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Phase

Phase 1 2Phase 2 1Phase 1/2 1

Status

Withdrawn 1Unknown 1Completed 1Active not recruiting 1

Sponsor Class

INDUSTRY 4

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 4

Conditions

Glioma 4Glioblastoma 3Oligodendroglioma 2Astrocytoma 2Diffuse Intrinsic Pontine Glioma 1

Interventions

Temozolomide 159Bevacizumab 69Radiotherapy 68Magnetic Resonance Spectroscopy 68Irinotecan 31Surgical Procedures, Operative 27Radiation 24Carboplatin 23Specimen Handling 20Carmustine 20Blood Specimen Collection 20Nivolumab 19Aminolevulinic Acid 18Biopsy 17Lomustine 16pembrolizumab 13Radiotherapy, Intensity-Modulated 13Cyclophosphamide 13trametinib 12fluorodopa F 18 12X-Rays 12Radiosurgery 12Erlotinib Hydrochloride 12Topotecan 11Everolimus 11Magnetic Resonance Imaging 10IL13-PE38 10dabrafenib 9Etoposide 9Drug Therapy 9

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Glioma × OKN 007 × Clear all
NCT04388475 2025-08-12

Open-label Study Investigating of OKN-007 Combined With Temozolomide in Patients With Recurrent Glioblastoma

Oblato, Inc.

Phase 2 Completed
57 enrolled
CNS

Glioma

NCT05561374 2024-11-29

Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients with Recurrent High-Grade Glioma

Oblato, Inc.

Phase 1 Active not recruiting
16 enrolled
CNS

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT01672463 2023-03-29

OKN-007

Oblato, Inc.

Phase 1 Unknown
31 enrolled
CNS

Glioma

NCT03649464 2022-10-07

Investigation of Oral OKN-007 in Recurrent High-grade Glioma Participants

Oblato, Inc.

Phase 1/2 Withdrawn
CNS

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

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