Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Recruiting 90Active not recruiting 46Completed 27Not yet recruiting 18Terminated 7Enrolling by invitation 3Suspended 2Withdrawn 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2

Conditions

Leukemia, Myeloid, Acute 10Breast Neoplasms 9Neoplasms 8Carcinoma, Non-Small-Cell Lung 8Neoplasm Metastasis 7Lung Neoplasms 6Glioblastoma 6Precursor Cell Lymphoblastic Leukemia-Lymphoma 5Hematologic Neoplasms 5Colorectal Neoplasms 5Carcinoma, Hepatocellular 5Ovarian Neoplasms 4Myelodysplastic Syndromes 4Multiple Myeloma 4Carcinoma, Renal Cell 4Uterine Cervical Neoplasms 3Triple Negative Breast Neoplasms 3Sarcoma 3Prostatic Neoplasms 3Pancreatic Neoplasms 3Melanoma 3Head and Neck Neoplasms 3Urinary Bladder Neoplasms 2Solid Tumor 2Recurrence 2Rectal Neoplasms 2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Osteosarcoma 2Neoplasm, Residual 2NSCLC 2

Interventions

trametinib 1Everolimus 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Suspended × Glioma × 90 days × Clear all
NCT03952598 2026-05-22

Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy

National Institutes of Health Clinical Center (CC)

Phase 2 Suspended
42 enrolled
CNS

Glioma

NCT04485559 2026-04-13

Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)

University of California, San Francisco

Phase 1 Suspended
50 enrolled
CNS

Glioma

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