NCT03796273 2026-03-20
Ketoconazole Before Surgery in Treating Patients With Recurrent Glioma or Breast Cancer Brain Metastases
Wake Forest University Health Sciences
Phase EARLY_PHASE1 Terminated
Clinical Trials
32 trialsNCT04655404 2026-03-18
A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion
Nationwide Children's Hospital
Phase EARLY_PHASE1 Recruiting
NCT05577416 2026-03-18
AB-218-IIT-201
Melbourne Health
Phase EARLY_PHASE1 Completed
NCT06333899 2026-03-12
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion
Nationwide Children's Hospital
Phase EARLY_PHASE1 Recruiting
NCT05076513 2026-03-09
Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent Glioma
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Active not recruiting
NCT05182905 2026-03-09
AZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma Patients
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Active not recruiting
NCT04391595 2026-03-06
LY3214996 Plus Abemaciclib in Recurrent Glioblastoma Patients
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Completed
NCT05804227 2026-02-27
Window-of-Opportunity Trial of Ulixertinib for MAPK-Activated Gliomas
M.D. Anderson Cancer Center
Phase EARLY_PHASE1 Recruiting
NCT07210632 2026-02-27
Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG)
Vanderbilt-Ingram Cancer Center
Phase EARLY_PHASE1 Not yet recruiting
NCT06636162 2026-02-23
Window of Opportunity Study of DSP-0390 in Gliomas
Washington University School of Medicine
Phase EARLY_PHASE1 Recruiting
NCT05676489 2026-02-20
MeFAMP for Imaging System A Amino Acid Transport in Primary and Metastatic Brain Tumors
University of Alabama at Birmingham
Phase EARLY_PHASE1 Not yet recruiting
NCT05406700 2026-02-09
Niraparib In Recurrent IDH 1/2 Gliomas
Massachusetts General Hospital
Phase EARLY_PHASE1 Active not recruiting
NCT07050836 2026-02-04
Contrast Enhanced Ultrasound in Neurosurgery to Improve Glioma Visualization and Border Demarcation
University of Colorado, Denver
Phase EARLY_PHASE1 Recruiting
NCT07025226 2026-01-26
Senolytics
Mayo Clinic
Phase EARLY_PHASE1 Recruiting
NCT05851378 2026-01-12
Hyperpolarized Carbon-13 Alpha-ketoglutarate Imaging in IDH Mutant Glioma
University of California, San Francisco
Phase EARLY_PHASE1 Recruiting
NCT06829173 2026-01-02
Concurrent XRD-0394 With Radiation Therapy for High Grade Gliomas
NYU Langone Health
Phase EARLY_PHASE1 Recruiting
NCT04943913 2025-12-11
Study of GC101 TIL in Brain Glioma (Soochow2)
Shanghai Juncell Therapeutics
Phase EARLY_PHASE1 Recruiting
NCT05632562 2025-12-11
Multiparametic Metabolic and Hypoxic PET/MRI for Disease Assessment in High Grade Glioma
University of Alabama at Birmingham
Phase EARLY_PHASE1 Recruiting
NCT07077616 2025-12-08
TAMAVAQTM
Biogenea Pharmaceuticals Ltd.
Phase EARLY_PHASE1 Recruiting
NCT05553041 2025-12-04
18F-Fluciclovine PET-MRI in High-grade Glioma
Children's Hospital of Philadelphia
Phase EARLY_PHASE1 Recruiting
NCT05555550 2025-12-04
Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG
Children's Hospital of Philadelphia
Phase EARLY_PHASE1 Recruiting
NCT06209567 2025-12-03
A Study of 68Ga-PSMA-11 PET Scans in People With Brain Tumors
Memorial Sloan Kettering Cancer Center
Phase EARLY_PHASE1 Active not recruiting
NCT06072586 2025-11-20
A Phase 0/1 Study of BDTX-1535 in Recurrent High-Grade Glioma (rHGG) and Newly Diagnosed Glioblastoma (nGBM) Participants With EGFR Alterations or Fusions
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Recruiting
NCT05045027 2025-11-14
Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma
Jonsson Comprehensive Cancer Center
Phase EARLY_PHASE1 Active not recruiting
NCT05717153 2025-11-04
Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High Grade Glioma
Mayo Clinic
Phase EARLY_PHASE1 Recruiting
NCT04424966 2025-10-24
Infigratinib in Recurrent High-Grade Glioma Patients
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Terminated
NCT05634707 2025-09-22
Evaluation of Fluoxetine and Cytotoxic Lysosomal Stress in Glioma (FLIRT)
Duke University
Phase EARLY_PHASE1 Active not recruiting
NCT05023551 2025-09-16
Study of DSP-0390 in Patients With Recurrent High-Grade Glioma
Sumitomo Pharma America, Inc.
Phase EARLY_PHASE1 Active not recruiting
NCT01165632 2025-09-02
Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma
Mayo Clinic
Phase EARLY_PHASE1 Completed
NCT03893487 2025-07-11
PNOC016
University of California, San Francisco
Phase EARLY_PHASE1 Active not recruiting
NCT02970448 2025-06-19
Expedited Laser Interstitial Thermal Therapy + Chemoradiation For Newly Diagnosed High Grade Gliomas
Case Comprehensive Cancer Center
Phase EARLY_PHASE1 Completed
NCT03834740 2025-05-30
A Phase 0/I Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade Glioma Patients Scheduled for Resection
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Completed