Clinical Trials

30 enrolled

Glioblastoma, Glioma

NCT03478462 2026-03-18

CLOVER-2

CNSGenitourinaryLymphoidSarcoma

30 enrolled

Diffuse Intrinsic Pontine Glioma, Ependymoma, Glioblastoma, Glioma, Hodgkin Disease, Lymphoma, Lymphoma, Non-Hodgkin, Medulloblastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT04678648 2026-03-18

A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

CNSGastrointestinalThoracic

134 enrolled

Colonic Neoplasms, Glioblastoma, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Disease Progression

NCT07480941 2026-03-18

DUAL-CAR-NK-GB

36 enrolled

Glioblastoma, Glioma

NCT05109728 2026-03-16

A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Standard of Care and in Recurrent Glioblastoma as a Single Agent.

65 enrolled

Glioblastoma

NCT07455045 2026-03-06

A Phase I Study of FZ-AD005 in Patients With High-Grade Glioma (HGG)

Glioblastoma, Glioma

NCT05938387 2026-02-18

Safety and Tolerability of CVGBM in Adults With Newly Diagnosed MGMT-Unmethylated Glioblastoma or Astrocytoma

37 enrolled

Glioblastoma

NCT05739942 2026-02-03

Dose Finding Study of [177Lu]Lu-NeoB in Newly Diagnosed Glioblastoma and in Recurrent Glioblastoma

Glioblastoma

NCT05627323 2026-01-29

CAR T Cells in Patients With MMP2+ Recurrent or Progressive Glioblastoma

42 enrolled

Glioblastoma

NCT05450744 2026-01-21

IPAX-2

12 enrolled

Glioblastoma, Neoplasms

NCT05977322 2025-12-24

A Phase I Study of [177Lu]Lu-FF58 in Patients With Advanced Solid Tumors.

24 enrolled

CNSGastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Glioblastoma, Pancreatic Neoplasms, Stomach Neoplasms

NCT03423628 2025-12-22

A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer

180 enrolled

Brain Neoplasms, Glioblastoma, Inhibition, Psychological, Meningeal Neoplasms, Hereditary Sensory and Autonomic Neuropathies

NCT04541082 2025-12-18

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

102 enrolled

CNSSarcoma

Typical Teratoid Rhabdoid Tumor, Astrocytoma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Oligodendroglioma, Pinealoma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma

NCT07244835 2025-12-08

A Study of DEG6498 in Participants With Solid Tumors

CNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

100 enrolled

Glioblastoma, Carcinoma, Hepatocellular, Kidney Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Neurofibrosarcoma

NCT04982926 2025-10-14

A Study of TAS2940 in Participants With Locally Advanced or Metastatic Solid Tumor Cancer

29 enrolled

BreastCNSThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Glioblastoma

NCT01107522 2025-09-09

Safety and Tolerability of Carboxyamidotriazole Orotate (CTO) in Solid Tumors or With Temodar® in Glioblastoma or Other Recurrent Malignant Gliomas or in Combination With Temodar® and Radiation Therapy for Patients With Newly Diagnosed Glioblastoma and Malignant Gliomas

Phase 1 Unknown

100 enrolled

Glioblastoma, Glioma

NCT03679754 2025-08-28

Evaluation of Ad-RTS-hIL-12 + Veledimex in Subjects With Recurrent or Progressive Glioblastoma, a Substudy to ATI001-102

36 enrolled 21 charts

Glioblastoma

NCT05376800 2025-08-24

A Study to Determine How BI 907828 (Brigimadlin) is Taken up in the Tumor (Phase 0) and to Determine the Highest Dose of BI 907828 (Brigimadlin) That Could be Tolerated (Phase 1a) in Combination With Radiation Therapy in People With a Brain Tumor Called Glioblastoma

24 enrolled

Glioblastoma

NCT05222802 2025-08-17

A Study to Evaluate ERAS-801 in Patients With Recurrent Glioblastoma (THUNDERBBOLT-1)

52 enrolled

Glioblastoma

NCT03636477 2025-08-12

A Study of Ad-RTS-hIL-12 With Veledimex in Combination With Nivolumab in Subjects With Glioblastoma; a Substudy to ATI001-102

21 enrolled 36 charts

Glioblastoma

NCT02974738 2025-07-10

MK-6482-001

120 enrolled

CNSGenitourinary

Carcinoma, Renal Cell, Glioblastoma, Kidney Neoplasms, Neoplasm Metastasis

NCT06773481 2025-07-09

BC008-1A Injection for Recurrent CNS WHO G4 Glioma

Glioblastoma, Glioma

NCT05879367 2025-06-25

Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma

66 enrolled

Astrocytoma, Glioblastoma

NCT05362409 2025-06-19

Study to Evaluate 5-ALA Combined With CV01 Delivery of Ultrasound in Recurrent High Grade Glioma

22 enrolled

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms

NCT05226494 2025-06-04

Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma

34 enrolled

Glioblastoma, Glioma

NCT02766699 2025-06-03

CerebralEDV

9 enrolled

Brain Neoplasms, Glioblastoma, Neoplasms, Neoplasms by Site, Recurrence, Disease Progression

NCT06902350 2025-05-25

Safety, Pharmacokinetics and Preliminary Efficacy of CS231295 in Advanced Solid Tumors

102 enrolled

CNSThoracic

Glioblastoma, Neoplasms, Small Cell Lung Carcinoma

NCT05187624 2025-05-22

A Study Evaluating the Safety, Pharmacokinetic and Anti-tumor Activity of RO7428731 in Participants With Glioblastoma

36 enrolled

Glioblastoma

NCT02026271 2025-04-16

A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Glioblastoma or Malignant Glioma

40 enrolled 22 charts

Glioblastoma

NCT05495295 2025-04-08

PhAST

149 enrolled

Glioblastoma, Neoplasm Metastasis, Neoplasms

NCT05460507 2025-03-30

Safety & Efficacy/Tolerability of Rhenium-186 NanoLiposomes (186RNL) for Patients Who Received a Prior 186RNL Treatment

Brain Neoplasms, Glioblastoma, Glioma

NCT05769660 2025-03-10

A Study to Evaluate Safety and Efficacy of BEY1107 in Combination with Temozolomide in Patients with Recurrent or Progressive Glioblastoma Multiforme (GBM)

12 enrolled

Glioblastoma

NCT03576612 2025-02-14

GMCI

41 enrolled

Glioblastoma, Glioma

NCT05324501 2025-02-10

MAGIC-G1

4 enrolled

Glioblastoma

NCT06469138 2025-01-29

8479217

CNSDermatologicGastrointestinalMyeloidOther hematologic neoplasmOther solid neoplasmThoracic

6 enrolled 17 charts

Mesothelioma, Malignant, COVID-19, Carcinoma, Non-Small-Cell Lung, Glioblastoma, Melanoma, Myelodysplastic Syndromes, Pancreatic Neoplasms, Leukemia, Myeloid, Acute

NCT04404569 2024-12-20

ETERNITI

5 enrolled

Glioblastoma, Glioma, Neoplasms

NCT04908176 2024-12-13

A Drug-drug Interaction Study of Avapritinib and Midazolam

CNSGastrointestinalSarcoma

10 enrolled

Glioblastoma, Neoplasms, Recurrence, Gastrointestinal Stromal Tumors

NCT05698199 2024-12-06

Study to Evaluate the Safety, Tolerability, Immunogenicity and Preliminary Efficacy of ITI-1001 In Patients With Newly Diagnosed Glioblastoma (GBM)

10 enrolled

Glioblastoma

NCT05831995 2024-12-06

Safety and Effectiveness of ABM-168 in Adults with Advanced Solid Tumors.

CNSDermatologicGastrointestinalThoracic

12 enrolled

Brain Neoplasms, Glioblastoma, Lung Neoplasms, Melanoma, Pancreatic Neoplasms, Colorectal Neoplasms

NCT05561374 2024-11-29

Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients with Recurrent High-Grade Glioma

16 enrolled

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT03296696 2024-10-29

Study of AMG 596 in Patients With EGFRvIII Positive Glioblastoma

30 enrolled 29 charts

Phase 1 Enrolling by invitation

Glioblastoma, Glioma

NCT06616727 2024-09-27

The Safety and Efficacy of SNC-109 CAR-T Cells Therapy the rGBM

50 enrolled

Glioblastoma

NCT04933422 2024-08-21

CM93 Treatment in Subjects With Epidermal Growth Factor Receptor (EGFR)-Modified Recurrent Glioblastoma (rGBM)

72 enrolled

Glioblastoma

NCT06524063 2024-07-29

Targeted Survivin DC Cell Injection for the Treatment of GBM

9 enrolled