Announcements Trials
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Phase

Phase NA 3Phase 2 3Phase 1 3Phase EARLY_PHASE1 1Phase 1/2 1

Status

Recruiting 2Active not recruiting 1

Sponsor Class

OTHER 3

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3

Conditions

Neoplasm Metastasis 33Leukemia, Myeloid, Acute 24Melanoma 14Colorectal Neoplasms 14Breast Neoplasms 14Multiple Myeloma 13Myelodysplastic Syndromes 12Leukemia, Lymphocytic, Chronic, B-Cell 12Pancreatic Neoplasms 10Lymphoma, Follicular 10Prostatic Neoplasms 9Precursor Cell Lymphoblastic Leukemia-Lymphoma 9Lymphoma, Large B-Cell, Diffuse 8Triple Negative Breast Neoplasms 7Lymphoma, Non-Hodgkin 7Lymphoma, Mantle-Cell 7Lung Neoplasms 7Burkitt Lymphoma 7Ovarian Neoplasms 6Lymphoma, B-Cell, Marginal Zone 6Stomach Neoplasms 5Sarcoma 5Lymphoma, T-Cell, Cutaneous 5Lymphoma, T-Cell 5Lymphoma, B-Cell 5Lymphoma 5Leukemia, Biphenotypic, Acute 5Carcinoma, Renal Cell 5Carcinoma, Non-Small-Cell Lung 5Unspecified Adult Solid Tumor, Protocol Specific 4

Interventions

Temozolomide 107Radiotherapy 60Radiation 28Bevacizumab 19Magnetic Resonance Spectroscopy 16Nivolumab 15Surgical Procedures, Operative 12Irinotecan 11Cyclophosphamide 10Specimen Handling 9Chemotherapy, Adjuvant 9Radiotherapy, Intensity-Modulated 8Radiosurgery 8O(6)-benzylguanine 8Carmustine 8poly ICLC 7pembrolizumab 7motexafin gadolinium 7fludarabine 7Leukapheresis 7Flucytosine 7sargramostim 6Radiotherapy, Conformal 6Erlotinib Hydrochloride 6Lomustine 5Ipilimumab 5Imiquimod 5Imatinib Mesylate 5Hydroxyurea 5Granulocyte-Macrophage Colony-Stimulating Factor 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 1 × Glioblastoma × Biopsy × Clear all
NCT07544992 2026-05-06

Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas

City of Hope Medical Center

Phase 1 Recruiting
24 enrolled
CNS

Astrocytoma, Glioblastoma

NCT07560865 2026-05-01

First-in Cancer-Type Phase I Study of FT536 for Recurrent WHO Grade 4 Astrocytoma

Masonic Cancer Center, University of Minnesota

Phase 1 Recruiting
9 enrolled
CNS

Astrocytoma, Glioblastoma, Disease Progression

NCT07031765 2025-12-18

Peds CHAMP1ON

University of Florida

Phase 1 Active not recruiting
12 enrolled
CNS

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma

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