Clinical Trials Browser

Phase 3 × OTHER × Glioblastoma × Clear all

NCT05095376 2026-05-19

Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma

Phase 3 Active not recruiting

Glioblastoma, Gliosarcoma

NCT07452458 2026-05-04

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

Phase 3 Not yet recruiting

Glioblastoma

NCT01507506 2026-04-14

SPECTRO GLIO

Phase 3 Terminated

Glioblastoma

NCT06388733 2026-04-01

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

Phase 3 Recruiting

Brain Neoplasms, Glioblastoma

NCT03663725 2026-03-30

StrateGlio

Phase 3 Active not recruiting

Glioblastoma

NCT07461948 2026-03-10

Advanced Imaging Techniques for Evaluating the Tumor Immune Microenvironment in Glioblastoma Patients

Phase 3 Recruiting

Glioblastoma

NCT06448286 2026-02-19

PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastoma

Phase 3 Not yet recruiting

Glioblastoma

NCT07376304 2026-01-29

BrainUS-AI

Phase 3 Not yet recruiting

Brain Neoplasms, Glioblastoma, Glioma

NCT05326464 2025-12-15

Tofacitinib in Recurrent GBM Patients

Phase 3 Active not recruiting

Glioblastoma

NCT02685605 2025-10-14

INTRAGO-II

Phase 3 Active not recruiting

Glioblastoma

NCT01811121 2025-09-15

RESECT

Phase 3 Completed

Glioblastoma

NCT05439278 2025-05-21

Conventional Versus Hypofractionated Radiotherapy With Temozolomide in Elderly Glioblastoma

Phase 3 Recruiting

Glioblastoma

NCT06749925 2025-04-01

Clinical Trial Assessing the Efficacy and Safety of Dendritic Cell-Based Immunotherapy for Glioblastoma

Phase 3 Not yet recruiting

Glioblastoma

NCT05271240 2024-09-19

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

Phase 3 Recruiting

Brain Neoplasms, Glioblastoma, Glioma

NCT06477939 2024-06-27

THREE-GLEES

Phase 3 Not yet recruiting

Hypoxia, Brain Neoplasms, Glioblastoma

NCT05718466 2023-07-17

Stereotactic Radiology Versus Chemotherapy for Recurrent/Progressive Glioblastoma After Second-Line Chemotherapy

Phase 3 Completed

35 enrolled 13 charts

Glioblastoma, Recurrence

NCT02761070 2023-03-08

RE-GEND

Phase 3 Unknown

Glioblastoma, Recurrence, Disease Progression

NCT03291977 2022-11-09

FLEGME

Phase 3 Completed

Glioblastoma

NCT05600491 2022-10-31

A Phase III Study of Postoperative Early Temozolomide Treatment Plus STUPP Regimen for Newly Diagnosed GBM Multiforme

Phase 3 Unknown

Glioblastoma

NCT03243461 2022-06-06

HIT-HGG-2013

Phase 3 Unknown

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neuroepithelial

NCT00369785 2021-10-20

Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors

Phase 3 Completed

198 enrolled 10 charts

Astrocytoma, Brain Neoplasms, Craniopharyngioma, Ependymoma, Fatigue, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neoplasm Metastasis, Oligodendroglioma, Pinealoma, Radiation Injuries, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

NCT00031798 2021-09-09

Methylphenidate to Improve Quality of Life in Patients Undergoing Radiation Therapy for Brain Tumors

Phase 3 Terminated

Astrocytoma, Brain Neoplasms, Depression, Ependymoma, Fatigue, Glioblastoma, Glioma, Meningioma, Oligodendroglioma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

NCT04829097 2021-04-02

Neoadjuvant Temozolomide Combined With Simultaneous IMRT for Treatment of Glioblastoma

Phase 3 Unknown

Glioblastoma

NCT04536649 2020-09-02

Proton and Heavy Ion Beam Radiation vs. Photon Beam Radiation for Newly Diagnosed Glioblastoma.

Phase 3 Unknown

Glioblastoma

NCT01805453 2020-05-08

ASTER

Phase 3 Completed

Edema, Glioblastoma

NCT03633552 2018-08-16

Efficacy of Two Temozolomide Regimens in Adjuvant Treatment of Patients With Brain High Grade Glioma

Phase 3 Unknown

Astrocytoma, Glioblastoma

NCT01765088 2018-02-23

A Phase III Trial on Adjuvant Temozolomide With or Without Interferon-alpha in Newly Diagnosed High-grade Gliomas

Phase 3 Unknown

Astrocytoma, Glioblastoma, Glioma

NCT02629757 2018-02-23

β-elemene

Phase 3 Unknown

Astrocytoma, Glioblastoma, Glioma

NCT01149109 2017-06-14

CeTeG

Phase 3 Completed

Glioblastoma

NCT01830101 2016-03-16

A Phase III Study of Re-Irradiation in Recurrent Glioblastoma

Phase 3 Withdrawn

Glioblastoma

NCT01364064 2016-02-25

Conventional Adjuvant Temozolomide With Dose Intensive Temozolomide in Patients With Newly Diagnosed Glioblastoma

Phase 3 Completed

Glioblastoma

NCT01132547 2015-07-02

Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer

Phase 3 Terminated

22 enrolled 9 charts

CNSGastrointestinalGenitourinaryGynecologicLymphoidSarcoma

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Body Weight Changes, Bone Neoplasms, Cachexia, Chondrosarcoma, Fibrosarcoma, Glioblastoma, Hemangiosarcoma, Liposarcoma, Medulloblastoma, Nausea, Neoplasms, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Sarcoma, Sarcoma, Ewing, Mast-Cell Sarcoma, Osteosarcoma, Testicular Neoplasms, Vomiting, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Hepatoblastoma, Sarcoma, Endometrial Stromal, Neuroectodermal Tumors, Primitive, Peripheral, Neoplasms, Neuroepithelial, Optic Nerve Glioma

NCT00003564 2012-02-22

Procarbazine and Isotretinoin in Treating Patients With Recurrent Primary Malignant Gliomas

Phase 3 Withdrawn

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT01502241 2011-12-30

Methusalem

Phase 3 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma

NCT00118222 2010-06-11

High Light and Low Light Dose PDT in Glioma

Phase 3 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00224978 2009-11-18

Chloroquine for Treatment of Glioblastoma Multiforme

Phase 3 Completed

Glioblastoma

NCT00430911 2007-02-02

Radiotherapy for Malignant Astrocytomas in the Elderly

Phase 3 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma