Announcements Trials
Browse Landscape

Phase

Phase 2 18Phase 3 12Phase 1/2 5Phase 1 5Phase 2/3 4Phase NA 2Phase EARLY_PHASE1 1

Status

Completed 3Withdrawn 1Recruiting 1

Sponsor Class

INDUSTRY 3OTHER 2

Study Type

Interventional 5

Sponsor

Cancer Type

CNS 5Sarcoma 1

Conditions

Glioblastoma 5Brain Neoplasms 4Glioma 3Central Nervous System Neoplasms 2Astrocytoma 2Oligodendroglioma 1Newly Diagnosed High Grade Glioma 1Neoplasms 1Melanoma 1Medulloblastoma 1Lymphoma, Follicular 1Gliosarcoma 1Familial ependymoma 1Ependymoma 1Drug-Related Side Effects and Adverse Reactions 1

Interventions

Temozolomide 107Radiotherapy 60Radiation 28Bevacizumab 19Magnetic Resonance Spectroscopy 16Nivolumab 15Surgical Procedures, Operative 12Irinotecan 11Cyclophosphamide 10Specimen Handling 9Chemotherapy, Adjuvant 9Radiotherapy, Intensity-Modulated 8Radiosurgery 8O(6)-benzylguanine 8Carmustine 8poly ICLC 7pembrolizumab 7motexafin gadolinium 7fludarabine 7Leukapheresis 7Flucytosine 7sargramostim 6Radiotherapy, Conformal 6Erlotinib Hydrochloride 6Lomustine 5Ipilimumab 5Imiquimod 5Imatinib Mesylate 5Hydroxyurea 5Granulocyte-Macrophage Colony-Stimulating Factor 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase 1 × Glioblastoma × Lomustine × Clear all
NCT07145112 2025-10-09

Laser Interstitial Thermal Therapy (LITT) and Lomustine (CCNU) for Recurrent Glioblastoma

University of California, Davis

Phase 1 Recruiting
20 enrolled
CNS

Glioblastoma

NCT05304663 2024-04-08

GLIOASTRA

Philogen S.p.A.

Phase 1 Withdrawn
CNS

Glioblastoma

NCT01934361 2020-12-09

Phase Ib/II Study of Buparlisib Plus Carboplatin or Lomustine in Patients With Recurrent Glioblastoma Multiforme

Novartis

Phase 1 Completed
35 enrolled
CNS

Glioblastoma

NCT00005796 2015-03-25

Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors

Indiana University

Phase 1 Completed
10 enrolled
CNSSarcoma

Familial ependymoma, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma, Drug-Related Side Effects and Adverse Reactions

NCT00503204 2009-11-25

Phase I : Cediranib in Combination With Lomustine Chemotherapy in Recurrent Malignant Brain Tumour

AstraZeneca

Phase 1 Completed
20 enrolled
CNS

Brain Neoplasms, Glioblastoma, Neoplasms

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