Announcements Trials
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Phase

Phase 1/2 2Phase 2 1

Status

Completed 2Terminated 1

Sponsor Class

OTHER 2INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Sarcoma 1

Conditions

Breast Neoplasms 9Neoplasm Metastasis 7Brain Neoplasms 4Squamous Cell Carcinoma of Head and Neck 3Glioblastoma 3Carcinoma, Non-Small-Cell Lung 3Triple Negative Breast Neoplasms 2Recurrence 2Prostatic Neoplasms 2Hereditary Sensory and Autonomic Neuropathies 2Tongue Neoplasms 1Thymoma 1Skin Neoplasms 1Salivary Gland Neoplasms 1Neoplasms 1Nasopharyngeal Neoplasms 1Melanoma 1Lymphoma, Non-Hodgkin 1Lymphoma, Mantle-Cell 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, Follicular 1Lymphoma 1Lung Neoplasms 1Leukemia, Myeloid, Acute 1Leukemia, Lymphocytic, Chronic, B-Cell 1Laryngeal Neoplasms 1Hypoxia 1Hypopharyngeal Neoplasms 1Hematologic Neoplasms 1Gliosarcoma 1

Interventions

Temozolomide 115Bevacizumab 72Radiotherapy 52Radiation 23Erlotinib Hydrochloride 13Lomustine 12pembrolizumab 11Magnetic Resonance Spectroscopy 11Vorinostat 10Nivolumab 10Surgical Procedures, Operative 9Irinotecan 9Sorafenib 8Radiotherapy, Intensity-Modulated 8Radiotherapy, Conformal 7Immunoglobulin G 7Everolimus 7Drug Therapy 7Disulfides 7Radiosurgery 6Granulocyte-Macrophage Colony-Stimulating Factor 6Carmustine 6antineoplaston AS 2-1 5antineoplaston A10 5Sirolimus 5Cilengitide 5veliparib 4veledimex 4temsirolimus 4selinexor 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Has results × Glioblastoma × NVP-BKM120 × Clear all
NCT01349660 2020-06-17

Combination of BKM120 and Bevacizumab in Refractory Solid Tumors and Relapsed/Refractory Glioblastoma Multiforme

SCRI Development Innovations, LLC

Phase 1/2 Completed
88 enrolled 13 charts
CNS

Glioblastoma

NCT01339052 2019-03-19

Phase II Study of BKM120 for Subjects With Recurrent Glioblastoma

Dana-Farber Cancer Institute

Phase 2 Completed
65 enrolled 30 charts
CNS

Brain Neoplasms, Glioblastoma

NCT01870726 2018-05-30

Safety and Efficacy of INC280 and Buparlisib (BKM120) in Patients With Recurrent Glioblastoma

Novartis

Phase 1/2 Terminated
43 enrolled 22 charts
CNSSarcoma

Brain Neoplasms, Glioblastoma, Gliosarcoma

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