NCT07416188 2026-04-16
Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma
National Institutes of Health Clinical Center (CC)
Phase 1/2 Not yet recruiting
Clinical Trials
67 trialsNCT07422363 2026-04-13
Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent Glioblastoma
National Cancer Institute (NCI)
Phase 1 Not yet recruiting
NCT07468136 2026-04-13
Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas
Mayo Clinic
Phase 1/2 Not yet recruiting
NCT07521657 2026-04-13
NF118
University of Alabama at Birmingham
Phase 2 Not yet recruiting
NCT07512154 2026-04-07
Precision Radiotherapy Enabled by Molecular MRI
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase NA Not yet recruiting
NCT07515924 2026-04-07
Oral Gallium Maltolate for Recurrent Glioblastoma
Medical College of Wisconsin
Phase EARLY_PHASE1 Not yet recruiting
NCT07431216 2026-03-30
A Phase 1b/2a Study to Evaluate the Safety, Pharmacokinetics, and Objective Response of STAR-001 (LP-184) in Combination With Spironolactone in Supratentorial Glioblastoma at First Progression
Starlight Therapeutics Inc.
Phase 1/2 Not yet recruiting
NCT07375992 2026-03-27
MELODY
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase NA Not yet recruiting
NCT07492836 2026-03-25
HipoGBM
Hospital do Coracao
Phase NA Not yet recruiting
NCT07493447 2026-03-25
Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical Procedures
Vanderbilt-Ingram Cancer Center
Phase EARLY_PHASE1 Not yet recruiting
NCT07089758 2026-03-23
A Study for Cerebral Open Flow Microperfusion
Mayo Clinic
Phase NA Not yet recruiting
NCT07392957 2026-03-23
Safety and Efficacy of CTX-009 With or Without CTX-471 for Recurrent Glioblastoma
Washington University School of Medicine
Phase 1/2 Not yet recruiting
NCT07464925 2026-03-20
A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma
Tetragon Biosciences Ltd
Phase 1 Not yet recruiting
NCT07485049 2026-03-20
Phase 0/2 PD-Trigger Study of BGB-58067 in Newly Diagnosed Glioblastoma Patients With MTAP-Deleted Tumors
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Not yet recruiting
NCT07472387 2026-03-16
Andro-iGlio
Assistance Publique - Hôpitaux de Paris
Phase NA Not yet recruiting
NCT07462507 2026-03-10
Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1
Washington University School of Medicine
Phase 2 Not yet recruiting
NCT07455045 2026-03-06
A Phase I Study of FZ-AD005 in Patients With High-Grade Glioma (HGG)
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.
Phase 1 Not yet recruiting
NCT07452458 2026-03-05
Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma
NRG Oncology
Phase 3 Not yet recruiting
NCT07346144 2026-03-04
ADePT
Trogenix ltd
Phase 1/2 Not yet recruiting
NCT07439172 2026-02-27
PRC
The Cooper Health System
Phase 2 Not yet recruiting
NCT07422896 2026-02-20
Bvax
Northwestern University
Phase 1 Not yet recruiting
NCT06448286 2026-02-19
PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastoma
Jonsson Comprehensive Cancer Center
Phase 3 Not yet recruiting
NCT07218367 2026-02-13
Phase I Trial of pH Resections of GBM at VA
VA Office of Research and Development
Phase 1 Not yet recruiting
NCT07387666 2026-02-06
Imaging Acetadote Metabolism in Glioblastoma
University of Texas Southwestern Medical Center
Phase EARLY_PHASE1 Not yet recruiting
NCT07389278 2026-02-05
Combination ADI-PEG 20, TMZ, and RT for Treatment of Newly Diagnosed High-grade Glioma (HGG)
University of California, San Francisco
Phase 1/2 Not yet recruiting
NCT07385846 2026-02-04
Pilot Study of Navigated Focused Ultrasound and Pembrolizumab in the Treatment of Recurrent WHO Grade 4 IDH-Wildtype Glioblastoma With Mismatch Repair Deficiency
University of Cincinnati
Phase 1 Not yet recruiting
NCT07368283 2026-01-30
Limited Target Volume Radiotherapy After Glioblastoma Surgery
Jiangxi Provincial Cancer Hospital
Phase NA Not yet recruiting
NCT07376304 2026-01-29
BrainUS-AI
Hospital del Rio Hortega
Phase 3 Not yet recruiting
NCT07356973 2026-01-26
OPTICAL
CRISM Therapeutics LTD
Phase 2 Not yet recruiting
NCT07365280 2026-01-26
Neoantigen-Pulsed Autologous Dendritic Cell Vaccine Combined With Temozolomide for Newly Diagnosed Glioblastoma
ZSky Biotech Inc
Phase 2 Not yet recruiting
NCT07349693 2026-01-20
Cerebraca-02/3
Everfront Biotech Co., Ltd.
Phase 2/3 Not yet recruiting
NCT07284628 2025-12-16
ReVoGlio
University of Zurich
Phase 2 Not yet recruiting
NCT07274397 2025-12-10
EARLYBRAINPET
Beta Emitting Accurate Monitored Systems
Phase NA Not yet recruiting
NCT07244666 2025-11-24
Safety and Preliminary Efficacy of a Metabolically Armed Chimeric Antigen Receptor T Cell Therapy Targeting EGFRvIII for Recurrent Glioblastoma
Second Affiliated Hospital, School of Medicine, Zhejiang University
Phase EARLY_PHASE1 Not yet recruiting
NCT07211841 2025-11-19
GLIOMIT
Centre Hospitalier Universitaire, Amiens
Phase NA Not yet recruiting
NCT04903795 2025-11-03
BRiTE
Duke University
Phase 1 Not yet recruiting
NCT04373785 2025-10-21
NG101m Adjuvant Therapy in Glioblastoma Patients
NeuGATE Theranostics
Phase 1/2 Not yet recruiting
NCT06804655 2025-10-02
EViDENCE-BT
University of Zurich
Phase 2 Not yet recruiting
NCT06492486 2025-09-16
GLADIATOR
Tata Memorial Centre
Phase 2 Not yet recruiting
NCT07138001 2025-08-22
Phase 2 Clinical Trial of KH617
Chengdu Kanghong Pharmaceutical Group Co., Ltd.
Phase 2 Not yet recruiting
NCT06455189 2025-08-13
Magnetic Resonance Fingerprinting Guided Extended Resection in Glioblastomas
Case Comprehensive Cancer Center
Phase 1 Not yet recruiting
NCT06617208 2025-08-08
PIONEER
Erasmus Medical Center
Phase NA Not yet recruiting
NCT07047066 2025-07-02
A Phase II Clinical Study to Evaluate the Efficacy and Safety of Flazoparib Combined With Temozolomide After the Completion of Standard Concurrent Chemoradiotherapy (CCRT) in Newly Diagnosed Glioblastoma
Tongji Hospital
Phase 2 Not yet recruiting
NCT07029100 2025-06-19
ORGA-GLIO
Centre Henri Becquerel
Phase NA Not yet recruiting
NCT01777919 2025-05-25
GLIODIS
Olympion Medical Center
Phase 2 Not yet recruiting
NCT06869577 2025-04-29
SUGRI
Rigshospitalet, Denmark
Phase NA Not yet recruiting
NCT06929819 2025-04-16
Research on the Safety and Efficacy of Intraoperative Radiation Therapy in Malignant Cerebral Tumor
First Affiliated Hospital, Sun Yat-Sen University
Phase NA Not yet recruiting
NCT06894225 2025-04-06
Proof-of-Concept Study of ACT001 in Adult Patients With Recurrent Glioblastoma Harbouring STAT3-High Signature
National Neuroscience Institute
Phase 2 Not yet recruiting
NCT06749925 2025-04-01
Clinical Trial Assessing the Efficacy and Safety of Dendritic Cell-Based Immunotherapy for Glioblastoma
University of Sao Paulo General Hospital
Phase 3 Not yet recruiting
NCT06781372 2025-03-13
GlioPDO
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Phase NA Not yet recruiting