Clinical Trials Browser

Interventional × Glioblastoma × Surgical Procedures, Operative × Clear all

NCT06325683 2026-05-26

Anti-Lag-3 (Relatlimab) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma

Phase 2 Suspended

Glioblastoma

NCT01872221 2026-04-14

STEMRI

Phase NA Completed

Glioblastoma

NCT07301268 2026-04-08

GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

Phase 2 Recruiting

Astrocytoma, Glioblastoma, Gliosarcoma

NCT07515924 2026-04-07

Oral Gallium Maltolate for Recurrent Glioblastoma

Phase EARLY_PHASE1 Not yet recruiting

Glioblastoma

NCT06448286 2026-02-19

PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastoma

Phase 3 Not yet recruiting

Glioblastoma

NCT04606316 2026-02-17

Surgical Nivolumab And Ipilimumab For Recurrent GBM

Phase 1 Active not recruiting

Glioblastoma

NCT05879250 2025-12-30

WP1066 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Phase 2 Recruiting

Glioblastoma

NCT06831526 2025-11-12

Neoadjuvant Chemoradiotherapy With or Without Concurrent Azeliragon in Patients With Newly Diagnosed Glioblastoma

Phase EARLY_PHASE1 Recruiting

Glioblastoma

NCT02981940 2025-09-02

A Study of Abemaciclib in Recurrent Glioblastoma

Phase 2 Active not recruiting

45 enrolled 10 charts

Brain Neoplasms, Glioblastoma

NCT03018288 2025-08-08

Radiation Therapy Plus Temozolomide and Pembrolizumab With and Without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)

Phase 2 Terminated

90 enrolled 24 charts

Glioblastoma, Glioma

NCT04406272 2025-06-10

VB-111 in Surgically Accessible Recurrent/Progressive GBM

Phase 2 Terminated

15 enrolled 14 charts

Glioblastoma

NCT02715609 2025-04-10

Disulfiram/Copper With Concurrent Radiation Therapy and Temozolomide in Patients With Newly Diagnosed Glioblastoma

Phase 1/2 Completed

35 enrolled 16 charts

Glioblastoma

NCT06328036 2024-12-30

Testing the Combination of Anti-cancer Drugs Tiragolumab and Atezolizumab to Improve Outcomes for Patients With Recurrent Glioblastoma

Phase 2 Withdrawn

Glioblastoma

NCT02794883 2022-04-18

Tremelimumab and Durvalumab in Combination or Alone in Treating Patients With Recurrent Malignant Glioma

Phase 2 Completed

36 enrolled 13 charts

Glioblastoma, Glioma

NCT01567202 2020-09-09

Study of DC Vaccination Against Glioblastoma

Phase 2 Unknown

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms

NCT00047073 2020-08-03

Sirolimus in Treating Patients With Glioblastoma Multiforme

Phase 1/2 Completed

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT03480867 2019-08-14

PARADIGMA

Phase 1 Withdrawn

Glioblastoma

NCT01339052 2019-03-19

Phase II Study of BKM120 for Subjects With Recurrent Glioblastoma

Phase 2 Completed

65 enrolled 30 charts

Brain Neoplasms, Glioblastoma

NCT01213407 2016-05-19

GBM-Vax

Phase 2 Completed

Brain Neoplasms, Glioblastoma, Glioma

NCT00003484 2015-04-23

Radiolabeled Monoclonal Antibody Therapy After Radiation Therapy in Treating Patients With Primary Brain Tumors

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Craniopharyngioma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neuroblastoma, Oligodendroglioma, Pinealoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00024570 2014-11-14

Interstitial Infusion of IL13-PE38QQR Cytotoxin in Recurrent Malignant Glioma

Phase 1/2 Completed

Astrocytoma, Glioblastoma, Glioma, Recurrence

NCT00003461 2014-08-21

Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Tumors

Phase 1/2 Completed

Astrocytoma, Brain Neoplasms, Craniopharyngioma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neoplasm Metastasis, Neuroblastoma, Oligodendroglioma, Pinealoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00238303 2014-05-23

Vorinostat in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme

Phase 2 Completed

103 enrolled 10 charts

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT00003842 2013-12-18

IL-4(38-37)-PE38KDEL Immunotoxin in Treating Patients With Recurrent Malignant Astrocytoma

Phase 1 Unknown

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003788 2013-11-06

Surgery, Radiation Therapy, and Chemotherapy With or Without Photodynamic Therapy in Treating Patients With Newly Diagnosed or Recurrent Malignant Supratentorial Gliomas

Phase 3 Unknown

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003410 2013-06-26

Motexafin Gadolinium With MRI-Guided Surgery in Treating Patients With High-Grade Gliomas

Phase 1 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003876 2013-06-26

Internal Radiation Therapy Plus Carmustine Implants in Treating Patients With Recurrent or Refractory Malignant Glioma

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00870181 2013-06-25

HGG-01

Phase 2 Completed

Glioblastoma

NCT00003574 2013-06-21

Radiation Therapy in Treating Patients With Progressive or Recurrent Malignant Brain Tumors

Phase 2 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00004262 2013-06-04

Radiation Therapy and Gadolinium Texaphyrin in Treating Patients With Supratentorial Glioblastoma Multiforme

Phase 1 Completed

Glioblastoma, Gliosarcoma

NCT00004024 2013-04-05

Biological Therapy Following Surgery and Radiation Therapy in Treating Patients With Primary or Recurrent Astrocytoma or Oligodendroglioma

Phase 2 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Glioma, Subependymal, Gliosarcoma

NCT00003463 2013-02-18

Carmustine Wafers Plus Irinotecan in Treating Patients With Recurrent Supratentorial High Grade Gliomas

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00110032 2013-01-16

Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain Tumors

Phase 1 Terminated

Astrocytoma, Craniopharyngioma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Oligodendroglioma, Pinealoma, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

NCT00430079 2013-01-16

Use of EF5 to Measure the Oxygen Level in Tumor Cells of Patients Undergoing Surgery or Biopsy for Newly Diagnosed Supratentorial Malignant Glioma

Phase NA Terminated

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Glioma, Subependymal, Gliosarcoma

NCT01637753 2012-07-11

Safety and Efficacy Study of Intracranially Implanted Carmustine to Treat Recurrent Malignant Glioma

Phase NA Unknown

Astrocytoma, Glioblastoma, Oligodendroglioma

NCT00515086 2011-09-22

Study of Everolimus (RAD001) in Patients With Recurrent Glioblastoma Multiforme (GBM)

Phase 2 Terminated

41 enrolled 11 charts

Dyschromatosis symmetrica hereditaria 1, Glioblastoma

NCT00089427 2011-07-04

IL13-PE38QQR Infusion After Tumor Resection, Followed by Radiation Therapy With or Without Temozolomide in Patients With Newly Diagnosed Malignant Glioma

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT00024557 2011-06-06

Histologic Effect/Safety of Pre/Post-Operative IL13-PE38QQR in Recurrent Resectable Supratentorial Malignant Glioma Patients

Phase 1 Completed

Astrocytoma, Glioblastoma, Glioma, Recurrence

NCT00041587 2011-06-06

Pre-operative IL13-PE38QQR in Patients With Recurrent or Progressive Malignant Glioma

Phase 1/2 Completed

Astrocytoma, Glioblastoma, Glioma, Neoplasms

NCT00064779 2011-06-06

Imaging Study of the Distribution of IL13-PE38QQR Infused Before and After Surgery in Adult Patients With Recurrent Malignant Glioma

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00076986 2011-06-06

The PRECISE Trial: Study of IL13-PE38QQR Compared to GLIADEL Wafer in Patients With Recurrent Glioblastoma Multiforme

Phase 3 Completed

Brain Neoplasms, Glioblastoma, Glioma

NCT01181193 2011-03-29

Vitamin D for Treatment of Glioblastoma Multiforme

Phase 1/2 Unknown

Glioblastoma