Clinical Trials Browser

Terminated × Glioblastoma × Temozolomide × Clear all

NCT02942264 2026-02-23

Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma

Phase 1/2 Terminated

53 enrolled 22 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Recurrence, Gliosarcoma

NCT04209790 2025-11-10

NeoGlio

Phase 2 Terminated

2 enrolled 7 charts

Glioblastoma, Glioma

NCT03018288 2025-08-08

Radiation Therapy Plus Temozolomide and Pembrolizumab With and Without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)

Phase 2 Terminated

90 enrolled 24 charts

Glioblastoma, Glioma

NCT01430351 2025-05-07

Temozolomide, Memantine Hydrochloride, Mefloquine, and Metformin Hydrochloride in Treating Patients With Glioblastoma Multiforme After Radiation Therapy

Phase 1 Terminated

Glioblastoma, Gliosarcoma

NCT04397679 2025-01-15

Partial Brain RT, Temozolomide, Chloroquine, and TTF Therapy for the Treatment of Newly Diagnosed Glioblastoma

Phase 1 Terminated

Glioblastoma, Gliosarcoma

NCT04421378 2024-12-16

A Study of Selinexor in Combination With Standard of Care Therapy for Newly Diagnosed or Recurrent Glioblastoma

Phase 1/2 Terminated

74 enrolled 23 charts

Glioblastoma

NCT03363659 2024-10-03

Disulfiram and Copper Gluconate With Temozolomide in Unmethylated Glioblastoma Multiforme

Phase 2 Terminated

15 enrolled 9 charts

Glioblastoma

NCT00555399 2024-08-22

Vorinostat, Isotretinoin and Temozolomide in Adults With Recurrent Glioblastoma Multiforme (GBM)

Phase 1/2 Terminated

55 enrolled 19 charts

Glioblastoma

NCT04324840 2024-07-26

A Study of CC-90010 in Combination With Temozolomide With or Without Radiation Therapy in Participants With Newly Diagnosed Glioblastoma

Phase 1 Terminated

Metatropic dwarfism, Glioblastoma

NCT02085304 2024-04-19

Tumor Resection and Gliadel® Wafers, Followed by Temodar® With Standard Radiation or GammaKnife® for New GBM

Phase 1/2 Terminated

Glioblastoma

NCT02880410 2024-04-12

FLAG

Phase 1 Terminated

Glioblastoma

NCT03927222 2024-04-08

I-ATTAC

Phase 2 Terminated

6 enrolled 7 charts

Glioblastoma, Tetanus

NCT03705351 2024-03-04

Tumor Treating Fields With Chemoradiation in Newly Diagnosed GBM

Phase 1 Terminated

7 enrolled 12 charts

Brain Neoplasms, Glioblastoma

NCT02168270 2023-11-24

Temozolomide and Ascorbic Acid in Treating Patients With Recurrent High-Grade Glioma

Phase 1 Terminated

4 enrolled 6 charts

Astrocytoma, Glioblastoma, Oligodendroglioma, Gliosarcoma

NCT02530502 2023-11-18

Radiation Therapy With Temozolomide and Pembrolizumab in Treating Patients With Newly Diagnosed Glioblastoma

Phase 1 Terminated

Glioblastoma

NCT01700569 2023-02-21

FOLAGLI

Phase 1 Terminated

Glioblastoma, Glioma

NCT03119064 2022-12-13

329

Phase 1/2 Terminated

12 enrolled 13 charts

Glioblastoma

NCT02864368 2022-06-09

PERFORMANCE

Phase 1 Terminated

27 enrolled 13 charts

Glioblastoma

NCT00669669 2022-05-18

O6-Benzylguanine-Mediated Tumor Sensitization With Chemoprotected Autologous Stem Cell in Treating Patients With Malignant Gliomas

Phase 1/2 Terminated

12 enrolled 13 charts

Glioblastoma, Gliosarcoma

NCT01587144 2021-10-19

Safety and Efficacy Study of Lucanthone When Used in Combination With Temozolomide(TMZ) and Radiation to Treat Glioblastoma Multiforme(GBM)

Phase 2 Terminated

Glioblastoma

NCT01110876 2021-08-25

Phase I / II Vorinostat, Erlotinib and Temozolomide for Recurrent Glioblastoma Multiforme (GBM)

Phase 1/2 Terminated

21 enrolled 8 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT02046187 2021-06-16

Ketogenic Diet With Radiation and Chemotherapy for Newly Diagnosed Glioblastoma

Phase 1/2 Terminated

Brain Neoplasms, Glioblastoma, Glioma

NCT03419403 2021-04-14

UNITE Study: Understanding New Interventions With GBM ThErapy

Phase 3 Terminated

40 enrolled 16 charts

Glioblastoma, Neoplasms

NCT02340156 2021-03-03

Phase II Study of Combined Temozolomide and SGT-53 for Treatment of Recurrent Glioblastoma

Phase 2 Terminated

1 enrolled 8 charts

Glioblastoma

NCT00756106 2020-05-13

MRI Scans in Evaluating the Effects of Radiation Therapy and Chemotherapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Glioma

Phase NA Terminated

15 enrolled 6 charts

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT01478321 2020-03-12

Efficacy of Hypofractionated XRT w/Bev. + Temozolomide for Recurrent Gliomas

Phase 2 Terminated

54 enrolled 10 charts

Astrocytoma, Ependymoma, Glioblastoma, Oligodendroglioma

NCT02414165 2020-02-07

Toca5

Phase 2/3 Terminated

Astrocytoma, Glioblastoma, Recurrence

NCT03246113 2019-08-13

Tolerability of Cannabis in Patients Receiving Concurrent Chemoradiation for Glioblastoma

Phase 1 Terminated

Glioblastoma

NCT00915694 2019-04-23

Nelfinavir Mesylate, Radiation Therapy, and Temozolomide in Treating Patients With Glioblastoma Multiforme

Phase 1 Terminated

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01186406 2019-02-15

Gliadel, XRT, Temodar, Avastin Followed by Avastin, Temodar for Newly Diagnosed Glioblastoma Multiforme (GBM)

Phase 2 Terminated

41 enrolled 9 charts

Glioblastoma, Glioma, Gliosarcoma

NCT01044966 2019-02-12

A Study of Intraventricular Liposomal Encapsulated Ara-C (DepoCyt) in Patients With Recurrent Glioblastoma

Phase 1/2 Terminated

12 enrolled 12 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT00734526 2018-11-09

Phase I Portion of Phase I/II Sorafenib With Radiation and Temozolomide in Newly Diagnosed Glioblastoma or Gliosarcoma

Phase 1 Terminated

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT00895960 2018-11-08

Dasatinib Plus Radiation Therapy/Temozolomide in Newly-Diagnosed Glioblastoma

Phase 1 Terminated

Brain Diseases, Central Nervous System Diseases, Glioblastoma, Gliosarcoma

NCT02850744 2018-10-19

Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamic Effects of PQR309 in Glioblastoma Patients

Phase 2 Terminated

Glioblastoma

NCT01868906 2018-08-24

FMISOPETSCS

Phase 2 Terminated

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT00471653 2018-07-09

Pharmacokinetics in Patients With Newly Diagnosed High-Grade Glioma Receiving Temozolomide and Radiation Therapy

CNSClassical hematologySarcoma

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Thrombocytopenia, Central Nervous System Neoplasms, Gliosarcoma

NCT00238277 2018-06-27

Temozolomide During and After Radiation Therapy in Treating Patients Who Have Undergone Previous Surgery and Placement of Gliadel Wafers for Newly Diagnosed Glioblastoma Multiforme

Phase 2 Terminated

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT02254954 2018-02-27

Clinical Study on Macitentan, RT and TMZ Concurrent Therapy Followed by Maintenance Macitentan and TMZ in Newly Diagnosed Glioblastoma

Phase 1 Terminated

Glioblastoma

NCT02510950 2017-11-17

Neoepitope-based Personalized Vaccine Approach in Patients With Newly Diagnosed Glioblastoma

Phase 1 Terminated

Glioblastoma

NCT02329795 2017-10-12

IDEPREG

Glioblastoma

NCT02039778 2017-06-05

STRONG

Phase NA Terminated

4 enrolled 8 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT00436436 2017-03-28

O(6)-Benzylguanine and Temozolomide in Treating Patients With Glioblastoma Multiforme That Did Not Respond to Previous Temozolomide and Radiation Therapy

Phase 2 Terminated

12 enrolled 10 charts

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT02394665 2017-01-05

Dose Escalated MRSI Guided Radiation Therapy in Glioblastoma

Phase 2 Terminated

1 enrolled 3 charts

Glioblastoma, Gliosarcoma

NCT01517776 2015-07-21

HGG-CilMetro

Phase 2 Terminated

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Glioma, Recurrence

NCT00761280 2014-11-14

SAPPHIRE

Phase 3 Terminated

27 enrolled 28 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms

NCT00508456 2012-01-16

Dietary Methionine Restriction Plus Temozolomide for Recurrent GBM

Phase 1 Terminated

Glioblastoma

NCT00516282 2011-08-26

VNP40101M and Temozolomide in Treating Patients With Progressive or Relapsed Malignant Glioma

Phase 1 Terminated

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00615186 2011-02-10

Glass-Art

Phase 3 Terminated

Glioblastoma

NCT00003567 2010-06-11

Gene Therapy and Chemotherapy in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma

Phase 1 Terminated

CNSLymphoidOther hematologic neoplasmSarcoma

Astrocytoma, Brain Neoplasms, Burkitt Lymphoma, Ependymoma, Glioblastoma, Glioma, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Oligodendroglioma, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00376103 2009-09-18

Radiation Boost for Newly Diagnosed Glioblastoma Multiforme

Phase 1/2 Terminated

Brain Neoplasms, Glioblastoma