 17Lymphoma, Large B-Cell, Diffuse 15Burkitt Lymphoma 15Myelodysplastic Syndromes 14Leukemia, Lymphocytic, Chronic, B-Cell 14Triple Negative Breast Neoplasms 12Ovarian Neoplasms 12Precursor Cell Lymphoblastic Leukemia-Lymphoma 11Melanoma 11Lung Neoplasms 11Sarcoma 10Lymphoma, T-Cell 9Glioma 9Carcinoma, Non-Small-Cell Lung 9Neuroblastoma 8Neoplasms 8Fallopian Tube Neoplasms 8Carcinoma, Renal Cell 8Squamous Cell Carcinoma of Head and Neck 7Lymphoma, Non-Hodgkin 7Lymphoma, Follicular 7Leukemia, Biphenotypic, Acute 7Endometrial Neoplasms 7

Interventions

Temozolomide 40Magnetic Resonance Spectroscopy 19Radiotherapy 18Specimen Handling 14Radiation 12Bevacizumab 11Lomustine 9pembrolizumab 6fludarabine 5Surgical Procedures, Operative 5atezolizumab 4Nivolumab 4Ipilimumab 4Cyclophosphamide 4Carboplatin 4Biopsy 4cemiplimab 3azeliragon 3Immunoglobulin G 3Disulfides 3Aminolevulinic Acid 3veliparib 2trametinib 2rocakinogene sifuplasmid 2poly ICLC 2olaparib 2lutetium Lu 177 dotatate 2durvalumab 2dabrafenib 2contrast agent BR1 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Glioblastoma × Biopsy × 90 days × Clear all
NCT07416188 2026-06-05

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

National Institutes of Health Clinical Center (CC)

Phase 1/2 Recruiting
40 enrolled
CNS

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neoplasms by Histologic Type, Neoplasms, Nerve Tissue, Recurrence, Central Nervous System Neoplasms

NCT06325683 2026-06-03

Anti-Lag-3 (Relatlimab) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma

National Cancer Institute (NCI)

Phase 2 Suspended
184 enrolled
CNS

Glioblastoma

NCT07544992 2026-05-06

Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas

City of Hope Medical Center

Phase 1 Recruiting
24 enrolled
CNS

Astrocytoma, Glioblastoma

NCT07560865 2026-05-01

First-in Cancer-Type Phase I Study of FT536 for Recurrent WHO Grade 4 Astrocytoma

Masonic Cancer Center, University of Minnesota

Phase 1 Recruiting
9 enrolled
CNS

Astrocytoma, Glioblastoma, Disease Progression

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