Clinical Trials Browser

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NCT05275478 2026-04-15

Safety and Tolerability of TNG908 in Patients With MTAP-deleted Solid Tumors

Phase 1/2 Terminated

CNSGastrointestinalOther solid neoplasmSarcomaThoracic

Glioblastoma, Mesothelioma, Sarcoma, Cholangiocarcinoma, Neurofibrosarcoma

NCT01507506 2026-04-14

SPECTRO GLIO

Phase 3 Terminated

Glioblastoma

NCT01743950 2026-03-25

A Phase II Study of Pulse Reduced Dose Rate Radiation Therapy With Bevacizumab

Phase 2 Terminated

49 enrolled 19 charts

Glioblastoma, Glioma

NCT05753007 2026-03-16

A Clinical Trial of a Hemp-Derived, High Cannabidiol Product for Anxiety in Glioblastoma Patients

Phase 2 Terminated

2 enrolled 13 charts

Glioblastoma

NCT01068782 2026-02-25

Multiple Doses and Regimens of Cabozantinib in Subjects With Grade IV Astrocytic Tumors in First or Second Relapse

Phase 2 Terminated

19 enrolled 10 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT02942264 2026-02-23

Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma

Phase 1/2 Terminated

53 enrolled 22 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Recurrence, Gliosarcoma

NCT04825275 2026-01-23

Neuro-pharmacological Properties of Repurposed Posaconazole in Glioblastoma: A Phase 0 Clinical Trial

Phase EARLY_PHASE1 Terminated

7 enrolled 12 charts

Brain Neoplasms, Glioblastoma

NCT04869449 2026-01-07

Neuro-pharmacological Properties of Repurposed Ketoconazole in Glioblastomas

Phase EARLY_PHASE1 Terminated

Brain Neoplasms, Glioblastoma

NCT05267106 2025-12-30

FIGHT-209

Phase 2 Terminated

83 enrolled 18 charts

Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT05977322 2025-12-24

A Phase I Study of [177Lu]Lu-FF58 in Patients With Advanced Solid Tumors.

Phase 1 Terminated

CNSGastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Glioblastoma, Pancreatic Neoplasms, Stomach Neoplasms

NCT06359379 2025-12-18

Ropidoxuridine as a Radiosensitizer in Newly Diagnosed IDH-Wildtype Glioblastoma With Unmethylated MGMT Promoter

Phase 2 Terminated

Glioblastoma

NCT03107780 2025-11-13

Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancer

Phase 1 Terminated

Glioblastoma, Gliosarcoma

NCT04209790 2025-11-10

NeoGlio

Phase 2 Terminated

2 enrolled 7 charts

Glioblastoma, Glioma

NCT04424966 2025-10-24

Infigratinib in Recurrent High-Grade Glioma Patients

Phase EARLY_PHASE1 Terminated

7 enrolled 18 charts

Glioblastoma, Glioma

NCT02711137 2025-10-21

Open-Label Safety and Tolerability Study of INCB057643 in Subjects With Advanced Malignancies

Phase 1/2 Terminated

137 enrolled 31 charts

BreastCNSGastrointestinalGenitourinaryGynecologicLymphoidMyeloidOther hematologic neoplasmPlasma cellThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Glioblastoma, Leukemia, Lymphoma, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Lymphoma, Large B-Cell, Diffuse, Primary Myelofibrosis

NCT03868943 2025-10-21

JAZZ

Phase 2 Terminated

2 enrolled 5 charts

Glioblastoma, Glioma

NCT04982926 2025-10-14

A Study of TAS2940 in Participants With Locally Advanced or Metastatic Solid Tumor Cancer

Phase 1 Terminated

BreastCNSThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Glioblastoma

NCT04712721 2025-10-10

Study of [68Ga]-FF58 in Patients With Selected Solid Tumors Expected to Overexpress αvβ3 and αvβ5 Integrins.

Phase EARLY_PHASE1 Terminated

Brain Neoplasms, Breast Neoplasms, Glioblastoma

NCT03347617 2025-09-09

Ferumoxytol MRI in Assessing Response to Pembrolizumab in Patients With Glioblastoma

Phase 2 Terminated

52 enrolled 15 charts

Glioblastoma

NCT03149575 2025-09-04

STAR-3

Phase 3 Terminated

Brain Neoplasms, Glioblastoma, Glioma

NCT04074785 2025-08-17

SCCC-06319

Phase EARLY_PHASE1 Terminated

Brain Neoplasms, Glioblastoma

NCT03330197 2025-08-12

A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG

Phase 1/2 Terminated

6 enrolled 14 charts

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Glioma

NCT03018288 2025-08-08

Radiation Therapy Plus Temozolomide and Pembrolizumab With and Without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)

Phase 2 Terminated

90 enrolled 24 charts

Glioblastoma, Glioma

NCT04963413 2025-08-06

RENEW: Feasibility of CMV RNA-Pulsed Dendritic Cells Vaccines for the Treatment of Newly Diagnosed Glioblastoma Patients.

Phase 1 Terminated

Glioblastoma

NCT05563272 2025-07-10

STARBURST

Phase 2 Terminated

CNSGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Nasopharyngeal Carcinoma, Mesothelioma, Malignant, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Glioblastoma, Carcinoma, Hepatocellular, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma, Small Cell Lung Carcinoma

NCT04406272 2025-06-10

VB-111 in Surgically Accessible Recurrent/Progressive GBM

Phase 2 Terminated

15 enrolled 14 charts

Glioblastoma

NCT05297864 2025-05-23

OU-SCC-PI-4G

Phase 2 Terminated

15 enrolled 13 charts

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT01430351 2025-05-07

Temozolomide, Memantine Hydrochloride, Mefloquine, and Metformin Hydrochloride in Treating Patients With Glioblastoma Multiforme After Radiation Therapy

Phase 1 Terminated

Glioblastoma, Gliosarcoma

NCT05388435 2025-05-04

Safety, Tolerability, PK/PD & Preliminary Efficacy of SKL27969 in Advanced Solid Tumors Patients

Phase 1/2 Terminated

BreastCNSThoracic

Carcinoma, Non-Small-Cell Lung, Glioblastoma, Triple Negative Breast Neoplasms

NCT04006119 2025-04-18

Study of Ad-RTS-hIL-12 + Veledimex in Combination With Cemiplimab in Subjects With Recurrent or Progressive Glioblastoma

Phase 2 Terminated

40 enrolled 14 charts

Glioblastoma

NCT04469699 2025-03-11

NOA11

Phase 2 Terminated

Glioblastoma

NCT05737212 2025-02-21

Studying the Safety, Efficacy, and Pharmacokinetic Characteristics of BNCT in Patients With Recurrent High-grade Gliomas

Phase 1/2 Terminated

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT02722512 2025-02-18

Trial of Heat Shock Protein Peptide Complex-96 (HSPPC-96) Vaccine

Phase 1 Terminated

Astrocytoma, Ependymoma, Glioblastoma

NCT05324501 2025-02-10

MAGIC-G1

Phase 1 Terminated

Glioblastoma

NCT01814813 2025-01-24

Vaccine Therapy With Bevacizumab Versus Bevacizumab Alone in Treating Patients With Recurrent Glioblastoma Multiforme That Can Be Removed by Surgery

Phase 2 Terminated

90 enrolled 13 charts

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT03717142 2025-01-15

Feasibility of the LUM Imaging System for Detection of Cancer to the Brain

Phase NA Terminated

Brain Neoplasms, Glioblastoma

NCT04397679 2025-01-15

Partial Brain RT, Temozolomide, Chloroquine, and TTF Therapy for the Treatment of Newly Diagnosed Glioblastoma

Phase 1 Terminated

Glioblastoma, Gliosarcoma

NCT02525692 2024-12-24

Oral ONC201 in Adult Recurrent Glioblastoma

Phase 2 Terminated

84 enrolled 14 charts 3 FDA

Glioblastoma

NCT04404569 2024-12-20

ETERNITI

Phase 1 Terminated

Glioblastoma, Glioma, Neoplasms

NCT04421378 2024-12-16

A Study of Selinexor in Combination With Standard of Care Therapy for Newly Diagnosed or Recurrent Glioblastoma

Phase 1/2 Terminated

74 enrolled 23 charts

Glioblastoma

NCT05831995 2024-12-06

Safety and Effectiveness of ABM-168 in Adults with Advanced Solid Tumors.

Phase 1 Terminated

CNSDermatologicGastrointestinalThoracic

Brain Neoplasms, Glioblastoma, Lung Neoplasms, Melanoma, Pancreatic Neoplasms, Colorectal Neoplasms

NCT02372409 2024-11-01

Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors

Phase 2 Terminated

6 enrolled 10 charts

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma, Optic Nerve Glioma

NCT03973918 2024-10-31

BRAF

Phase 2 Terminated

5 enrolled 15 charts

Astrocytoma, Glioblastoma, Glioma, Gliosarcoma

NCT03296696 2024-10-29

Study of AMG 596 in Patients With EGFRvIII Positive Glioblastoma

Phase 1 Terminated

30 enrolled 29 charts

Glioblastoma, Glioma

NCT04952571 2024-10-15

Combined Treatment of Camrelizumab and Bevacizumab for Adult Patients with Recurrent Glioblastoma (GBM)

Phase 2 Terminated

Glioblastoma

NCT03363659 2024-10-03

Disulfiram and Copper Gluconate With Temozolomide in Unmethylated Glioblastoma Multiforme

Phase 2 Terminated

15 enrolled 9 charts

Glioblastoma

NCT01246869 2024-10-01

Assessment of Primary and Metastatic Brain Tumor Hypoxia With Fluoromisonidazole, FDG and Water

Phase 1 Terminated

Brain Neoplasms, Glioblastoma, Glioma, Meningioma, Neoplasms

NCT00555399 2024-08-22

Vorinostat, Isotretinoin and Temozolomide in Adults With Recurrent Glioblastoma Multiforme (GBM)

Phase 1/2 Terminated

55 enrolled 19 charts

Glioblastoma

NCT03539731 2024-08-12

[18F]DASA-23 and PET Scan in Evaluating Pyruvate Kinase M2 Expression in Patients With Intracranial Tumors or Recurrent Glioblastoma and Healthy Volunteers

Phase 1 Terminated

Brain Neoplasms, Glioblastoma

NCT04324840 2024-07-26

A Study of CC-90010 in Combination With Temozolomide With or Without Radiation Therapy in Participants With Newly Diagnosed Glioblastoma

Phase 1 Terminated

Metatropic dwarfism, Glioblastoma