Clinical Trials

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT04762069 2026-04-15

A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma Multiforme

252 enrolled

Brain Neoplasms, Glioblastoma

NCT06325683 2026-04-15

Anti-Lag-3 (Relatlimab) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma

Phase 2 Suspended

184 enrolled

Glioblastoma

NCT06805305 2026-04-14

DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)

180 enrolled

Glioblastoma

NCT07326566 2026-04-14

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

162 enrolled

Brain Neoplasms, Central Nervous System Diseases, Glioblastoma, Glioma

NCT02800486 2026-04-13

Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA

37 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT03581292 2026-04-13

Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations

38 enrolled 13 charts

Astrocytoma, Glioblastoma, Glioma

NCT03919071 2026-04-13

Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma

58 enrolled

Astrocytoma, Glioblastoma, Glioma

NCT04145115 2026-04-13

A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden

37 enrolled

Astrocytoma, Glioblastoma

NCT07521657 2026-04-13

NF118

55 enrolled

Glioblastoma, Glioma, Neurofibromatosis 1

NCT07301268 2026-04-08

GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

36 enrolled

Astrocytoma, Glioblastoma, Gliosarcoma

NCT07511725 2026-04-06

PRISM

38 enrolled

Glioblastoma

NCT06319027 2026-04-03

GABLE

100 enrolled

Glioblastoma

NCT04729959 2026-04-01

Testing the Addition of the Immune Therapy Drugs, Tocilizumab and Atezolizumab, to Radiation Therapy for Recurrent Glioblastoma

59 enrolled

Astrocytoma, Glioblastoma

NCT05986851 2026-03-31

Azeliragon in MGMT Unmethylated Glioblastoma

30 enrolled

Glioblastoma

NCT02455557 2026-03-30

SurVaxM Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

66 enrolled 11 charts

Glioblastoma, Gliosarcoma

NCT04559230 2026-03-30

Sacituzumab Govitecan in Recurrent Glioblastoma

32 enrolled

Glioblastoma

NCT01743950 2026-03-25

A Phase II Study of Pulse Reduced Dose Rate Radiation Therapy With Bevacizumab

Phase 2 Terminated

49 enrolled 19 charts

Glioblastoma, Glioma

NCT03197506 2026-03-25

Pembrolizumab and Standard Therapy in Treating Patients With Glioblastoma

52 enrolled 19 charts

Glioblastoma, Gliosarcoma

NCT04574856 2026-03-25

Multiparametric MR-Guided High Dose Adaptive Radiotherapy With Concurrent Temozolomide in Patients With Newly Diagnosed Glioblastoma

30 enrolled

Glioblastoma

NCT05843253 2026-03-20

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

120 enrolled

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT07225621 2026-03-19

Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed Glioblastoma

103 enrolled

Glioblastoma

NCT07476794 2026-03-17

TEMPO

118 enrolled

Glioblastoma

NCT05753007 2026-03-16

A Clinical Trial of a Hemp-Derived, High Cannabidiol Product for Anxiety in Glioblastoma Patients

Phase 2 Terminated

2 enrolled 13 charts

Glioblastoma

NCT03475186 2026-03-13

Testing Ramipril to Prevent Memory Loss in People With Glioblastoma

Phase 2 Completed

75 enrolled 47 charts

Brain Neoplasms, Glioblastoma, Cognitive Dysfunction

NCT07297212 2026-03-12

A Clinical Trial Testing the Safety of the Investigational Drug Pumitamig (BNT327) and How Well it Works in Patients With Recurrent Glioblastoma

75 enrolled

Brain Neoplasms, Glioblastoma

NCT04044937 2026-03-11

UC-GlioFET

Phase 2 Completed

143 enrolled

Brain Neoplasms, Glioblastoma

NCT07462507 2026-03-10

Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1

104 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT05463848 2026-03-04

Surgical Pembro +/- Olaparib w TMZ for rGBM

78 enrolled

Glioblastoma

NCT05607407 2026-03-04

Methimazole in Patients With Progressive Glioblastoma

19 enrolled

Glioblastoma, Glioma

NCT07439172 2026-02-27

PRC

70 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT01068782 2026-02-25

Multiple Doses and Regimens of Cabozantinib in Subjects With Grade IV Astrocytic Tumors in First or Second Relapse

Phase 2 Terminated

19 enrolled 10 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT06058988 2026-02-23

Trastuzumab Deruxtecan (T-DXd) for People With Brain Cancer

30 enrolled

Brain Neoplasms, Glioblastoma, Neoplasm Metastasis, Meningeal Carcinomatosis

NCT03212274 2026-02-19

Olaparib in Treating Patients With Advanced Glioma, Cholangiocarcinoma, or Solid Tumors With IDH1 or IDH2 Mutations

89 enrolled

CNSGastrointestinal

Glioblastoma, Glioma, Cholangiocarcinoma

NCT04765514 2026-02-13

Chemoradiotherapy Versus Chemotherapy for Elderly and Frail GBM Patients

107 enrolled

Glioblastoma

NCT07263438 2026-02-13

Phenix

59 enrolled

Glioblastoma, Recurrence

NCT06061809 2026-02-12

N-803 and PD-L1 t-haNK Combined With Bevacizumab for Recurrent or Progressive Glioblastoma

34 enrolled

Glioblastoma

NCT04482933 2026-02-10

HSV G207 With a Single Radiation Dose in Children With Recurrent High-Grade Glioma

Phase 2 Withdrawn

Brain Neoplasms, Glioblastoma, Glioma, Herpes Simplex, Neoplasms, Virus Diseases

NCT04485949 2026-02-10

A Phase 2b Clinical Study With a Combination Immunotherapy in Newly Diagnosed Patients With Glioblastoma

93 enrolled

Glioblastoma

NCT03405792 2026-02-06

2-THE-TOP

40 enrolled 11 charts

Glioblastoma

NCT05653622 2026-02-04

SIB-DOPA

75 enrolled

Glioblastoma

NCT05653635 2026-02-04

ReciDOPA

54 enrolled

Glioblastoma

NCT05781321 2026-02-03

Short Course Radiotherapy for the Treatment of Patients With Glioblastoma, SAGA Study

170 enrolled

Glioblastoma

NCT02394626 2026-02-02

RESURGE

120 enrolled

Glioblastoma

NCT05629702 2026-01-30

ARISTOCRAT

120 enrolled

Brain Neoplasms, Marijuana Abuse, Glioblastoma, Recurrence

NCT05683808 2026-01-30

VTE-POG

40 enrolled

CNSClassical hematology

Astrocytoma, Glioblastoma, Glioma, Venous Thromboembolism

NCT04752813 2026-01-26

A Study of BPM31510 With Vitamin K1 in Subjects With Newly Diagnosed Glioblastoma (GB)

50 enrolled

Glioblastoma

NCT07356973 2026-01-26

OPTICAL

147 enrolled

Glioblastoma

NCT07365280 2026-01-26

Neoantigen-Pulsed Autologous Dendritic Cell Vaccine Combined With Temozolomide for Newly Diagnosed Glioblastoma

78 enrolled

Glioblastoma

NCT07364786 2026-01-23

AFGBMBiop

10 enrolled