Announcements Trials
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Phase

Phase 1 2Phase EARLY_PHASE1 1

Status

Completed 2Recruiting 1

Sponsor Class

OTHER 2INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3

Conditions

Carcinoma, Non-Small-Cell Lung 53Neoplasms 23Breast Neoplasms 15Squamous Cell Carcinoma of Head and Neck 13Lung Neoplasms 12Head and Neck Neoplasms 11Neoplasm Metastasis 8Carcinoma, Squamous Cell 7Pancreatic Neoplasms 6Colorectal Neoplasms 6Stomach Neoplasms 5Esophageal Squamous Cell Carcinoma 5Prostatic Neoplasms 4Multiple Myeloma 4Esophageal Neoplasms 4Lymphoma 3Hematologic Neoplasms 3Glioblastoma 3Brain Neoplasms 3Adenocarcinoma 3Urinary Bladder Neoplasms 2Non-small-cell Lung Cancer With Somatic EGFR Mutations 2Melanoma 2Glioma 2Colonic Neoplasms 2Adenocarcinoma of Lung 2Uterine Neoplasms 1Uterine Cervical Neoplasms 1Urologic Neoplasms 1Urethral Neoplasms 1

Interventions

Temozolomide 393Radiotherapy 196Bevacizumab 156Radiation 77Magnetic Resonance Spectroscopy 68Lomustine 47Surgical Procedures, Operative 42Carmustine 41pembrolizumab 39Irinotecan 38Nivolumab 32Specimen Handling 27Carboplatin 27Radiosurgery 24Erlotinib Hydrochloride 24Chemotherapy, Adjuvant 23Radiotherapy, Intensity-Modulated 22Drug Therapy 20Cyclophosphamide 20Aminolevulinic Acid 20O(6)-benzylguanine 17sargramostim 16Radiotherapy, Conformal 15temsirolimus 14Granulocyte-Macrophage Colony-Stimulating Factor 14Everolimus 14Vorinostat 13Sorafenib 13poly ICLC 12atezolizumab 12

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Interventional × Glioblastoma × Afatinib × Clear all
NCT05432518 2025-04-25

Pilot Trial for Treatment of Recurrent Glioblastoma

AHS Cancer Control Alberta

Phase EARLY_PHASE1 Recruiting
10 enrolled
CNS

Glioblastoma, Recurrence

NCT02423525 2022-03-10

Safety Study of Afatinib for Brain Cancer

Saint John's Cancer Institute

Phase 1 Completed
24 enrolled
CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Meningioma, Oligodendroglioma, Meningeal Carcinomatosis

NCT00977431 2019-02-18

Open Label Trial to Explore Safety of Combining Afatinib (BIBW 2992) and Radiotherapy With or Without Temozolomide in Newly Diagnosed Glioblastoma Multiform

Boehringer Ingelheim

Phase 1 Completed
36 enrolled 16 charts
CNS

Glioblastoma

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