Announcements Trials
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Phase

Phase 1/2 2Phase 1 2

Status

Completed 3Unknown 1

Sponsor Class

INDUSTRY 6OTHER 4

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 4Sarcoma 2

Conditions

Glioma 4Glioblastoma 4Brain Neoplasms 3Astrocytoma 3Oligodendroglioma 2Gliosarcoma 2

Interventions

Temozolomide 264Radiotherapy 119Bevacizumab 105Magnetic Resonance Spectroscopy 59Radiation 47pembrolizumab 30Irinotecan 28Surgical Procedures, Operative 23Lomustine 21Specimen Handling 19Nivolumab 19Radiosurgery 18Carmustine 18Aminolevulinic Acid 16Erlotinib Hydrochloride 15Drug Therapy 15Blood Specimen Collection 14Radiotherapy, Intensity-Modulated 13O(6)-benzylguanine 13Chemotherapy, Adjuvant 13Carboplatin 13Filgrastim 11Cyclophosphamide 11sargramostim 10poly ICLC 10atezolizumab 10Thalidomide 10Etoposide 10Ipilimumab 9Everolimus 9

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
OTHER × Glioblastoma × Flucytosine × Clear all
NCT06562621 2024-08-20

Clinical Study on the Safety and Efficacy of Novel Oncolytic Virus in the Treatment of Recurrent Malignant Glioma

Beijing Neurosurgical Institute

Phase 1/2 Completed
38 enrolled
CNS

Glioblastoma, Glioma

NCT02015819 2021-10-20

Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade Gliomas

City of Hope Medical Center

Phase 1 Completed
16 enrolled 16 charts
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma, Gliosarcoma

NCT01172964 2017-11-09

A Pilot Feasibility Study of Oral 5-Fluorocytosine and Genetically-Modified Neural Stem Cells Expressing E.Coli Cytosine Deaminase for Treatment of Recurrent High Grade Gliomas

City of Hope Medical Center

Phase 1 Completed
15 enrolled
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT03294486 2017-11-06

ONCOVIRAC

Assistance Publique - Hôpitaux de Paris

Phase 1/2 Unknown
78 enrolled
CNS

Brain Neoplasms, Glioblastoma

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