Clinical Trials Browser

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NCT01743950 2026-03-25

A Phase II Study of Pulse Reduced Dose Rate Radiation Therapy With Bevacizumab

Phase 2 Terminated

49 enrolled 19 charts

Glioblastoma, Glioma

NCT05753007 2026-03-16

A Clinical Trial of a Hemp-Derived, High Cannabidiol Product for Anxiety in Glioblastoma Patients

Phase 2 Terminated

2 enrolled 13 charts

Glioblastoma

NCT01068782 2026-02-25

Multiple Doses and Regimens of Cabozantinib in Subjects With Grade IV Astrocytic Tumors in First or Second Relapse

Phase 2 Terminated

19 enrolled 10 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT02942264 2026-02-23

Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma

Phase 1/2 Terminated

53 enrolled 22 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Recurrence, Gliosarcoma

NCT04825275 2026-01-23

Neuro-pharmacological Properties of Repurposed Posaconazole in Glioblastoma: A Phase 0 Clinical Trial

Phase EARLY_PHASE1 Terminated

7 enrolled 12 charts

Brain Neoplasms, Glioblastoma

NCT05267106 2025-12-30

FIGHT-209

Phase 2 Terminated

83 enrolled 18 charts

Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT04209790 2025-11-10

NeoGlio

Phase 2 Terminated

2 enrolled 7 charts

Glioblastoma, Glioma

NCT04424966 2025-10-24

Infigratinib in Recurrent High-Grade Glioma Patients

Phase EARLY_PHASE1 Terminated

7 enrolled 18 charts

Glioblastoma, Glioma

NCT02711137 2025-10-21

Open-Label Safety and Tolerability Study of INCB057643 in Subjects With Advanced Malignancies

Phase 1/2 Terminated

137 enrolled 31 charts

BreastCNSGastrointestinalGenitourinaryGynecologicLymphoidMyeloidOther hematologic neoplasmPlasma cellThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Glioblastoma, Leukemia, Lymphoma, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Lymphoma, Large B-Cell, Diffuse, Primary Myelofibrosis

NCT03868943 2025-10-21

JAZZ

Phase 2 Terminated

2 enrolled 5 charts

Glioblastoma, Glioma

NCT03347617 2025-09-09

Ferumoxytol MRI in Assessing Response to Pembrolizumab in Patients With Glioblastoma

Phase 2 Terminated

52 enrolled 15 charts

Glioblastoma

NCT03330197 2025-08-12

A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG

Phase 1/2 Terminated

6 enrolled 14 charts

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Glioma

NCT03018288 2025-08-08

Radiation Therapy Plus Temozolomide and Pembrolizumab With and Without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)

Phase 2 Terminated

90 enrolled 24 charts

Glioblastoma, Glioma

NCT04406272 2025-06-10

VB-111 in Surgically Accessible Recurrent/Progressive GBM

Phase 2 Terminated

15 enrolled 14 charts

Glioblastoma

NCT05297864 2025-05-23

OU-SCC-PI-4G

Phase 2 Terminated

15 enrolled 13 charts

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT04006119 2025-04-18

Study of Ad-RTS-hIL-12 + Veledimex in Combination With Cemiplimab in Subjects With Recurrent or Progressive Glioblastoma

Phase 2 Terminated

40 enrolled 14 charts

Glioblastoma

NCT01814813 2025-01-24

Vaccine Therapy With Bevacizumab Versus Bevacizumab Alone in Treating Patients With Recurrent Glioblastoma Multiforme That Can Be Removed by Surgery

Phase 2 Terminated

90 enrolled 13 charts

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT02525692 2024-12-24

Oral ONC201 in Adult Recurrent Glioblastoma

Phase 2 Terminated

84 enrolled 14 charts 1 FDA

Glioblastoma

NCT04421378 2024-12-16

A Study of Selinexor in Combination With Standard of Care Therapy for Newly Diagnosed or Recurrent Glioblastoma

Phase 1/2 Terminated

74 enrolled 23 charts

Glioblastoma

NCT02372409 2024-11-01

Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors

Phase 2 Terminated

6 enrolled 10 charts

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma, Optic Nerve Glioma

NCT03973918 2024-10-31

BRAF

Phase 2 Terminated

5 enrolled 15 charts

Astrocytoma, Glioblastoma, Glioma, Gliosarcoma

NCT03296696 2024-10-29

Study of AMG 596 in Patients With EGFRvIII Positive Glioblastoma

Phase 1 Terminated

30 enrolled 29 charts

Glioblastoma, Glioma

NCT03363659 2024-10-03

Disulfiram and Copper Gluconate With Temozolomide in Unmethylated Glioblastoma Multiforme

Phase 2 Terminated

15 enrolled 9 charts

Glioblastoma

NCT00555399 2024-08-22

Vorinostat, Isotretinoin and Temozolomide in Adults With Recurrent Glioblastoma Multiforme (GBM)

Phase 1/2 Terminated

55 enrolled 19 charts

Glioblastoma

NCT03250299 2024-06-24

Microtubule-Targeted Agent BAL101553 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Phase 1 Terminated

26 enrolled 17 charts

Brain Neoplasms, Glioblastoma

NCT03927222 2024-04-08

I-ATTAC

Phase 2 Terminated

6 enrolled 7 charts

Glioblastoma, Tetanus

NCT03705351 2024-03-04

Tumor Treating Fields With Chemoradiation in Newly Diagnosed GBM

Phase 1 Terminated

7 enrolled 12 charts

Brain Neoplasms, Glioblastoma

NCT02829723 2024-01-18

A Study of BLZ945 Single Agent or BLZ945 in Combination With PDR001 in Advanced Solid Tumors

Phase 1/2 Terminated

192 enrolled 77 charts

Glioblastoma

NCT02168270 2023-11-24

Temozolomide and Ascorbic Acid in Treating Patients With Recurrent High-Grade Glioma

Phase 1 Terminated

4 enrolled 6 charts

Astrocytoma, Glioblastoma, Oligodendroglioma, Gliosarcoma

NCT01721577 2023-05-22

AXL1717

Phase 1/2 Terminated

10 enrolled 8 charts

Astrocytoma, Ependymoma, Glioblastoma, Oligodendroglioma, Gliosarcoma

NCT02664363 2023-02-17

ExCeL

Phase 1 Terminated

3 enrolled 8 charts

Glioblastoma, Gliosarcoma

NCT03430791 2023-02-02

Trial of Combination Tumor Treating Fields (TTF; Optune), Nivolumab Plus/Minus Ipilimumab for Recurrent Glioblastoma

Phase 2 Terminated

5 enrolled 10 charts

Glioblastoma

NCT01986348 2023-01-26

KING

Phase 2 Terminated

76 enrolled 16 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT03119064 2022-12-13

329

Phase 1/2 Terminated

12 enrolled 13 charts

Glioblastoma

NCT02885324 2022-10-06

Pilot Study of Cabozantinib for Recurrent or Progressive Central Nervous System Tumors in Children

Phase 2 Terminated

4 enrolled 6 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT03022578 2022-08-10

Laser Interstitial Thermal Therapy and Lomustine in Treating Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma

Phase 2 Terminated

7 enrolled 9 charts

Astrocytoma, Glioblastoma

NCT01884740 2022-08-09

Intraarterial Infusion Of Erbitux and Bevacizumab For Relapsed/Refractory Intracranial Glioma In Patients Under 22

Phase 1/2 Terminated

13 enrolled 6 charts

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT02663271 2022-06-23

TTFields and Pulsed Bevacizumab for Recurrent Glioblastoma

Phase 2 Terminated

10 enrolled 13 charts

Glioblastoma, Glioma

NCT00479765 2022-06-22

A Phase 1 / 2 Dose Escalation Study of Locally-Administered OncoGel™ in Subjects With Recurrent Glioma

Phase 1/2 Terminated

4 enrolled 5 charts

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Recurrence

NCT02864368 2022-06-09

PERFORMANCE

Phase 1 Terminated

27 enrolled 13 charts

Glioblastoma

NCT00669669 2022-05-18

O6-Benzylguanine-Mediated Tumor Sensitization With Chemoprotected Autologous Stem Cell in Treating Patients With Malignant Gliomas

Phase 1/2 Terminated

12 enrolled 13 charts

Glioblastoma, Gliosarcoma

NCT01925573 2022-02-03

Optune(NOVOTTF-100A)+ Bevacizumab+ Hypofractionated Stereotactic Irradiation Bevacizumab-Naive Recurrent Glioblastoma (GCC 1344)

Phase NA Terminated

7 enrolled 9 charts

Brain Neoplasms, Glioblastoma

NCT01110876 2021-08-25

Phase I / II Vorinostat, Erlotinib and Temozolomide for Recurrent Glioblastoma Multiforme (GBM)

Phase 1/2 Terminated

21 enrolled 8 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT02765165 2021-07-23

Phase 1/2 Study of USL311 +/- Lomustine in Advanced Solid Tumors or Relapsed/Recurrent Glioblastoma Multiforme (GBM)

Phase 1/2 Terminated

26 enrolled 20 charts

Brain Neoplasms, Glioblastoma, Neoplasms, Recurrence

NCT03393000 2021-07-22

INTACT

Phase 3 Terminated

19 enrolled 8 charts

Glioblastoma

NCT02743078 2021-06-02

Optune® Plus Bevacizumab in Bevacizumab-Refractory Recurrent Glioblastoma

Phase 2 Terminated

3 enrolled 10 charts

Glioblastoma, Glioma, Gliosarcoma

NCT03419403 2021-04-14

UNITE Study: Understanding New Interventions With GBM ThErapy

Phase 3 Terminated

40 enrolled 16 charts

Glioblastoma, Neoplasms

NCT02340156 2021-03-03

Phase II Study of Combined Temozolomide and SGT-53 for Treatment of Recurrent Glioblastoma

Phase 2 Terminated

1 enrolled 8 charts

Glioblastoma

NCT02255461 2021-03-02

Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

Phase 1 Terminated

35 enrolled 28 charts

Astrocytoma, Glioblastoma, Medulloblastoma, Oligodendroglioma, Choroid Plexus Neoplasms, Neoplasms, Neuroepithelial

NCT02296476 2021-01-26

MK-8628-002

Phase 2 Terminated

12 enrolled 17 charts

Glioblastoma