Announcements Trials
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Phase

Phase 1/2 2Phase 1 1

Status

Completed 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1CNS 1

Conditions

Melanoma 25Leukemia, Lymphocytic, Chronic, B-Cell 10Breast Neoplasms 10Recurrence 9Leukemia, Myeloid, Acute 9Carcinoma, Non-Small-Cell Lung 9Neuroblastoma 8Lymphoma, Non-Hodgkin 8Neoplasms 7Ovarian Neoplasms 6Neoplasm Metastasis 6Leukemia 6Colorectal Neoplasms 6Carcinoma, Renal Cell 6Uveal Melanoma 5Myelodysplastic Syndromes 5Multiple Myeloma 5Lymphoma, Follicular 5Lymphoma 5Lung Neoplasms 5Head and Neck Neoplasms 5Precursor Cell Lymphoblastic Leukemia-Lymphoma 4Lymphoma, Mantle-Cell 4Lymphoma, B-Cell, Marginal Zone 4Lymphoma, B-Cell 4Hematologic Neoplasms 4Carcinoma, Squamous Cell 4Carcinoma, Hepatocellular 4Uterine Cervical Neoplasms 3Unspecified Adult Solid Tumor, Protocol Specific 3

Interventions

Temozolomide 107Radiotherapy 60Radiation 28Bevacizumab 19Magnetic Resonance Spectroscopy 16Nivolumab 15Surgical Procedures, Operative 12Irinotecan 11Cyclophosphamide 10Specimen Handling 9Chemotherapy, Adjuvant 9Radiotherapy, Intensity-Modulated 8Radiosurgery 8O(6)-benzylguanine 8Carmustine 8poly ICLC 7pembrolizumab 7motexafin gadolinium 7fludarabine 7Leukapheresis 7Flucytosine 7sargramostim 6Radiotherapy, Conformal 6Erlotinib Hydrochloride 6Lomustine 5Ipilimumab 5Imiquimod 5Imatinib Mesylate 5Hydroxyurea 5Granulocyte-Macrophage Colony-Stimulating Factor 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1 × Glioblastoma × Interleukin-2 × Clear all
NCT01082926 2015-06-08

Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2

City of Hope Medical Center

Phase 1 Completed
6 enrolled
CNSSarcoma

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Meningioma, Oligodendroglioma, Neuroectodermal Tumors, Primitive, Gliosarcoma

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